Rchr

J-GLOBAL ID：200901065831663220 Update date: Apr. 09, 2024

Morimoto Yoshiki

モリモトヨシキ | Morimoto Yoshiki

Affiliation and department：
Job title： Professor
Homepage URL (2)： http://www.sci.osaka-cu.ac.jp/chem/org2/index.html , https://research-soran17.osaka-cu.ac.jp/html/100000631_en.html

Research field (8)： Synthetic organic chemistry , Molecular biochemistry , Other , Molecular biochemistry , Other , Structural/physical organic chemistry , Synthetic organic chemistry , Bioorganic chemistry

Research keywords (10)： Biological Activity , Biomimetic Synthesis , Biosynthesis , Structure-Activity Relationships , Structure Determination , Natural Product Synthesis , Total Synthesis , Asymmetric Synthesis , Chemical Biology , Cascade Reaction

Research theme for competitive and other funds (35)：

2019 - 2022 含窒素スピロ環を一挙構築する不斉環化異性化反応の開発:アルカロイド合成の新戦略
2019 - 2021 アレルギー様食中毒防止のためのヒスタミン解毒効果のある嗜好的調理法の確立
2018 - 2020 Efficient Synthesis of Triterpenoid Middle Molecules by Integrating Chemical and Enzymatic Syntheses
2016 - 2020 Chemical Biology of Halogenated Antifouling Compounds
2018 - 2019 Exploration of Natural Products with Enantiodivergency and Clarification of Their Production Mechanism

2014 - 2018 Development of in vitro absorption evaluation method for practical application of included functional food and practical study on new complex

2013 - 2014 Creation of Molecular Technology towards Development of Pharmaceuticals for Complex Molecules

2008 - 2012 Studies on Molecular Science of Biologically Active Natural Products Based on Chemical Synthesis

2010 - 2012 Dynamic Molecular Science Innovation

2010 - 2011 Studies on the Biomimetic Key Reaction of Triterpene Polyethers

2005 - 2008 Molecular Scientific Research on Cytotoxic Oxasqualenoids Based on Chemical Synthesis

2007 - 2008 Studies on Chemical Synthesis of Structurally Novel Cytotoxic Alkaloids Haouamines toward Pharmaceuticals

2006 - 2007 Synthetic Studies on Cytotoxic Biofunctional Alkaloid Haouamine with a New Skeleton

2005 - 2006 Synthesis of Cytotoxic Biofunctional Oxasqualenoids Using a Cascade Cyclization Reaction

2005 - 2006 Structures and Dynamics of Water Clusters Stabilized by Molecular Porous Coordination Space

2004 - 2005 Synthetic Studies on Marine Cytotoxic Halogen-Containing Oxasqualenoids

2003 - 2004 Structural Studies on Cytotoxic Oxasqualenoids by Chemical Synthesis

2001 - 2003 Chemical Synthetic Approach towards Clarifying Mechanism of Action for Cytotoxicity of Squalene-Derived Polyethers

2001 - 2002 Development of Efficient Synthetic Strategy for Marine Biologically Active Macrocyclic Alkaloids

2001 - 2002 Synthetic Studies on Polyethers Isolated from Plants and Clarification of the Functions and Construction of the Artificial Molecules

1999 - 2001 Synthetic Studies on Antitumor Alkaloids Manzamines by a Biogenetic-like Route

2000 - 2001 Development of Oxidation Reactions Using Rhenium at High Oxidation State and the Application to Organic Synthesis

1998 - 2001 Organic Synthetic Approach towards Clarifying Mechanism of Action for Cytotoxicity of Squalene-Derived Polyethers

2000 - 2001 Chemical Synthetic Approach towards Clarifying Mechanism of Action for Cytotoxicity of Squalene-Derived Polyethers

1997 - 1999 Studies on Asymmetric Synthesis of Biologically Active Alkaloids Tuberostemonines with Specific Skeletons

1999 - Development of Oxidation Reactions Using Rhenium at High Oxidation State and the Application to Organic Synthesis

1998 - 1999 Synthetic Chemical Approach towards Clarifying Mechanism of Action for Cytotoxicity of Squalene-Derived Polyethers

1997 - 1998 Synthesis of Biologically Active Polyethers and Clarification of the Functions

1997 - 1998 Synthetic Studies on Antitumor Alkaloids Manzamines by a Biogenetic-like Route

