Rchr
J-GLOBAL ID:200901062887501991
Update date: Sep. 12, 2024
Mukoyama Masashi
ムコウヤマ マサシ | Mukoyama Masashi
Affiliation and department:
Job title:
Professor
Homepage URL (1):
http://www.kumadai-nephrology.com/
Research field (2):
Metabolism and endocrinology
, Nephrology
Research keywords (6):
内分泌代謝学
, 高血圧
, 腎臓内科学
, Endocrinology and Metabolism
, Hypertension
, Nephrology
Research theme for competitive and other funds (29):
- 2024 - 2027 The role of osmoprotective transcription factor NFAT5 in the progression of aging-associated kidney disease.
- 2022 - 2025 セリンプロテアーゼによる尿濃縮メカニズムの解明
- 2021 - 2024 Investigation of the role of NFAT5 in the regulation of renal interstitial microenviroment and blood pressure
- 2020 - 2023 Study on the mechanisms of kidney disease progression and their regulation: roles of chronic inflammation and humoral mediators
- 2019 - 2022 Verification of the utility of urinary thrombin levels as a novel urinary biomarker for differential diagnosis of renal diseases
- 2018 - 2021 Investigation of the role of NFAT5 in chronic kidney injury.
- 2017 - 2020 Role of local inflammation in the kidney for the development and progression of chronic kidney disease and its regulation toward novel therapeutic strategy
- 2017 - 2019 Elucidation of the role of MRP8 through inflammation and ER stress in metabolic syndrome related nephropathy
- 2017 - 2019 アンモニアトランスポーター(Rhcg)制御による新規糖尿病性腎症治療薬の開発
- 2015 - 2019 Effects of thermal preconditioning on cisplatin nephropathy
- 2015 - 2018 Elucidation of the physiological role of serine protease hepsin in the kidney.
- 2015 - 2018 Suppressive effects of mild sauna stimulation on chronic kidney disease progression
- 2014 - 2017 Renoprotecion of acetazolamide and canagliflozin
- 2014 - 2017 Roles of humoral factors and organ-organ or cell-cell communications in the development and progression of metabolic kidney diseases
- 2009 - 2014 Physiological Function of Hormones Derived from Mesenchymal Cells and Its Failure
- 2011 - 2013 Role of humoral factors in the development and progression of metabolic syndrome-related kidney diseases
- 2008 - 2010 Translational research and clinical application of the natriuretic peptide system in the kidney.
- 2005 - 2006 Study on Mechanisms for Progression and Regression of Diabetic Glomerular Injury and Role of Novel Humoral Factors
- 2001 - 2002 Protective Role of the Natriuretic Peptide System in Tissue Injury and Remodeling
- 1998 - 2002 Molecular Study on Physiological and Clinical Significance of Adrenomedullin
- 1999 - 2000 Multi-center research on molecular mechanism of cardiovascular remodeling using genetically-engineered animals
- 1999 - 2000 Pathophysiological and Clinical Significance of Renal Prostanoid Receptors
- 1998 - 2000 Clinical implication of cardiovascular hormones
- 1997 - 1998 Molecular Studies of Prostanoid Receptors in the Kidney
- 1997 - 1998 Molecular and Clinical Study of Renal Angiotensin and Adrenomedullin Systems
- 1996 - 1996 腎糸球体障害の発症・進展におけるプロスタノイド受容体の病態生理的意義
- 1996 - 1996 アンジオテンシン受容体ファミリーの臨床的意義に関する発生学的・分子生物学的研究
- 1996 - 1996 Molecular and Clinical Study of Cardiovascular Hormones
- 1995 - 1995 アンジオテンシン受容体サブタイプの生理的並びに臨床的意義に関する分子生物学的研究
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Papers (389):
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Yukiko Yasuoka, Yuichiro Izumi, Takashi Fukuyama, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu, Noritada Kobayashi, Masayoshi Nanami, Yoshitaka Shimada, Yasushi Nagaba, et al. Tubular Endogenous Erythropoietin Protects Renal Function against Ischemic Reperfusion Injury. International journal of molecular sciences. 2024. 25. 2
