Research field (2)：
Applied biofunctional and bioprocess engineering
, Polymer chemistry
Research theme for competitive and other funds (11)：
2021 - 2024 人工代謝系構築による微生物ポリエステルの生合成法開発と材料物性評価
2019 - 2022 Utilization of gas mixture with low hydrogen content for microbial carbon dioxide fixation
2015 - 2018 Cofactor supply for bacterial cell growth and polyhydroxyalkanoate synthesis concomitant with enzymatic oxidation of phosphite
2013 - 2016 Synthesis of ultra-high-molecular-weight microbial polyesters and development of high-tensile-strength and high-modulus fibers by ultra-stretching technique
2013 - 2016 Characterization of the catalytic center of a novel PHA synthase from Halomonas spp.
2011 - 2014 Reduction mechanism of polyhydroxyalkanoate (PHA) molecular weight by class IV PHA synthase
2011 - 2013 Microbial synthesis of polyhydroxyalkanoate bearing phenyl and phenylalkyl side groups
2008 - 2010 Nano-magnetic sensing system for biomedical devices
2007 - 2009 Study on bio-polyester synthesis from recycled alkenoic acids
2003 - 2004 合目的高分子物性を有するバイオポリエステルの微生物合成
2000 - 2002 代謝工学的手法を用いた高性能バイオポリエステルの創製
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Papers (50)：
Ramamoorthi M Sivashankari, Maierwufu Mierzati, Yuki Miyahara, Shoji Mizuno, Christopher T. Nomura, Seiichi Taguchi, Hideki Abe, Takeharu Tsuge. Exploring Class I polyhydroxyalkanoate synthases with broad substrate specificity for polymerization of structurally diverse monomer units. Frontiers in Bioengineering and Biotechnology. 2023. 11
Lucas Vinicius Santini Ceneviva, Maierwufu Mierzati, Yuki Miyahara, Christopher T Nomura, Seiichi Taguchi, Hideki Abe, Takeharu Tsuge. Poly(3-mercapto-2-methylpropionate), a Novel α-Methylated Bio-Polythioester with Rubber-like Elasticity, and Its Copolymer with 3-hydroxybutyrate: Biosynthesis and Characterization. Bioengineering (Basel, Switzerland). 2022. 9. 5
Saki Goto, Yuki Miyahara, Seiichi Taguchi, Takeharu Tsuge, Ayaka Hiroe. Enhanced Production of (R)-3-Hydroxybutyrate Oligomers by Coexpression of Molecular Chaperones in Recombinant Escherichia coli Harboring a Polyhydroxyalkanoate Synthase Derived from Bacillus cereus YB-4. Microorganisms. 2022. 10. 2
Tetsuo Sakurai, Shoji Mizuno, Yuki Miyahara, Ayaka Hiroe, Seiichi Taguchi, Takeharu Tsuge. Optimization of Culture Conditions for Secretory Production of 3-Hydroxybutyrate Oligomers Using Recombinant Escherichia coli. Frontiers in bioengineering and biotechnology. 2022. 10. 829134-829134
Manami Ishii-Hyakutake, Tetsuo Sakurai, Takeharu Tsuge. Screening Method for Polyhydroxyalkanoate Synthase Mutants Based on Polyester Degree of Polymerization Using High-Performance Liquid Chromatography. Microorganisms. 2021. 9. 9
Life cycle inventory analysis of bio-based polyester production by genetically engineered bacteria from renewable carbon sources
(2003)
Life cycle inventory analysis of bio-based polyester production by genetically engineered bacteria from renewable carbon sources
(2003)
Education (1)：
- 1995 Kyushu University School of Agriculture
Professional career (1)：
Doctor of Agriculture (Kyushu University)
Work history (8)：
2005 - 2009 :Tokyo Institute of Technology Associate Professor
2005 - 2009 :東京工業大学 講師
2009 - -:Tokyo Institute of Technology Associate Professor
2009 - -:東京工業大学 准教授
2002 - 2005 :Tokyo Institute of Technology Research Associate
2002 - 2005 :東京工業大学 助手
2000 - 2002 :RIKEN Institute Special Postdoctoral Researcher
2000 - 2002 :理化学研究所 基礎科学特別研究員
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Awards (4)：
2015 - 高分子学会 旭化成賞
2008 - Encouragement Award of the Society for Biotechnology, Japan (Terui Award)
2008 - 東工大挑戦的研究賞
2008 - 生物工学奨励賞(照井賞)
Association Membership(s) (10)：
and Agrochemistry
, Biotechnology
, Japan Society for Bioscience
, The Society for Bioscience and Bioengineering
, The Society of Polymer Science
, エコマテリアル研究会
, バイオインダストリー協会
, 日本農芸化学会
, 日本生物工学会
, 高分子学会