1996 - 1997 Studies on Asymmetric Synthesis of Biologically Active Alkaloids Tuberostemonines with Specific Skeletons

1996 - 1997 Synthetic Studies on Polyethers Isolated from Plants and Clarification of the Functions and Construction of the Artificial Molecules

1995 - 1996 Studies on Asymmetric Synthesis of Biologically Active Alkaloids Tuberostemonines with Specific Skeletons

1994 - 1995 Studies on Asymmetric Synthesis of Biologically Active Alkaloids Tuberostemonines with Specific Skeletons

1991 - 1992 Development of an Asymmetric Aziridination Reaction and the Application to Natural Product Synthesis

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Papers (117)：

Shinnosuke Ishigami, Ryosuke Fukada, Genki Nagasaka, Tomoki Tsuruta, Keisuke Nishikawa, Yu Sasaki, Kazumi Nimura, Iori Oshima, Yukimasa Yamagishi, Yoshiki Morimoto, et al. Halogenated Cyclic Monoterpenoids with Anti-biofouling Activity from the Okinawan Red Marine Alga Portieria hornemannii. Chemistry & Biodiversity. 2024. 21. e202400436
Keisuke Nishikawa, Yosuke Ono, Sumito Mori, Koichi Takayama, Makoto Ihara, Kazuhiko Matsuda, Yoshiki Morimoto. Divergent Nine-Step Syntheses of Perhydrohistrionicotoxin Analogs and Their Inhibition Activity Toward Chicken ⍺4β2-Neuronal Nicotinic Acetylcholine Receptors. The Journal of Organic Chemistry. 2024. 89. 6. 4128-4133
Momochika Kumagai, Akana Matsuda, Nozomi Shiiba, Tomoki Tsuruta, Hikaru Endo, Keisuke Nishikawa, Yoshiki Morimoto. Structure-Activity Relationship of anti-Inflammatory Meroterpenoids Isolated from Dictyopteris polypodioides in RAW264 Cells. Bioscience, Biotechnology & Biochemistry. 2024. 88
Keisuke Nishikawa, Tomonori Teranishi, Tomoki Tsuruta, Toshiki Niwa, Kengo Morita, Subaru Hashimoto, Akihiro Hoshino, Momochika Kumagai, Yoshiki Morimoto. Establishment of “Ring-Size-Divergent” Synthetic Strategy: Divergent Synthesis, Stereochemical Assignments, and Biological Activity Studies of Nerolidol-Type Sesquiterpenoids and Feroniellins. The Journal of Organic Chemistry. 2023
Keisuke Nishikawa, Naoto Taki, Kento Nishikibe, Momochika Kumagai, Yoshiki Morimoto. Total Synthesis, Revised Structure, and Cytotoxic Activities of Iubol. Chemistry Letters. 2022. 51. 10. 1000-1003

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MISC (7)：

Keisuke Nishikawa, Yoshiki Morimoto. Asymmetric Total Synthesis of Toxicodenanes by the Samarium Iodide-Induced Barbier-Type Cyclization Reaction as a Key Step: Seeking of Seed Compounds for the Small Molecule Drug Discovery of Diabetic Nephropathy. Fine Chemicals. 2023. 52. 1. 36-44
Yoshiki Morimoto. What Is University?. Rutsubo. 2010. 58. 46-48
Yoshiki Morimoto. Studies on the Molecular Science of Cytotoxic Oxasqualenoids Based on Chemical Synthesis. Research Report on Grant-in-Aid for Scientific Research (C) in 2005-2008. 2008. 1-89
Yoshiki Morimoto. Chemical Synthetic Approach towards Clarifying Mechanism of Action for Cytotoxicity of Squalene-Derived Polyethers. Research Report on Grant-in-Aid for Scientific Research (C) (2) in 2001-2003. 2003. 1-66
Yoshiki Morimoto. Studies on Total Synthesis of Squalene-Derived Cytotoxic Triterpene Polyethers. 2003. 15. 2-8

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Books (8)：

Basic Chemistry Experiments, Third Modified Edition
Fukuro Shuppan 2017 ISBN:9784861866869
Basic Chemistry Experiments, Second Modified Edition
Fukuro Shuppan 2014 ISBN:9784861865855
Reactions Culminated in Natural Product Synthesis-Know-how and Points in Experiments
Kagakudojin Company, Limited 2011 ISBN:9784759814798
Basic Chemistry Experiments, Modified Edition
Fukuro Shuppan 2010 ISBN:9784861864162
High School Students//Chemistry Declaration Part 3
u-time Publishing Company, Limited 2010 ISBN:9784860102814