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Makoto Ono, Yuichiro Izumi, Kosuke Maruyama, Yukiko Yasuoka, Akiko Hiramatsu, Jose Aramburu, Cristina López-Rodríguez, Hiroshi Nonoguchi, Yutaka Kakizoe, Masataka Adachi, et al. Characterization of gene expression in the kidney of renal tubular cell-specific NFAT5 knockout mice. American journal of physiology. Renal physiology. 2023
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Yoshikazu Miyasato, Jun Morinaga, Hideki Inoue, Yushi Nakayama, Masataka Adachi, Yuichiro Izumi, Yutaka Kakizoe, Teruhiko Mizumoto, Terumasa Nakagawa, Daisuke Fujimoto, et al. Association between prognostic nutritional index and peritoneal dialysis discontinuation: a retrospective cohort study. Renal Replacement Therapy. 2023. 9. 1
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Hirotaka Fukami, Jun Morinaga, Hironori Nakagami, Hiroki Hayashi, Yusuke Okadome, Eiji Matsunaga, Tsuyoshi Kadomatsu, Haruki Horiguchi, Michio Sato, Taichi Sugizaki, et al. Efficacy and safety in mice of repeated, lifelong administration of an ANGPTL3 vaccine. npj Vaccines. 2023. 8. 1
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Yasunobu Iwata, Qinyuan Deng, Yutaka Kakizoe, Terumasa Nakagawa, Yoshikazu Miyasato, Miyuki Nakagawa, Kayo Nishiguchi, Yu Nagayoshi, Yuki Narita, Yuichiro Izumi, et al. A Serine Protease Inhibitor, Camostat Mesilate, Suppresses Urinary Plasmin Activity and Alleviates Hypertension and Podocyte Injury in Dahl Salt-Sensitive Rats. International journal of molecular sciences. 2023. 24. 21
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MISC (332):
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桑原 孝成, 向山 政志. 【高血圧の最近の治療戦略-近未来の展望】治療薬解説 ARNI(サクビトリルバルサルタン)の高血圧治療戦略における位置づけ. カレントテラピー. 2023. 41. 5. 470-475
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向山 政志. 【高血圧の最新診断・治療update-診断・治療の最新動向-】アンジオテンシン受容体ネプリライシン阻害薬(ARNI). 日本臨床. 2023. 81. 1. 151-156
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向山 政志. 【高血圧診療の百年の変遷と新たな展開】他の疾患を合併する高血圧 腎疾患. 臨牀と研究. 2023. 100. 1. 57-61
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向山 政志. 【早朝・夜間高血圧の徹底管理-パーフェクト24時間血圧コントロールを目指して-】CKDと夜間高血圧. カレントテラピー. 2022. 40. 9. 873-877
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泉 裕一郎, 向山 政志. 【腎疾患におけるサルコペニア・フレイルの病態と臨床】サルコペニア・フレイルと代謝性アシドーシス. 腎臓内科. 2022. 16. 1. 46-52
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Books (2):
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腎機能に応じた投与戦略 : 重篤な副作用の防ぎかた
医学書院 2016 ISBN:9784260028646
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病態から学ぶ新腎臓内科学
診断と治療社 2011 ISBN:9784787818904
Education (4):
- - 1990 Kyoto University
- - 1990 Kyoto University Graduate School, Division of Medicine Internal Medicine
- - 1983 Kyoto University Faculty of Medicine Department of Medical Science
- - 1983 Kyoto University Faculty of Medicine Faculty of Medicine
Professional career (1):
Work history (14):
- 2006 - 2014 Kyoto University Graduate School of Medicine
- 2006 - 2014 Associate Professor
- 2014 - Kumamoto University Faculty of Life Sciences
- 2014 - Professor,Faculty of Life Sciences(Clinical medicine group),Kumamoto University
- 2002 - 2006 Kyoto University Graduate School of Medicine
- 2002 - 2006 Lecturer
- 1995 - 2002 Kyoto University Graduate School of Medicine
- 1995 - 2002 Research Associate
- 1994 - 1995 Kyoto University Hospital
- 1994 - 1995 Medical Staff
- 1991 - 1994 スタンフォード大学医学部心臓血管研究所 研究員
- 1991 - 1994 Researcher
- 1990 - 1991 Kyoto University Graduate School of Medicine
- 1990 - 1991 Researcher
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Association Membership(s) (15):
国際高血圧学会
, 米国内分泌学会
, 国際腎臓学会
, 米国腎臓学会
, 日本循環器学会
, 日本糖尿病学会
, 日本内分泌学会
, 日本高血圧学会
, 日本透析医学会
, 日本腎臓学会
, 日本内科学会
, International Society of Hypertension
, The Endocrine Society
, International Society of Nephrology
, American Society of Nephrology
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