Rchr
J-GLOBAL ID：200901065061353898   Update date: Feb. 27, 2024

Seino Kenichiro

セイノ ケンイチロウ | Seino Kenichiro
Affiliation and department：
Hokkaido University Institute for Genetic Medicine

About Hokkaido University Institute for Genetic Medicine


Homepage URL  (1)： http://www.igm.hokudai.ac.jp/byo-ri/Immunobiology-Web/Home.html
Research field  (5)： Respiratory medicine ,  General surgery, pediatric surgery ,  Digestive surgery ,  Experimental pathology ,  Immunology
Research keywords  (30)： NKT細胞 ,  樹状細胞 ,  IBD ,  細胞分化 ,  疾患モデル動物 ,  制御性T細胞 ,  CD25陽性T細胞 ,  α-galactosylceramide ,  細胞分代 ,  INAD ,  アデノウィルスベクター ,  RNAaseプロテクションアッセイ ,  Fas-L ,  免疫抑制 ,  慢性拒絶反応 ,  遺伝子治療 ,  大腸がん ,  ブレオマイシン ,  遺伝子導入 ,  臓器移植 ,  アポトーシス ,  MMP ,  Fas ,  FADD ,  活性酸素 ,  mRNA ,  間質性肺炎 ,  動物実験 ,  肺線維症 ,  免疫抑制剤
Research theme for competitive and other funds  (13)：
  • 2017 - 2020 Studies on the functions of IL-34 and its therapeutic application for multiple melanoma-relative osteolytic disease
  • 2017 - 2019 A study for immune-regulation overcoming allogeneic spacio-temporal barrier using iPS cells
  • 2016 - 2019 Amelioration of experimental autoimmune uveoretinitis with macrophage-like induced pluripotent stem cell-derived suppressor cells
  • 2014 - 2017 Investigation of the anti inflammatory and antifibrotic function of regulatory T cells to establish the immune cell therapy in keloid
  • 2013 - 2016 Elucidating the collapse of immune system against malignant melanoma
Show all
Papers (193)：
  • Haruka Wada, Ryo Otsuka, Wilfred T V Germeraad, Tomoki Murata, Toru Kondo, Ken-Ichiro Seino. Tumor cell-induced macrophage senescence plays a pivotal role in tumor initiation followed by stable growth in immunocompetent condition. Journal for immunotherapy of cancer. 2023. 11. 11
  • Tomoki Murata, Naoki Hama, Tomoki Kamatani, Akihiro Mori, Ryo Otsuka, Haruka Wada, Ken-Ichiro Seino. Induced pluripotent stem cell-derived hematopoietic stem and progenitor cells induce mixed chimerism and donor-specific allograft tolerance. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2023. 23. 9. 1331-1344
  • Nabeel Kajihara, Yoshino Tanaka, Riko Takeuchi, Takuto Kobayashi, Masafumi Tanji, Tsukasa Ataka, Shiho Nakano, Taisho Yamada, Akinori Takaoka, Yoshinori Hasegawa, et al. Augmented interferon regulatory factor 7 axis in whole tumor cell vaccines prevents tumor recurrence by inducing interferon gamma-secreting B cells. OncoImmunology. 2023. 12. 1
  • Tomoki Murata, Ryo Otsuka, Airi Sasaki, Tomoki Kamatani, Haruka Wada, Hisashi Yamakawa, Yoshinori Hasegawa, Ken-Ichiro Seino. Induction of allograft tolerance by adoptive transfer of donor B cells: an immune regulatory strategy for transplantation using MHC-matched iPS cells. International immunology. 2023
  • Takayoshi Nakamura, Nabeel Kajihara, Naoki Hama, Takuto Kobayashi, Ryo Otsuka, Nanumi Han, Haruka Wada, Yoshinori Hasegawa, Nao Suzuki, Ken-Ichiro Seino. Interleukin-34 cancels anti-tumor immunity by PARP inhibitor. Journal of gynecologic oncology. 2022
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MISC (44)：
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Works (1)：
  • 新規合成レチノイドの免疫抑制と動脈硬化抑制効果に関する研究
Education (1)：
  • - 1997 University of Tsukuba
Professional career (1)：
  • 医学博士
Work history (5)：
  • 2012 - Hokkaido University Institute for Genetic Medicine
  • 2004 - 同上級研究員
  • 2002 - 理化学研究所研究員
  • 1999 - University of Tsukuba Institute of Clinical Medicine
  • 1997 - 日本学術振興会特別研究員
Awards (2)：
  • 1997 - 井上財団奨励賞
  • 1996 - FIMSA Young Investigators Award
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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