Rchr
J-GLOBAL ID：200901065830447337
Update date: Jan. 30, 2024
Fujiwara Hideaki
フジワラ ヒデアキ | Fujiwara Hideaki
Affiliation and department：
Job title：
Invited Professor
Homepage URL (1)：
http://sahswww.med.osaka-u.ac.jp/~phys-chem/index.html
Research field (4)：
Radiology
, Pharmaceuticals - chemistry and drug development
, Biomaterials
, Biomedical engineering
Research keywords (6)：
造影剤
, 超偏極希ガスイメージング
, 磁気共鳴イメージング
, Hyperpolarized Noble Gas MRI
, Magnetic Resonance Imaging
, Magnetic Resonance
Research theme for competitive and other funds (18)：
- 2012 - 2016 Development of preclinical system based on pulmonary functional imaging by hyperpolarized Xe MRI
- 2007 - 臨床での展開を目指したMR基礎技術の開発
- 2007 - Basic Development of MRI for Clinical Purpose
- 2002 - 2004 簡易連続型超偏極希ガス生成装置の試作と水素や炭素核の高感度MRI実験への応用
- 2002 - 2004 Applied Clinical Study on Hyperpolarized Noble Gas MRI/MRS using Pathologic Model Animal
- 2001 - 2002 超偏極希ガス簡易供給装置の開発と高感度磁気共鳴による脳機能計測の研究
- 2001 - 2002 液晶NMR法におけるキラル液晶系の利用と天然分子の絶対構造決定の開発
- 2000 - 2000 磁気的な直接結合定数を利用した構造解析法の開発と微量天然物への応用展開研究
- 1999 - 2000 Non-linear Analysis of Medical and Pharmaceutical Data using Neural Network and Generalized Additive Model
- 1998 - 2000 Skill of intravenous ultrasonic contrast agent for evaluation of microcirculation of human organs and its assessment for clinical use.
- 1999 - 超偏極希ガスイメージングの基礎開発と応用
- 1999 - Studies of Basic and Applied Aspects of Hyperpolarized Noble Gas MRI
- 1996 - 1997 Improvement of Artificial Neural Networks and Its Applications to QSARs.
- 1995 - 1996 A Novel Agent for Contrast Echocardiography and its Evaluation in a Distinctive Clinical Application.
- 1994 - 1995 金属イオンの膜透過性を支配する天然超分子のNMRによる研究
- 1995 - MRI造影剤の開発
- 1995 - Development of Contrast Agents for MRI and Ultrasonic Diagnostics
- 1994 - 1994 金属イオンの膜透過性を支配する天然超分子のNMRによる研究
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Papers (63)：
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Atsuomi Kimura, Seiya Utsumi, Akihiro Shimokawa, Renya Nishimori, Rie Hosoi, Neil J. Stewart, Hirohiko Imai, Hideaki Fujiwara. Targeted Imaging of Lung Cancer with Hyperpolarized 129Xe MRI Using Surface-Modified Iron Oxide Nanoparticles as Molecular Contrast Agents. Cancers. 2022. 14. 24. 6070-6070
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Tetsuya Wakayama, Tsuyoshi Ueyama, Fumito Imai, Atsuomi Kimura, Hideaki Fujiwara. Quantitative assessment of regional lung ventilation in emphysematous mice using hyperpolarized 129Xe MRI with a continuous flow hyperpolarizing system. Magnetic Resonance Imaging, 92, 88-95 (2022). 2022. 92. 88-95
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Atsuomi Kimura, Seiya Utsumi, Akihiro Shimokawa, Renya Nishimori, Neil J. Stewart, Yoshihiro Kamada, Hirohiko Imai, Hideaki Fujiwara. Inflammation during Lung Cancer Progression and Ethyl Pyruvate Treatment Observed by Pulmonary Functional Hyperpolarized 129Xe MRI in Mice. Contrast Media & Molecular Imaging. 2021. 2021. 1-10
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Hideaki Fujiwara, Hirohiko Imai, Yuko Adachi, Atsuomi Kimura. Analysis of NMR Adsorption Isotherms of Zeolite ZSM-5: Adsorption Profiles Derived from the Pressure and Temperature Dependences of 129Xe NMR Chemical Shift and Signal Intensity. Anal. Sci., 2021;37:1803-1810. 2021. 37. 1803-1810
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Mizushima R, Inoue K, Fujiwara H, Iwane AH, Watanabe TM, Kimura A. Multiplexed 129Xe HyperCEST MRI Detection of Genetically Reconstituted Bacterial Protein Nanoparticles in Human Cancer Cells. Contrast Media Mol Imaging. 2020. 2020. 2020. 5425934
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MISC (107)：
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藤原英明, 今井宏彦, 木村敦臣. 頑強で持続可能な超偏極キセノンガス生成供給装置の開発と応用. 第58回NMR討論会. 2019. L3-1
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藤原英明, 小林美一, 今井宏彦, 木村敦臣. 超偏極キセノンガス生成供給装置普及版の開発と高分子への応用. 第79回分析化学討論会. 2019. F1009R
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藤原英明, 今井宏彦, 木村敦臣. 超偏極キセノンガス生成供給装置普及版の作成と応用. 第57回NMR討論会. 2018. P89
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木村敦臣, 下川晃弘, 程野祥太, 上田ひかり, Neil J. Stewar, 山根麻実, 西森廉弥, 今井宏彦, 藤原英明. 超偏極キセノンMRIによる肺線維症の前臨床評価. 第10回呼吸機能イメージング研究会学術集会. 2018. P4-1
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Atsuomi Kimura, Hirohiko Imai, Hideaki Fujiwara. An Organic Gas instead of Inorganic Gases for the Enhancement of 129Xe Magnetic Resonance Signals through Optical Pumping. 2017
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Patents (3)：
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超偏極希ガス生成供給装置
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偏極キセノンガスの濃縮方法及び偏極キセノンガスの製造供給装置
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偏極希ガスの製造方法
Books (14)：
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Hyperpolarized and inert gas MRI : from technology to application in research and medicine, Editors M. S. Albert; F. T. Hane
Academic Press 2017 ISBN:9780128036754
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Hyperpolarized and inert gas MRI : from technology to application in research and medicine, Editors M. S. Albert; F. T. Hane
Academic Press 2017 ISBN:9780128036754
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Hyperpolarized Xenon-129 Magnetic Resonance: Concepts, Production, Techniques and Applications, Editors: Thomas Meersmann; Eike Brunner
Royal Society of Chemistry 2015 ISBN:9781849738897
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非侵襲・可視化技術ハンドブック-ナノ・バイオ・医療から情報システムまで-
(株)エヌ・ティー・エス 2007
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エクセルナース 検査編
メディカルレビュー社 2004
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Education (4)：
- - 1974 Tohoku University
- - 1974 Tohoku University Graduate School, Faculty of Science
- - 1969 Nagoya Institute of Technology Faculty of Engineering
- - 1969 Nagoya Institute of Technology Faculty of Engineering
Professional career (2)：
Work history (3)：
- 1992 - 1995 Osaka University School of Pharmaceutical Sciences
- 1992 - 1995 Professor, Faculty of Pharmaceutical Sciences,
- Osaka University
Committee career (7)：
Association Membership(s) (7)：
International Society of Magnetic Resonance
, 日本核磁気共鳴学会
, 日本磁気共鳴医学会
, International Society for Magnetic Resonance in Medicine
, 日本分析化学会
, 日本化学会
, 日本薬学会
