Rchr

J-GLOBAL ID：200901063606644744 Update date: Jan. 17, 2024

Kuwano Koichi

クワノコウイチ | Kuwano Koichi

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.med.kurume-u.ac.jp/med/micro/

Research field (4)： Allergies and connective tissue disease , Immunology , Virology , Bacteriology

Research keywords (3)：感染防御細菌学免疫学ワクチン抗菌物質 , 感染症 , mycoplasma infection TLR lipoprotein

Research theme for competitive and other funds (10)：

緑膿菌の病原因子プロテアーゼの機能解析
安全なワクチンの開発
新規抗菌剤の開発
マイコプラズマと真核細胞の相互作用解析
Innate Immunityにおける抗菌ペプチドの機能解析

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MISC (68)：

Kida. Y, Shimizu. T, Kuwano. K. An in vivo role for large extracellular protease (LepA) of Pseudomonas aeruginosa: cooperation between LepA and hemolytic phospholipase C (PlcH) contributes to the virulence and growth of P. aeruginosa in mice. Infection and Immunity. 2011
Junichi Taira, Yutaka Kida, Hiroshi Yamaguchi, Koichi Kuwano, Yuichiro Higashimoto, Hiroaki Kodama. Modifications on amphiphilicity and cationicity of unnatural amino acid containing peptides for the improvement of antimicrobial activity against pathogenic bacteria. JOURNAL OF PEPTIDE SCIENCE. 2010. 16. 11. 607-612
Takashi Shimizu, Yutaka Kida, Koichi Kuwano. A triacylated lipoprotein from Mycoplasma genitalium activates NF-kappa B through toll-like receptor 1 (TLR1) and TLR2. INFECTION AND IMMUNITY. 2008. 76. 8. 3672-3678
Yutaka Kida, Yuichiro Higashimoto, Hiroyoshi Inoue, Takashi Shimizu, Koichi Kuwano. A novel secreted protease from Pseudomonas aeruginosa activates NF-kappa B through protease-activated receptors. CELLULAR MICROBIOLOGY. 2008. 10. 7. 1491-1504
Takashi Shimizu, Yutaka Kida, Koichi Kuwano. Ureaplasma parvum lipoproteins, including MB antigen, activate NF-kappa B through TLR1, TLR2 and TLR6. MICROBIOLOGY-SGM. 2008. 154. 5. 1318-1325

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Works (6)：

Ability of apatite to bind to bacteria
2001 -
抗菌ペプチドに対するポリクローナル抗体作製(進行中)
マクロライド系抗菌剤の臨床分離Mycoplasma pneumoniaeに対する評価
抗菌物質ナイシンの実用化開発(継続中)
抗菌物質ナイシンの病原細菌に対する抗菌活性の評価

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Education (2)：

- 1981 Kumamoto University Faculty of Medicine
Kumamoto University School of Medicine School of Medicine

Professional career (2)：

PhD (Tohoku University)
医学博士

Work history (5)：

1992 - 1996 Kurume University medical School, research associate
1996 - - Kurume University medical School, Professor
1991 - 1992 Kurume University medical School, lecturer
1989 - 1991 Kurume University medical School, research assistant
1985 - 1989 Massachusetts Medical School, research assistant

Association Membership(s) (7)：

Amecican Society for Microbiology , 日本医学教育学会 , 日本マイコプラズマ学会 , 日本感染症学会 , 日本ウイルス学会 , 日本免疫学会 , 日本細菌学会

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