Rchr
J-GLOBAL ID:200901062947375931   Update date: Feb. 14, 2024

Takeo IWATA

イワタ タケオ | Takeo IWATA
Affiliation and department:
Job title: Associate Professor
Research keywords  (3): 内分泌・代謝 ,  内分泌腺腫瘍 ,  肥満
Research theme for competitive and other funds  (27):
  • 2018 - 現在 下垂体腺腫におけるインプリント異常を含むDNAメチル化脱制御の解析
  • 2018 - 現在 D-ドーパクロムトートメラーゼに関連する肥満治療薬の開発戦略
  • 2022 - 2027 ヒト抗肥満創薬を目指した多面的アプローチによる標的分子の探索と機能解析
  • 2021 - 2024 膵β細胞特異的Prss53の分子メカニズム
  • 2018 - 2022 A strategy for the development of anti-obesity drugs related to D-dopachrome tautomerase.
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Papers (50):
  • Noriko Mizusawa, Nagakatsu Harada, Takeo Iwata, Izumi Ohigashi, Mitsuo Itakura, Katsuhiko Yoshimoto. Identification of protease serine S1 family member 53 as a mitochondrial protein in murine islet beta cells. Islets. 2022. 14. 1. 1-13
  • Takahaashi A, Iwata T, Yamashita K. Knockdown of d-dopachrome tautomerase inhibits cell proliferation in human HepG2 cell line. Anticancer Res. 2021. 41. 4077-4082
  • Fukuhara N, Iwata T, Inoshita N, Yoshimoto K, Kitagawa M, Fukuhara H, Tatsushima K, Yamaguchi-Okada M, Takeshita A, Ito J, et al. Immunohistochemistry or Molecular Analysis: Which method is better for subtyping craniopharyngioma?. Endocri Pathol. 2020. in press
  • Marques P, Caimari F, Hernández-Ramírez LC, Collier D, Iacovazzo D, Ronaldson A, Magid K, Lim CT, Stals K, Ellard S, et al. Significant benefits of AIP testing and clinical screening in familial isolated and young-onset pituitary tumors. J Clin Endocrinol Metab. 2020
  • Yuichi Nagata, Naoko Inoshita, Noriaki Fukuhara, Mitsuo Yamaguchi-Okada, Hiroshi Nishioka, Takeo Iwata, Katsuhiko Yoshimoto, Shozo Yamada. Growth hormone-producing pituitary adenomas in childhood and young adulthood: clinical features and outcomes. Pituitary. 2018. 21. 1. 1-9
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MISC (47):
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Books (3):
  • Sodefrin and Related Pheromones.
    Acad Press 2013
  • Pituitary adenomas: Role of cyclin-dependent kinase inhibitors.
    Springer 2013
  • Somatic mutations of the CTNNB1 gene in cribriform-morular variant of papillary thyroid carcinoma.
    Transworld Research Network 2006
Lectures and oral presentations  (9):
  • D-dopachrome tautomeraseはヒト肝がん細胞株HepG2の細胞増殖を促進する
    (第24回バイオ治療法研究会学術集会 2020)
  • 双方向型社会連携教育ISCEに参加した住民に対する「かかりつけ薬剤師」の認知度の変遷
    (日本薬学会第140年会 2020)
  • インスリン抵抗性改善作用を有するアディポカインD-dopachrome tautomeraseの単球・マクロファージにおける機能解析
    (日本薬学会第140年会 2020)
  • アンケート調査から見える「かかりつけ薬剤師」制度が浸透しない要因に関する考察
    (日本薬学会第140年会 2020)
  • 頭蓋咽頭腫の病理亜型診断の方法と意義
    (第29回臨床内分泌代謝Update 2019)
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Works (9):
  • Possible existence of processing enzymes generating sodefrin molecule in the abdominal gland.
    Ishizuka Y, <U>Iwata T</U>, Conlon JM, Toyoda F, Nakada T, Yamamoto K, Kikuyama S 2004 -
  • Detection of sodefrin-responsive cell in the newt vomeronasal epithelium by calcium imaging.
    <U>Iwata T</U>, Yada T, Shioda S, Toyoda F, Kikuyama S 2004 -
  • Regional and individual differences in the gene expression of sodefrin variant in the abdominal gland of <I>Cynops pyrrhogaster</I>.
    <I>Iwata T</I>, Conlon JM, Toyoda F, Kikuyama S 2002 -
  • Expression of parbalbmin isoforms in the postmetamorphic bullfrog,<I> Rana catesbeiana.</I>
    Hasebe T, <I>Iwata T</I>, Yamamoto K, Obinata T, Kikuyama S 2002 -
  • Sodefrin-like pheromone in the abdominal gland of <I>Cynops ensicauda</I>: molecular cloning and purification.
    <U>Iwata T</U>, Yamamoto K, Kawahara G, Hayashi T, Ohe Y, Hayashi H, Toyoda F, Kikuyama S 2001 -
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Education (3):
  • 1998 - 2001 Waseda University
  • 1996 - 1998 Waseda University
  • 1992 - 1996 Waseda University School of Education Department of Biology
Professional career (1):
  • Ph.D. (Waseda University)
Work history (11):
  • 2018/05 - 現在 Niigata University of Pharmacy and Applied Life Sciences Department of of Pharmacy
  • 2018/05/01 - 現在 Niigata University of Pharmacy and Applied Life Sciences Faculty of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences
  • 2015/04 - 2018/04 Assistant Professor
  • 2015/04 - 2018/04 Assistant Professor
  • 2006/04 - 2015/03 Assistant Professor
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Awards (3):
  • 2014 - バイオビジネス・アワードJAPAN 彩都賞 新規抗肥満分子標的とそのスクリーニング技術
  • 2011 - 高田充歯科基礎医学奨励賞 新しいタイプの癌抑制蛋白質パラフィブロミンの機能解析
  • 2006 - 日本内分泌病理学会若手奨励賞 癌抑制因子パラフィブロミンはSV40 large T抗原存在下では細胞増殖促進に働く
Association Membership(s) (4):
日本臨床内分泌病理学会 ,  日本薬学会 ,  日本肥満学会 ,  日本糖尿病学会
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