Research field (5)：
Medical biochemistry
, Plastic and reconstructive surgery
, Medical biochemistry
, Developmental biology
, Laboratory animal science
Research theme for competitive and other funds (40)：
2021 - 2024 筋肉内静脈奇形モデルを用いた新規治療法の開発
2021 - 2024 微細血管系としての海綿体の恒常性と異常に関する包括的解析
2017 - 2022 The spectrum of sex depending on ambient temperature
2018 - 2021 Molecular developmental analysis on erectile tissue formation
2015 - 2018 Identification and analysis of new androgen responsive regulatory genes for development and cancer.
2015 - 2017 Analysis on androgen dependent pelvic muscle formation
2010 - 2015 Development of sexual difference in the external-internal genitalia
2010 - 2015 "Molecular mechanisms for establishment of sex differences"
2011 - 2013 The role of androgen signaling for hemato-vascular development
2011 - 2012 The analysis of urinary tract formation; a new approach focused on the developmental role of cloaca during embryogenesis
2008 - 2010 Role of EMT and growth factor cascade in development and cancer.
2005 - 2009 Integrated cancer research using in vivo models
2004 - 2008 Reproduction and maintenance of experimental animals for the study of molecular mechanisms of sex differentiation
2004 - 2008 性分化機構
2004 - 2008 Analysis of the developmental cascade of the mammalian external genitalia
2003 - 2006 Development of mutant mice carrying base-substitutions in target genes.
2004 - 2005 ソノポレーションを用いた付属肢の分子発生学的解析
2004 - 2005 尾部形成と協調した内胚葉末端及び外生殖器発生過程の解析
2002 - 2004 Development of therapeutic ways targeting molecular chaperones and ets transcription factors
2002 - 2003 Molecular mechanisms of appendage formation ; genes involved in the outgrowth, differentiation of appendage formation
2000 - 2001 Development of photometric detection system for tissue aging and study the localization of the aging in tissue
1999 - 2001 Development of knockout mouse of desmoyokin(AHNAK)and analysis of its functio
2000 - 2000 外性器形成過程の発生遺伝学的解析
2000 - 2000 血管構築過程におけるTAB1遺伝子の機能解析
1999 - 2000 Conversion of membrane-anchored HB-EGF into the soluble form.
1999 - 2000 Detection of tissue aging by nanosecond self-fluorescence caused by AGE (Advanced Glycosylation Endproduct)
1996 - 1997 Analysis of expression and function of regulatory molecules in the whole embryos by new developmetnal engineering system
1996 - 1996 グ-スコイド遺伝子変異マウスを用いた顔面-頭部形成機構の解析
1989 - 1991 リンフォカインと受容体の発現制御
1989 - 1989 リンフォカインと受容体の遺伝子発現とリンパ球増殖の制御機構の解析
1988 - 1988 リンフォカインと受容体の遺伝子発現とリンパ球増殖の制御機構の解析
1987 - 1987 リンフォカインと受容体の遺伝子発現とリンパ球増殖の制御機構の解析
1986 - 1987 Molecular regulatory mechanism of gene expression in immune system.
高等動物の器官形成過程の分子的解析
Molecular developmental analysis on organogenesis
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Papers (98)：
Daiki Hashimoto, Kota Fujimoto, Sang Woon Kim, Yong Seung Lee, Masanori Nakata, Kentaro Suzuki, Yoshitaka Wada, Shinichi Asamura, Gen Yamada. Emerging structural and pathological analyses on the erectile organ, corpus cavernous containing sinusoids. Reproductive medicine and biology. 2023. 22. 1. e12539
Kosei Tanaka, Daisuke Matsumaru, Kentaro Suzuki, Gen Yamada, Shinichi Miyagawa. The role of p63 in embryonic external genitalia outgrowth in mice. Development, growth & differentiation. 2023. 65. 2. 132-140
Mellissa C Alcantara, Kentaro Suzuki, Alvin R Acebedo, Daiki Kajioka, Satoshi Hirohata, Tsuneyasu Kaisho, Yu Hatano, Kazuo Yamagata, Satoru Takahashi, Gen Yamada. Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice. iScience. 2022. 25. 12. 105609-105609
Alvin R Acebedo, Mellissa C Alcantara, Tsuyoshi Nakanishi, Takehiko Ogawa, Gen Yamada, Kentaro Suzuki. Exposure to the organophosphate pesticide fenitrothion directly induced defects in mouse embryonic external genitalia. Toxicological sciences : an official journal of the Society of Toxicology. 2022
Mizuki Kajimoto, Kentaro Suzuki, Yuko Ueda, Kota Fujimoto, Toru Takeo, Naomi Nakagata, Taiju Hyuga, Kyoichi Isono, Gen Yamada. Androgen/Wnt/β-catenin signal axis augments cell proliferation of the mouse erectile tissue, corpus cavernosum. Congenital anomalies. 2022. 62. 3. 123-133
Aki Murashima, Gen Yamada. The roles of androgen and growth factor signaling in Wolffian duct development. MECHANISMS OF DEVELOPMENT. 2017. 145. S150-S150
Yukiko Ogino, Shinichi Miyagawa, Hironori Katoh, Gail S. Prins, Taisen Iguchi, Gen Yamada. Essential functions of androgen signaling emerged through the developmental analysis of vertebrate sex characteristics. EVOLUTION & DEVELOPMENT. 2011. 13. 3. 315-325
CARD; a core center for transgenic/gene knockout mouse research. Application of gene engineered mice for developmental biology and medical studies.
(The 2nd China-Japan Cooperative Life Science Symposium in Kunming 2005)
External genitalia formation; a model system to study organogenesis
(Society for Developmental Biology 64th Annual Meeting 2005)
