Rchr
J-GLOBAL ID：200901062839500746
Update date: Feb. 01, 2024
Isobe Ken'ichi
イソベ ケンイチ | Isobe Ken'ichi
Affiliation and department：
Job title：
教授
Research field (3)：
Nutrition and health science
, Cell biology
, Immunology
Research keywords (3)：
nutrition
, GADD34
, Aging
Research theme for competitive and other funds (23)：
- 2019 - 2022 GADD34による老化関連疾患の制御メカニズムの解析
- 2016 - 2019 Stress responsive GADD34 and metabolic syndrome
- 2013 - 2017 Age-related diseases analyzed by ER stresses and immune functions using murine models including iPSCs
- 2010 - 2013 Analysis of tissue failure and treatment by iPSCs
- 2011 - 2013 Effects of transplantation of neural crest cells derived from iPS cells on diabetic polyneuropathy in mice
- 2007 - 2009 Host responses to stress and progression to disease
- 2004 - 2004 ストレス防御系の破綻としての癌発生に関する研究
- 2003 - 2004 ストレス防御系の破綻としての癌発生に関する研究
- 2003 - 2004 ERストレス応答におけるGADD34蛋白の役割
- 2002 - 2004 ストレス防御系の破綻としての癌発生に関する研究
- 2001 - 2001 ストレス防御系の破綻としての癌発生に関する研究
- 1995 - 1996 Gene therapy of gastrointestinal cancer using adenoviral vector
- 1995 - 1996 Basic fibroblast growth factor (bFGF) requires heparan sulfate (HS) that contains bFGF-binding domains for regulating gllomerular cell apoptosis (AP)
- 1994 - 1995 Role of Glial Inducible Nitric Oxide Synthase (iNOS) in Focal Brain Injury
- 1994 - 1995 Establishment of Transgenic Pig for Organ Xenotransplantation
- 1993 - 1995 Study of Xenotransplatation Using Gene Engineering Technique
- 1993 - 1993 トランスジェニックマウス発がん個体において有効な免疫遺伝子治療法開発のための基礎的研究
- 1991 - 1991 がん遺伝子トランスジェニックマウス前がん段階の免疫調節による発がんの制御
- 1991 - 1991 CEAトランスジェニックマウスにおけるがん細胞の接着と転移に関する研究
- 1990 - 1991 Melanovytic tumor development in transgenic mice carrying the ret oncogene
- 1990 - 1990 メラノ-マ好発系トランスジェニックマウスにおけるがん発生初期段階の免疫反応の解析
- 1988 - 1989 Human CD4 gene transgenic mouse as an AIDS model animal.
- 1986 - 1986 Thy-1抗原の特異な免疫活性の分子生物学的解析
Show all
Papers (250)：
-
Kentaro Oh-Hashi, Naoki Sugiura, Fumimasa Amaya, Ken-Ichi Isobe, Yoko Hirata. Functional validation of ATF4 and GADD34 in Neuro2a cells by CRISPR/Cas9-mediated genome editing. Molecular and cellular biochemistry. 2018. 440. 1-2. 65-75
-
Naomi Nishio, Tadao Hasegawa, Ichiro Tatsuno, Masanori Isaka, Ken-Ichi Isobe. Female GADD34 mice develop age-related inflammation and hepatocellular carcinoma. Geriatrics & gerontology international. 2017. 17. 12. 2593-2601
-
Ken-Ichi Isobe, Naomi Nishio, Tadao Hasegawa. Immunological aspects of age-related diseases. World journal of biological chemistry. 2017. 8. 2. 129-137
-
Qiuna Du, Naotake Tsuboi, Yiqin Shi, Sachiko Ito, Yutaka Sugiyama, Kazuhiro Furuhashi, Nobuhide Endo, Hangsoo Kim, Takayuki Katsuno, Shin'ichi Akiyama, et al. Transfusion of CD206+ M2 Macrophages Ameliorates Antibody-Mediated Glomerulonephritis in Mice. The American journal of pathology. 2016. 186. 12. 3176-3188
-
Ken-Ichi Isobe. Mechanism of immune aging. Nihon rinsho. Japanese journal of clinical medicine. 2016. 74. 9. 1497-1501
ｍore...
MISC (19)：
-
Masaki Kondo, Hideki Kamiya, Tomohide Hayami, Mikio Motegi, Saeko Noda, Tetsuji Okawa, Tatsuhito Himeno, Keiko Naruse, Yoshiro Kato, Ken-Ichi Isobe, et al. Transplantation of Neural Crest Cells Derived from 3D Dermal Stem/Progenitor Cells Improves Diabetic Polyneuropathy in Mice. DIABETES. 2016. 65. A1-A1
-
Masaki Kondo, Hideki Kamiya, Tatsuhito Himeno, Tetsuji Okawa, Keiko Naruse, Yoshiro Kato, Ken-Ichi Isobe, Jiro Nakamura. Transplantation of Neural Crest Cells Derived from 3D-aggregated Dermal Stem Cells Improves Diabetic Polyneuropathy in Mice. DIABETES. 2015. 64. A157-A158
-
Masaki Kondo, Hideki Kamiya, Tatsuhito Himeno, Tetsuji Okawa, Keiko Naruse, Yoji Hamada, Naoko Nishio, Sachiko Ito, Yutaka Oiso, Ken-Ichi Isobe, et al. Transplantation of Induced Neural Crest Cells from Spheroidal Dermal Stem Cells Improves Diabetic Polyneuropathy in Mice. DIABETES. 2014. 63. A146-A146
-
Masaki Kondo, Hideki Kamiya, Tatsuhito Himeno, Tetsuji Okawa, Jiro Kato, Atsushi Hujiya, Yoji Hamada, Keiko Naruse, Naomi Nishio, Sachiko Ito, et al. Transplantation of Induced Neural Crest Cells from Spheroidal Dermal Stem Cells Improves Diabetic Polyneuropathy in Mice. DIABETES. 2013. 62. A146-A146
-
Masaki Kondo, Hideki Kamiya, Tatsuhito Himeno, Jiro Kato, Tetsuji Okawa, Atsushi Fujiya, Keiko Naruse, Yoji Hamada, Naomi Nishio, Sachiko Ito, et al. Transplantation of Neural Progenitor-Like Cells Derived from Spheroidal Dermal Cells Improves Diabetic Polyneuropathy in Mice. DIABETES. 2012. 61. A20-A20
ｍore...
Books (3)：
-
臨床医科学
三恵社 2016 ISBN:9784864875042
-
Stem cell therapy
Transworld Research Network 2010 ISBN:9788178955025
-
Induction of tumor resistance by hybrid cell lines between human acute lymphocytic leukemia cells and mouse myeloma cells
[s.n.]
Work history (1)：
Return to Previous Page
