Rchr
J-GLOBAL ID:200901062303787090   Update date: Jan. 30, 2024

Atsushi Sanbe

サンベ アツシ | Atsushi Sanbe
Affiliation and department:
Homepage URL  (1): https://www.imu-pharm.jp
Research field  (1): Pharmacology
Research keywords  (4): Transgenic mouse / Knockout mouse ,  疾患モデル ,  薬理学 ,  循環器薬理学
Research theme for competitive and other funds  (4):
  • 2013 - 2016 New therapeutic approach of myofibrillar myopathy by mitochondrial protection
  • 2012 - 2015 Relationship between SGLT1 and ventricular arrhythmia
  • 2009 - 2011 Development of new therapeutic strategy for rescuing cardiomyopathy via inhibition of protein aggregation
  • 2007 - 2008 Development of new therapeutic strategy for rescuing cardiomyopathy using small heat shock proteins
Papers (124):
  • Atsushi Sanbe, Yui Inomata, Naoko Matsushita, Yohei Sawa, Chizuru Hino, Hinano Yamazaki, Kei Takanohashi, Natsuko Takahashi, Rieko Higashio, Hideki Tsumura, et al. Modification of cardiac disease by transgenically altered histone deacetylase 6. Biochemical and Biophysical Research Communications. 2022. 631. 48-54
  • Nanae Ishida, Maki Saito, Sachiko Sato, Yu Tezuka, Atsushi Sanbe, Eiichi Taira, Masamichi Hirose. Mizagliflozin, a selective SGLT1 inhibitor, improves vascular cognitive impairment in a mouse model of small vessel disease. Pharmacology Research & Perspectives. 2021. 9. 5
  • Yohei Sawa, Naoko Matsushita, Sachiko Sato, Nanae Ishida, Maki Saito, Atsushi Sanbe, Yoshihiro Morino, Eiichi Taira, Mami Obara, Masamichi Hirose. Chronic HDAC6 Activation Induces Atrial Fibrillation Through Atrial Electrical and Structural Remodeling in Transgenic Mice. International heart journal. 2021. 62. 3. 616-626
  • Tanaka U, Kurosaka D, Murai K, Hashizume K, Sanbe A. Rho/myocardin-related transcription factor A (MRTF-A) pathway plays an important role in TGF-β-induced epithelial mesenchymal transition in retinal pigment epithelial cells. Journal of Iwate Medical Association. 2020. 72. 217-230
  • Toshihiro Yamaguchi, Tomokazu S Sumida, Seitaro Nomura, Masahiro Satoh, Tomoaki Higo, Masamichi Ito, Toshiyuki Ko, Kanna Fujita, Mary E Sweet, Atsushi Sanbe, et al. Cardiac dopamine D1 receptor triggers ventricular arrhythmia in chronic heart failure. Nature communications. 2020. 11. 1. 4364-4364
more...
MISC (72):
Books (4):
  • 薬物治療学 - 薬学テキストシリーズ
    朝倉書店 2020
  • 「薬系薬理学書」
    南江堂 2018
  • 「薬学用語辞典」
    日本薬学会 編 東京化学同人社 2012
  • 「発生学的研究法:モデル動物マウス」「先天性心疾患を理解するための臨床心臓発生学」
    メジカルビュー社 p44-49 2007
Lectures and oral presentations  (40):
  • HDAC6 and Cardiac disease
    (2021)
  • Effect of Bcl-2 associated athanogene (BAG) 3 on cardiac disease in alpha-B crystallin (CryAB) R120G transgenic (TG) mouse.
    (2020)
  • Effect of chloroquine treatment on cardiac function as well as cardiac atrial natriuretic peptide level in Bcl-2-associated athanogene (BAG) 3 transgenic mice
    (第92回日本薬理学会年会 大阪 2019)
  • Bcl-2 associated athanogene (BAG)3による心筋タンパク質の分解調節
    (第138回日本薬学会年会 金沢 2018)
  • Functional role of Bcl-2-associated athanogene (BAG) 3 as a regulator of Bak1 protein level in N1E115 cells.
    (18th World Congress of Basic and Clinical Pharmacology, PO4-1-118, Kyoto 2018)
more...
Education (2):
  • 1990 - 1995 Tokyo University of Pharmacy and Life Sciences
  • - 1990 Tokyo University of Pharmacy and Life Sciences School of Pharmacy School of Pharmacy
Professional career (1):
  • 薬学博士 (東京薬科大学)
Work history (8):
  • 2018/04 - 現在 Iwate Medical University School of Pharmacy
  • 2014/04 - 2018/03 Iwate Medical University School of Pharmacy
  • 2010/04 - 2014/03 Iwate Medical University School of Pharmacy
  • 2005/06 - 2010/03 国立成育医療センター研究所薬剤治療研究部 実験薬理室 室長
  • 2004/10 - 2005/05 シンシナティ大 / シンシナティ小児病院 医学部 分子心血管生物学部門 アシスタントプロフェッサー
Show all
Awards (1):
  • 2005/11 - 日本循環薬理学会 Young Investigator Award CryAB R120G心筋症病態へのアミロイドオリゴマーの関与
Association Membership(s) (4):
日本薬学会 ,  アメリカ心臓協会(AHA) ,  日本循環薬理学会 ,  日本薬理学会
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