Research field (2)：
Pharmacology
, Functional biochemistry
Research keywords (4)：
シグナル伝達
, Gタンパク質
, 受容体
, 一次繊毛
Research theme for competitive and other funds (25)：
2021 - 2024 神経炎症における傷害性アストロサイト一次繊毛の形成と機能の解明
2013 - 2016 Analysis of the regulatory mechanisms of G protein-coupled receptor signaling
2013 - 2015 Gタンパク質シグナル複合体の解析
2011 - 2013 Gタンパク質シグナル複合体の解析
2009 - 2011 Analysis of the novel family of G protein-coupled receptor
2005 - 2010 New research initiatives in the study of G-protein signaling systems integrating cell communication network
2005 - 2009 Identification and analysis of new molecules that regulate G protein signaling
2007 - 2008 Functional analysis of a novel type of G protein-coupled receptor
2007 - 2008 新規活性調節因子による三量体G蛋白質制御機構の構造学的解析
2005 - 2006 Functional analysis of regulatory mechanism of G protein signal network
2005 - 2006 膜ラフトにおけるGタンパク質シグナルの分子制御
2003 - 2005 Proteomic identification of molecules involved in neuronal polarity formation and analysis of their intracellular molecular networks
2004 - 2004 膜ラフトにおけるGタンパク質シグナルの分子制御
2003 - 2004 Study on function and molecular mechanism of G protein signal network
1999 - 2002 細胞内シグナルネットワークにおけるGタンパク質の構造と機能
2000 - 2000 Gタンパク質共役受容体を介する細胞増殖制御シグナルの分子機構
1999 - 1999 Gタンパク質共役受容体を介する細胞増殖制御シグナルの分子機構
1998 - 1998 Gタンパク質共役受容体を介する細胞増殖制御シグナルの分子機構
1994 - 1996 Regulation of neuronal cell ion channels by G proteins
1994 - 1995 Signaling for cell growth regulation and function of heterotrimeric G protein
1994 - 1994 Gタンパク質とエフェクター分子の相互作用
1993 - 1993 Gタンパク質とエフェクター分子の相互作用
1987 - 1989 シグナル伝達に関与するGTP結合タンパク質の構造と機能
Gタンパク質共役受容体を介するシグナル伝達
Signal Transduction Mediated by G Protein Coupled Receptor
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Papers (39)：
Nor Atiqah Muhamad, Kohei Masutani, Shota Furukawa, Shunsuke Yuri, Michinori Toriyama, Chuya Matsumoto, Seiya Itoh, Yuichiro Shinagawa, Ayako Isotani, Manami Toriyama, et al. Astrocyte-Specific Inhibition of the Primary Cilium Suppresses C3 Expression in Reactive Astrocyte. Cellular and Molecular Neurobiology. 2024. 44. 1
Nor Atiqah Binti Muhamad, Shota Furukawa, Sunsuke Yuri, Michinori Toriyama, Kohei Masutani, Chuya Matsumoto, Seiya Itoh, Yuichiro Shinagawa, Ayako Isotani, Manami Toriyama, et al. Astrocyte-specific inhibition of primary cilium functions improves cognitive impairment during neuroinflammation by suppressing A1 astrocyte differentiation. 2023
Toshihiko Fushimi, Tetsuo Kobayashi, Hiroshi Itoh. CEP164-GLI2 association ensures the hedgehog signaling in pancreatic cancer cells. Biochemical and Biophysical Research Communications. 2023. 666. 179-185
Yamanoi Toshihiro, Toriyama Manami, Itoh Hiroshi, Yao Ikuko, Toriyama Michinori. Asef2のRNA結合能を有するスプライシングバリアントの同定と機能解析(Identification and characterization of Asef2 splicing variant bound to RNA). The Journal of Physiological Sciences. 2023. 73. Suppl.1. 133-133
Yusuke Nojima, Manami Toriyama, Kenji Tago, Norikazu Mizuno, Kazuhiro Morishita, Hiroshi Itoh. GPR56 C-terminal fragment mediates signal received by N-terminal fragment of another adhesion GPCR Latrophilin1 in neurons. Genes to cells : devoted to molecular & cellular mechanisms. 2022
Joint Research on Regulatory Mechanism of Ion Channel
1994 -
Education (2)：
- 1986 Hokkaido University
- 1981 Hokkaido University Faculty of Pharmaceutical Sciences Department of Pharmacy
Professional career (1)：
Doctor of Pharmaceutical Science (Hokkaido University)
Work history (7)：
2018 - 現在 Nara Institute of Science and Technology
2001 - 2018 Nara Institute of Science and Technology Graduate School of Biological Sciences Professor
2000 - 2001 The University of Tokyo Graduate School of Agricultural and Life Sciences
1992 - 2000 Tokyo Institute of Technology School of Bioscience and Biotechnology
1989 - 1992 テキサス大学サウスウェスタンメディカルスクール 客員講師
1987 - 1992 The University of Tokyo The Institute of Medical Science
1985 - 1987 日本学術振興会 特別研究員
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Committee career (6)：
2015 - 現在 American Society for Pharmacology and Experimental Therapeutics Editorial and Advisory Board
2017 - 2019 日本生化学会 理事
日本薬理学会 学術評議員
日本学術振興会科学研究費委員会専門委員
日本学術振興会特別研究員等審査会専門委員
文部科学省科学技術・学術審議会専門委員
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Association Membership(s) (7)：
The Japanese Cancer Association
, Japan Neuroscience Society
, 日本薬学会
, 日本分子生物学会
, 日本薬理学会
, 日本生化学会
, American Society for Pharmacology and Experimental Therapeutics
