Rchr
J-GLOBAL ID：200901062080689334   Update date: Jun. 21, 2024

Nakazawa Takanobu

Nakazawa Takanobu
Affiliation and department：
Tokyo University of Agriculture

About Tokyo University of Agriculture


Research field  (5)： Pharmacology ,  Psychiatry ,  Developmental biology ,  Molecular biology ,  Neuroscience - general
Research keywords  (11)： 精神疾患モデルマウス ,  自閉スペクトラム症 ,  iPS細胞 ,  統合失調症 ,  包括脳ネットワーク ,  シグナル伝達 ,  脳・神経 ,  p250GAP ,  チロシンリン酸化 ,  TCGAP ,  NMDA受容体
Research theme for competitive and other funds  (21)：
  • 2022 - 2024 Molecular analysis of the effects of environmental factors on higher brain function using iPSC technology and mice
  • 2021 - 2024 Modeling autism spectrum disorders with iPSC derived from patients and model mice
  • 2020 - 2024 Development of the integrated therapeutic strategy aiming toward drug discovery and pharmacotherapy for treatment-resistant schizophrenia
  • 2021 - 2023 Modeling psychiatric disorders with iPSC derived from patients
  • 2018 - 2023 Identification and characterization of brain disorder-related singularity cells by whole-brain imaging
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Papers (111)：
  • Kohei Kitagawa, Tomoya Takemoto, Kaoru Seiriki, Atsushi Kasai, Hitoshi Hashimoto, Takanobu Nakazawa. Socially activated neurons in the anterior cingulate cortex are essential for social behavior in mice. Biochemical and Biophysical Research Communications. 2024. 150251-150251
  • Satoshi Asano, Ami Ono, Kaede Baba, Teru Uehara, Kotaro Sakamoto, Atsuko Hayata-Takano, Takanobu Nakazawa, Souichi Yanamoto, Kotaro Tanimoto, Hitoshi Hashimoto, et al. Blockade of vasoactive intestinal peptide receptor 2 (VIPR2) signaling suppresses cyclin D1-dependent cell-cycle progression in MCF-7 cells. Journal of pharmacological sciences. 2024. 154. 3. 139-147
  • Rei Yokoyama, Yukio Ago, Hisato Igarashi, Momoko Higuchi, Masato Tanuma, Yuto Shimazaki, Takafumi Kawai, Kaoru Seiriki, Misuzu Hayashida, Shun Yamaguchi, et al. (R)-ketamine restores anterior insular cortex activity and cognitive deficits in social isolation-reared mice. Molecular psychiatry. 2024
  • Rei Yokoyama, Momoko Higuchi, Wataru Tanabe, Shinji Tsukada, Hisato Igarashi, Kaoru Seiriki, Takanobu Nakazawa, Atsushi Kasai, Yukio Ago, Hitoshi Hashimoto. Long-lasting anti-despair and anti-anhedonia effects of (S)-norketamine in social isolation-reared mice. Journal of pharmacological sciences. 2024. 154. 2. 72-76
  • Yumi Hirato, Kaoru Seiriki, Leo Kojima, Shohei Yamada, Hiroki Rokujo, Tomoya Takemoto, Takanobu Nakazawa, Atsushi Kasai, Hitoshi Hashimoto. Clozapine Induces Neuronal Activation in the Medial Prefrontal Cortex in a Projection Target-Biased Manner. Biological & pharmaceutical bulletin. 2024. 47. 2. 478-485
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MISC (52)：
  • 中井悠花, 島崎雄人, 植野寛貴, 北川航平, 大久保仁, 勢力薫, 中澤敬信, 中澤敬信, 中澤敬信, 橋本均, et al. 自閉スペクトラム症モデルPOGZWT/Q1038Rマウスの大脳皮質の発生過程における雌雄差. 次世代を担う若手のための創薬・医療薬理シンポジウムプログラム・要旨集. 2023. 2023
  • 中井悠花, 島崎雄人, 植野寛貴, 北川航平, 大久保仁, 勢力薫, 中澤敬信, 中澤敬信, 中澤敬信, 橋本均, et al. 自閉スペクトラム症モデルPOGZWT/Q1038Rマウスの大脳皮質の発生過程における雌雄差. 生体機能と創薬シンポジウム要旨集. 2023. 2023
  • 竹本智哉, 馬場優志, 北川航平, 永安一樹, 永安一樹, 勢力薫, 勢力薫, 早田敦子, 早田敦子, 笠井淳司, et al. ヒト染色体3q29領域欠失を導入した自閉スペクトラム症モデルマウスの社会性行動異常はオキシトシンにより回復する. 日本薬理学雑誌. 2022. 157. Supplement
  • 馬場優志, 勢力薫, 近藤百香, 北川航平, 竹本智哉, 笠井淳司, 吾郷由希夫, 吾郷由希夫, 永安一樹, 永安一樹, et al. ヒト染色体3q29欠失モデルマウスを用いた精神疾患の分子病態研究. 日本薬理学雑誌. 2021. 156. Supplement
  • 近藤百香, 栗生俊彦, 馬場優志, 北川航平, 竹本智哉, 永安一樹, 永安一樹, 山森英長, 山森英長, 安田由華, et al. 3q29領域欠失変異を有する精神疾患患者のiPS精神細胞の機能解析. 日本薬理学雑誌. 2021. 156. Supplement
ｍore...
Professional career (1)：
  • 博士(医学) (東京大学)
Work history (13)：
  • 2020/04 - 現在 Tokyo University of Agriculture
  • 2016/04 - 2020/03 Osaka University Graduate School of Dentistry
  • 2013/09 - 2016/03 Osaka University Graduate School of Pharmaceutical Sciences, Drug Innovation Center
  • 2011/06 - 2013/08 The University of Tokyo Graduate School of Medicine
  • 2005/02 - 2011/05 The University of Tokyo The Institute of Medical Science, Division of Oncology
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Awards (1)：
  • 2015/06 - 大阪大学 大阪大学総長奨励賞
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