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J-GLOBAL ID：200901065167152921   Update date: Jan. 30, 2024

Kataoka Takao

カタオカ タカオ | Kataoka Takao
Affiliation and department：
Former Institution /Organization Tokyo Institute of Technology Center for Biological Resources and Informatics

About Former Institution /Organization Tokyo Institute of Technology Center for Biological Resources and Informatics


Job title： Associate Professor
Research field  (2)： Applied biochemistry ,  Applied molecular and cellular biology
Research theme for competitive and other funds  (17)：
  • 2021 - 2023 細胞傷害顆粒を認識する膜結合型ハイブリッド分子の創製と高純度精製法の開発
  • 2019 - 2022 Molecular mechanisms of bioprobes targeting inflammatory reaction and hypoxic respose
  • 2016 - 2019 Elucidation of molecular mechanisms of bioprobes on signaling pathways of inflammatory responses and hypoxic responses
  • 2015 - 2018 Construction of novel membrane-bound molecular probes for lytic granulces and their functional analysis
  • 2013 - 2016 Molecular mechanisms of signaling pathways regulating inflammatory responses and their elucidation by bioprobes
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Papers (131)：
  • Koichiro Kawaguchi, Tsubasa Ohashi, Narumi Kobayashi, Kotoya Kanemoto, Makoto Nose, Rin Shinozaki, Takao Kataoka, Hiroshi Fujii. Aberrant DNA methylation-mediated NF-κB/fatty acid-binding protein 5 (FABP5) feed-forward loop promotes malignancy of colorectal cancer cells. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2023. 1868. 9. 159362-159362
  • Jinghong Xu, Takuya Hashino, Reiji Tanaka, Koichiro Kawaguchi, Hideki Yoshida, Takao Kataoka. The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis signaling pathway. Scientific reports. 2023. 13. 1. 14041-14041
  • Chiharu Okuda, Yuto Ueda, Makoto Muroi, Emiko Sanada, Hiroyuki Osada, Yoshihito Shiono, Ken-Ichi Kimura, Kenji Takeda, Koichiro Kawaguchi, Takao Kataoka. Allantopyrone A interferes with the degradation of hypoxia-inducible factor 1α protein by reducing proteasome activity in human fibrosarcoma HT-1080 cells. The Journal of antibiotics. 2023. 76. 6. 324-334
  • Takao Kataoka. Biological properties of the BCL-2 family protein BCL-RAMBO, which regulates apoptosis, mitochondrial fragmentation, and mitophagy. Frontiers in Cell and Developmental Biology. 2022. 10. 1065702
  • Takuya Hashino, Hisanori Matsubara, Jinghong Xu, Reiji Tanaka, Eiichi Kusagawa, Yuto Ueda, Hideki Yoshida, Takao Kataoka. PGAM5 interacts with Bcl-rambo and regulates apoptosis and mitophagy. Experimental Cell Research. 2022. 420. 113342
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MISC (22)：
  • Takao Kataoka. Adaptive and innate immune systems. Bioprobes: Biochemical Tools for Investigating Cell Function: Second Edition. 2017. 115-147
  • Liming Bai, Ming Zhao, Yuhua Bai, Asami Toki, Ryo Hasegawa, Junichi Sakai, Toshiaki Hasegawa, Mariko Ando, Tomokazu Mitsui, Hirotsugu Ogura, et al. Bioactive Pregnanes and Cardenolides from Nerium oleander. Bioactive Phytochemicals: Perspectives for Modern Medicine Volume 1. 2012. 1-77
  • Liming Bai, Liming Bai, Liyan Wang, Liyan Wang, Liwei Fu, Liwei Fu, Ming Zhao, Ming Zhao, Shujun Zhang, Shujun Zhang, et al. Oleanane-, ursane-, lupane-, and taraxasterane-type pentacyclic triterpenes isolated from the medicinal plants Nerium Oleander, Ixeris Chinensis, Sonchus Oleraceus And Phytolacca Americana. cytotoxicity studies on human cancer cell lines, and mdr cancer reversal and anti-inflammatory activities. Pentacyclic Triterpenes as Promising Agents in Cancer. 2011. 89-126
  • Ming Zhao, Liwei Fu, Na Li, Wanxia Tang, Minjie Li, Toshiaki Hasegawa, Hirotsugu Ogura, Takao Kataoka, Katutoshi Hirose, Masayoshi Ando. The Ursane-, Oleanane-, Dammarane-, Lupane-, and Taraxasterane-Type Triterpenes Isolated from Nerium oleander and Their Biological Activities. Recent Progress in Medicinal Plants Volume 16 Phytomedicines. 2007. 83-107
  • Tomokazu Mitsui, Takao Kataoka. Modulation of Fas-mediated apoptosis in CTL-mediated cytotoxicity. 2004. 42. 4. 481-484
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Patents (3)：
  • 薬理活性物質
  • Caspase inhibitors for inhibiting blood cell proliferation and for treating autoimmune diseases
  • Pharmacologically active substancce
Lectures and oral presentations  (3)：
  • Screening of compounds that inhibit t he expression of the cell adhesion molecule ICA-1 in vascular endothelial cells
    (Annual Meeting of the Japan Society of Bioscience, Biotechnology, and Agrochemistry, 2023 2023)
  • 1'-Acetoxychavicol acetate selectively reduces the expression of TRAF1 and TRAF2
    (Annual Meeting of the Japan Society of Bioscience, Biotechnology, and Agrochemistry, 2023 2023)
  • PGAM5 interacts with Bcl-rambo and regulates apoptosis and mitophagy
    (The 45th Annual Meeting of the Molecular Biology Society of Japan 2022)
Education (3)：
  • 1989 - 1992 東京大学大学院 農学系研究科 農芸化学専攻博士課程
  • 1987 - 1989 東京大学大学院 農学系研究科 農芸化学専攻修士課程
  • - 1987 The University of Tokyo
Professional career (1)：
  • 博士(農学)
Work history (7)：
  • 2015/04 - 現在 Kyoto Institute of Technology
  • 2007/05 - 2015/03 Kyoto Institute of Technology
  • 2007/04 - 2007/05 Tokyo Institute of Technology Center for Biological Resources and Informatics
  • 2003/04 - 2007/03 Tokyo Institute of Technology Center for Biological Resources and Informatics
  • 2001/08 - 2003/03 東京工業大学 生物実験センター 助教授
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Awards (4)：
  • 2017/09 - 平成29年度「科研費」審査員の表彰
  • 2012/10 - 平成24年度「科研費」審査員の表彰
  • 2003/02 - 東工大挑戦的研究賞
  • 2002/03 - 日本農芸化学会農芸化学奨励賞
Association Membership(s) (4)：
American Society for Biochemistry and Molecular Biology ,  日本分子生物学会 ,  日本生化学会 ,  日本農芸化学会
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