2020 - 2023 Neuroscientific elucidation of the toxic mechanisms of new psychoactive drugs in the brain's reward system
2018 - 2021 Toxicities and pharmacokinetics of new chemical structures of designer drugs, and their prediction in humans
2017 - 2020 Molecular pathology of fatty liver disease learned from the muscle-liver axis
2016 - 2019 Evaluation of the neurochemical effects of diphenidine, a new psychoactive substance, on the dopaminergic reward system by using rat brain microdialysis
2016 - 2018 Development of neuro and cardiac toxicity models considering disposition and interactions of toxic chemicals
2015 - 2018 Structure-Activity Relationship and Mechanistic Studies on Sodium 4-phenylbutyrate and its derivatives
2014 - 2016 Prediction of metabolism and metabolome analysis of designer drugs using humanized liver mice
Hiroaki Konishi, Takeshi Saito, Shuichiro Takahashi, Hiroki Tanaka, Katsuhiro Okuda, Hiroaki Akutsu, Tatsuya Dokoshi, Aki Sakatani, Keitaro Takahashi, Katsuyoshi Ando, et al. The butyrate derived from probiotic Clostridium butyricum exhibits an inhibitory effect on multiple myeloma through cell death induction. Scientific reports. 2025. 15. 1. 11919-11919
Masaru Asari, Yuta Takahashi, Ryo Namba, Chisato Hoshina, Kanae Mori, Katsuhiro Okuda, Keiko Shimizu. Second- and third-degree kinship analysis by NGS-based SNP genotyping and evaluation of 2045-SNP performance on limited or degraded DNA. Forensic Science International. 2025. 367. 112346-112346
Ayaka Yasuda, Wataru Murase, Atsuhito Kubota, Naoto Uramaru, Katsuhiro Okuda, Ryo Hakota, Atsuko Ikeda, Hiroyuki Kojima. Effects of di-(2-ethylhexyl) phthalate and its metabolites on transcriptional activity via human nuclear receptors and gene expression in HepaRG cells. Toxicology in vitro : an international journal published in association with BIBRA. 2024. 101. 105943-105943
Mihiro Shiga, Masaru Asari, Yuta Takahashi, Shotaro Isozaki, Chisato Hoshina, Kanae Mori, Ryo Namba, Katsuhiro Okuda, Keiko Shimizu. DNA methylation-based age estimation and quantification of the degradation levels of bisulfite-converted DNA. Legal medicine (Tokyo, Japan). 2024. 67. 102336-102336
Evaluation of the effects on the dopaminergic reward system and the blood-brain barrier permeability of diphenidine derivatives using rat brain microdialysis
(Neuroscience 2023)
- 2004 Hiroshima University Graduate School, Division of Medical Sciences
- 2004 Hiroshima University
- 1999 Hiroshima University Faculty of Medicine Institute of Pharmaceutical Sciences
Professional career (1):
博士(薬学) (広島大学)
Work history (6):
2014/04 - 現在 Asahikawa Medical College Assistant Professor
2012/04 - 2014/03 Hiroshima University Research Assistant
2011/01 - 2012/03 Kyushu University Researcher
2010/02 - 2010/10 テンプル大学 心臓血管研究センター 研究員
2007/04 - 2010/01 Hiroshima International University Assistant Professor
2004/04 - 2007/03 Hiroshima International University Research Assistant
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Association Membership(s) (10):
日本法医病理学会
, 日本中毒学会
, 日本犯罪学会
, Japanese Association of Forensic Science and Technology
, 日本法医学会
, 日本法中毒学会
, 日本薬学会
, 日本神経化学会
, Japanese Society for Neurochemistry
, The Pharmaceutical Society of Japan