Sakamoto Eiji

Research theme for competitive and other funds (11)：

2016 - 2019 Creation and application of a new hamster line lacking beta-B1 crystallin
2013 - 2016 Genetic analysis of molecular networks supporting cardiac T-tubules
2011 - 2012 Study on βB1-crystallin and Heart
2002 - 臨床検体を用いた病態パスウェイの解明
2000 - 2001 眼の色の視覚機能における動きの研究

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Papers (8)：

Ryuji Kato, Atsuo Nomura, Aiji Sakamoto, Yuki Yasuda, Koyuha Amatani, Sayuri Nagai, Yoko Sen, Yoshio Ijiri, Yoshikatsu Okada, Takehiro Yamaguchi, et al. Hydrogen gas attenuates embryonic gene expression and prevents left ventricular remodeling induced by intermittent hypoxia in cardiomyopathic hamsters. American journal of physiology. Heart and circulatory physiology. 2014. 307. 11. H1626-33-H1633
Misaki Muroya, Atsuo Nomura, Ryuji Kato, Yoshio Ijiri, Aiji Sakamoto, Takehiro Yamaguchi, Yasukatsu Izumi, Minoru Yoshiyama, Kazuhiko Tanaka, Tetsuya Hayashi. Intermittent Hypoxia Relevant to Sleep Apnea Increases Oxidative Stress and Accelerates Cardiac Remodeling in Cardiomyopathic Hamster. JOURNAL OF CARDIAC FAILURE. 2014. 20. 10. S204-S205
Aiji Sakamoto, Masaaki Kawashiri, Hatsue Ishibashi-Ueda, Yuka Sugamoto, Tsuyoshi Yoshimuta, Takeo Higashikata, Hitoshi Ogino, Hayato Tada, Tetsuo Konno, Kenshi Hayashi, et al. Expression and Function of Ephrin-B1 and Its Cognate Receptor EphB2 in Human Abdominal Aortic Aneurysm. International journal of vascular medicine. 2012. 2012. 127149-127149
Aiji Sakamoto, Yuka Sugamoto. Identification of a novel aldose reductase-like gene upregulated in the failing heart of cardiomyopathic hamster. Molecular and cellular biochemistry. 2011. 353. 1-2. 275-81
Liping Liu, Miriam Zacchia, Xuefei Tian, Laxiang Wan, Aiji Sakamoto, Masashi Yanagisawa, Robert J Alpern, Patricia A Preisig. Acid regulation of NaDC-1 requires a functional endothelin B receptor. Kidney international. 2010. 78. 9. 895-904

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MISC (44)：

Aiji Sakamoto, Yuka Sugamoto. A novel aldose reductase-like gene is overexpressed in cardiomyopathy of delta-sarcoglycan deficient hamster. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2010. 112. 244P-244P
Aiji Sakamoto, Hatsue Ueda, Yuka Sugamoto, Yuka Tokunaga, Tsuyoshi Yoshimuta, Takeo Higashikata, Hitoshi Ogino, Masakazu Yamagishi. Ephrin/Eph family genes in atherosclerosis-related adult human cells: potential targets to regulate monocyte/macrophage chemotaxis. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2009. 109. 258P-258P
Aiji Sakamoto, Hatsue Ishibashi-Ueda, Yuka Sugamoto, Yuka Tokunaga, Tsuyoshi Yoshimuta, Takeo Higashikata, Hitoshi Ogino, Masaaki Kawashiri, Kunimasa Yagi, Yoshiyu Takeda, et al. Expression and Function of Ephrin/Eph Family Genes in Atherosclerosis-Related Adult Human Cells: From Aspect of Chemotaxis. CIRCULATION. 2008. 118. 18. S468-S469
Aiji Sakamoto, Hatsue Ishibashi-Ueda, Yuka Sugamoto, Takeo Higashikata, Susumu Miyamoto, Masa-Aki Kawashiri, Kunimasa Yagi, Tetsuo Konno, Kenshi Hayashi, Noboru Fujino, et al. Expression and function of ephrin-B1 and its cognate receptor EphB2 in human atherosclerosis: from an aspect of chemotaxis. Clinical science (London, England : 1979). 2008. 114. 10. 643-50
Aiji Sakamoto, Hatsue Ueda, Tsuyoshi Yoshimuta, Yuka Sugamoto, Masakazu Yamagishi. Ephrin-B1 and its cognate receptor EphB2 are expressed on normal adult arterial endothelium and both inhibit monocyte chemotaxis: New molecular insight into atherogenesis. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2007. 103. 94P-94P

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Patents (6)：

拡張型心筋症の原因となる新規点突然変異を有するデスミン遺伝子
ハムスターのβB1-クリスタリン遺伝子、及びそのスプライシングの制御方法
眼皮膚白子症1Bの原因遺伝子とその応用
デルターサルコグリカン遺伝子の単独欠損ハムスター
Desmin Gene Having Novel Point Mutation Causative of Dilated Cardiomyopathy

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Lectures and oral presentations (3)：

動脈硬化発症に関連する成人細胞におけるエフォリンとその受容体群の発現と機能:単球・マクロファージの化学遊走に対する新知見
(第31回日本分子生物学会年会第81回日本生化学会大会合同大会 2008)
Ephrin/Eph family genes in atherosclerosis-related adult human cells: potential targets to regulate monocyte/macrophage chemotaxis
(MipTec 2008: The Leading European Event for Drug Discovery 2008)
Expression and Function of ephrin/Eph Family Genes in Atherosclerosis-related Adult Human Cells: From Aspect of Chemotaxis
(American Heart Association scientific sessions 2008 2008)

Works (1)：

PRESTO さきがけ研究21 科学技術振興事業団

Professional career (1)：

医学博士 (東京大学)

Association Membership(s) (8)：

国際人名録協会(International Who's Who Historical Society) , 国際循環器病学会 (International Academy of Cardiovascular Sciences) , 国際心臓病学会 (International Society for Heart Research) , 米国心臓病学会(American Heart Association) , 米国人類遺伝学会American Society of Human Genetics , 日本循環器学会 , 日本薬理学会 , 日本分子生物学会

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