Rchr
J-GLOBAL ID：200901064410417800
Update date: Sep. 28, 2022
Shimizu Motomu
シミズ モトム | Shimizu Motomu
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Affiliation and department：
, Tokyo Metropolitan Institute of Medical Science Tumor Therapy
About , Tokyo Metropolitan Institute of Medical Science Tumor Therapy
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Job title：
Chief Researcher
Homepage URL (2)：
http://www.rinshoken.or.jp/
,
http://www.rinshoken.or.jp/index-e.html
Research field (1)：
Immunology
Research keywords (18)：
スーパー抗原
, Fas Fasリガンド
, アポトーシス
, IL-27
, 抗腫瘍作用
, 抗腫瘍免疫
, 腫瘍
, 免疫学
, Superantigen
, Chemokine
, Fas ligand
, Fas
, Apoptosis
, IL-27
, Antitumor effect
, Antitumor immunity
, Tumor
, Immunology
Research theme for competitive and other funds (2)：
IL-27、アポトーシス、ケモカインおよびスーパー抗原による抗腫瘍免疫の増強
Inductlon of antitumor Immunity with IL-27, apoptosis, chemokine and superantigen
MISC (20)：
M Shimizu, T Yoshimoto, M Sato, A Matsuzawa, Y Takeda. Frequency and resistance of CD95 (Fas/Apo-1) gene-transfected tumor cells to CD95-mediated apoptosis by the elimination and methylation of integrated DNA. INTERNATIONAL JOURNAL OF CANCER. 2006. 119. 3. 585-592
M Shimizu, T Yoshimoto, M Sato, J Morimoto, A Matsuzawa, Y Takeda. Roles of CXC chemokines and macrophages in the recruitment of inflammatory cells and tumor rejection induced by Fas/Apo-1 (CD95) ligand-expressing tumor. INTERNATIONAL JOURNAL OF CANCER. 2005. 114. 6. 926-935
Motomu Shimizu, Takayuki Yoshimoto, Akio Matsuzawa, Yasutaka Takeda. Modification of tumor cells with Fas (CD95) antigen gene and Fas ligand (CD95L) gene transfection by electroporation for immunotherapy of cancer. Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology. 2003. 25. 1. 79-87
Akio Matsuzawa, Motomu Shimizu, Yasutaka Takeda, Hisashi Nagase, Kazutoshi Sayama, Mikio Kimura. Significant role of Fas ligand-binding but defective Fas receptor (CD95) in lymph node hyperplasia composed of abnormal double-negative T cells. Immunology. 2002. 106. 4. 470-475
Motomu Shimizu, Adriano Fontana, Yasutaka Takeda, Takayuki Yoshimoto, Airo Tsubura, Akio Matsuzawa. Fas/Apo-1 (CD95)-mediated apoptosis of neutrophils with Fas ligand (CD95L)-expressing tumors is crucial for induction of inflammation by neutrophilic polymorphonuclear leukocytes associated with antitumor immunity. Cellular Immunology. 2001. 207. 1. 41-48
ｍore...
Education (4)：
Shinshu University
Tokyo Metropolitan University
Shinsyuu University
Tokyo Metropolitan University
Professional career (1)：
pH.D
Association Membership(s) (3)：
日本免疫学会
, 日本癌学会
, がん分子標的治療研究会
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