Rchr

J-GLOBAL ID：200901065436078288 Update date: Dec. 06, 2023

Ito Sachiko

イトウサチコ | Ito Sachiko

Affiliation and department：
Job title： Lecturer

Research field (1)： Immunology

Research keywords (2)：免疫学 , 腫瘍免疫

Research theme for competitive and other funds (6)：

2019 - 2021 がん免疫療法抵抗性を解除する新規治療法の臨床展開に向けた開発研究
2016 - 2019 先端的がん免疫モニタリング法開発体制に関する研究
2015 - 2018 自然免疫応答および炎症関連性癌発症におけるGADD34の機能解析
2012 - 2015 細胞増殖・移動と栄養制御ストレスに対する細胞防御におけるGADD34の機能解析
2010 - 2012 老化と栄養制御、創傷治癒におけるGADD34の遺伝子欠損マウスを用いた機能解析

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Papers (45)：

Muramatsu T, Noguchi T, Sugiyama D, Kanada Y, Fujimaki K, Ito S, Gotoh M, Nishikawa H. Newly emerged immunogenic neoantigens in established tumors enable hosts to regain immunosurveillance in a T cell-dependent manner. Int Immunol. 2020
Tokunaga A, Sugiyama D, Maeda Y, Warner AB, Panageas KS, Ito S, Togashi Y, Sakai C, Wolchok JD, Nishikawa H. Selective inhibition of low-affinity memory CD8+ T cells by corticosteroids. J Exp Med. 2019. 216. 12. 2701-2713
Du Q, Tsuboi N, Shi Y, Ito S, Sugiyama Y, Furuhashi K, Endo N, Kim H, Katsuno T, Akiyama S, et al. Transfusion of CD206+ M2 Macrophages Ameliorates Antibody-Mediated Glomerulonephritis in Mice. Am J Pathol. 2016. 186. 12. 3176-3188
Liu L, Ito S, Nishio N, Sun Y, Tanaka Y, Isobe K. GADD34 Promotes Tumor Growth by Inducing Myeloid-derived Suppressor Cells. Anticancer Res. 2016. 36. 9. 4623-8
Tanaka Y, Ito S, Isobe K. Vancomycin-sensitive bacteria trigger development of colitis-associated colon cancer by attracting neutrophils. Sci Rep. 2016. 6

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MISC (43)：

Du Q, Tsuboi N, Shi Y, Ito S, Sugiyama Y, Furuhashi K, Endo N, Kim H, Katsuno T, Akiyama S, et al. Transfusion of CD206+ M2 Macrophages Ameliorates Antibody-Mediated Glomerulonephritis in Mice. Am J Pathol. 2016. 186. 12. 3176-3188
Liu L, Ito S, Nishio N, Sun Y, Tanaka Y, Isobe K. GADD34 Promotes Tumor Growth by Inducing Myeloid-derived Suppressor Cells. Anticancer Res. 2016. 36. 9. 4623-8
Tanaka Y, Ito S, Isobe K. Vancomycin-sensitive bacteria trigger development of colitis-associated colon cancer by attracting neutrophils. Sci Rep. 2016. 6
Ito S, Tanaka Y, Oshino R, Okado S, Hori M, Isobe KI. GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation. Cell Death Dis. 2016. 7
Okabe M, Ito S, Nishio N, Tanaka Y, Isobe K. Thymic Epithelial Cells Induced from Pluripotent Stem Cells by a Three-Dimensional Spheroid Culture System Regenerates Functional T Cells in Nude Mice. Cell Reprogram. 2015. 17. 5. 368-75

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Books (1)：

Surgical Trauma & Immunological Responses
2011

Lectures and oral presentations (2)：

Loss of GAD34 induces early immune aging: impact on the proliferation of neutrophil-linage cells.
(2012)
The expression of GADD34 is induced by various TLR ligands and affects the cytokine productions via TLR signaling
(2012)

Professional career (1)：

医学 (名古屋大学)

Work history (4)：

2015/06/01 - 現在 Nagoya University Graduate School of Medicine Program in Integrated Medicine Microbiology and Immunology Lecturer
2009/04/01 - 2015/05/31 Nagoya University Program in Integrated Molecular Medicine Assistant Professor
2009/01/01 - 2009/03/31 Nagoya University Graduate School of Medicine COE designated assistant professor
2007/05/01 - 2008/12/31 Nagoya University Graduate School of Medicine Center for Research of Laboratory Animals and Medical Research Engineering Assistant Professor

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