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Lectures and oral presentations (113)：

Synthetic Studies on the Seco-Dolastane-Type Diterpene Isolinearol
(The 104th CSJ Annual Meeting (2024) 2024)
Synthetic Studies on Lolitrem B
(The 104th CSJ Annual Meeting (2024) 2024)
ペルヒドロヒストリオニコトキシン類のニコチン性アセチルコリン受容体に対する阻害活性の構造活性相関
(日本農薬学会第49回大会 2024)
World of Natural Organic Compounds Produced by Organisms
(Expert Course, Academic Extension Center, Osaka Metropolitan University 2023)
Studies on Total Synthesis of the Dolastane-Type Diterpene Possessing Inhibition Activity against Byssal Threads of the Mussel
(The 15th International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-15) 2023)

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Education (4)：

1987 - 1991 Hokkaido University Graduate School of Science Division of Chemistry
1987 - 1991 Hokkaido University Graduate School, Division of Natural Science Division of Chemistry
1985 - 1987 Hokkaido University Graduate School of Science Division of Chemistry
1981 - 1985 Hokkaido University Faculty of Science Department of Chemistry

Professional career (2)：

Doctor of Science (Hokkaido University)
Master of Science (Hokkaido University)

Work history (11)：

2022/04 - 現在 Osaka Metropolitan University Graduate School of Science Department of Chemistry Professor
2007/04/01 - 現在 Osaka City University Graduate School of Science Professor
1992/04/01 - 現在 Osaka City University Graduate School of Science Molecular Materials Science Course Professor
2022/12 - 2022/12 Kyushu University Adjunct Instructor
2017/08 - 2017/08 Hokkaido University Graduate School of Environmental Science Adjunct Instructor

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Committee career (28)：

2012/12 - 2103/03 日本化学会第93春季年会プログラム編成委員、学生講演賞審査委員
2023/04 - 2024/03 The 52th Congress of Heterocyclic Chemistry manager
2023 - 2024 第15回国際有機化学京都会議(IKCOC-15) 組織委員
2019/12 - 2023/11 The Society of Synthetic Organic Chemistry, Japan representative
2022/04 - 2023/03 The 51st Congress of Heterocyclic Chemistry manager

2022/12 - 2022/12 Institute for Materials Chemistry and Engineering, Kyushu University Research Mentor

2019/12 - 2022/10 Japan Society for the Promotion of Science Reviewers of the Scientific Research Grant Committee

2021/04 - 2022/03 第50回複素環化学討論会世話人

2021/03 - 2021/03 日本化学会第101春季年会学生講演賞審査員

2018/10 - 2019/09 第27回国際複素環化学会議(27th ISHC Congress) 組織委員

2019/03 - 2019/03 日本化学会第99春季年会優秀講演賞・学生講演賞審査員

2017/08 - 2018/07 独立行政法人日本学術振興会特別研究員等審査会専門委員、卓越研究員候補者選考委員会書面審査員及び国際事業委員会書面審査員・書面評価員

2018/03 - 2018/03 日本化学会第98春季年会学生講演賞審査員

2017 - 2018 第14回国際有機化学京都会議(IKCOC-14) 組織委員

2017/03 - 2017/03 日本化学会第97春季年会学生講演賞審査員

2017 - 2017 第47回複素環化学討論会世話人

2016 - 2017 第20回大阪市立大学国際会議(ICUIC-2016) 組織委員

2016/03 - 2016/03 日本化学会第96春季年会優秀講演賞・学生講演賞審査員

2014 - 2016 第13回国際有機化学京都会議(IKCOC-13) 組織委員

2014 - 2014 第44回複素環化学討論会世話人、学生講演賞審査員

2012/03 - 2012/03 日本化学会第92春季年会優秀講演賞・学生講演賞審査委員

2011 - 2011 大阪市立大学重点研究シンポジウム「天然物分子科学研究の最前線」組織委員長

2010 - 2011 The 15th Osaka City University International Conference on Spin Chemistry and Dynamic Molecular Science & Research Meeting of Dynamic Molecular Devices 組織委員長、学生ポスター賞審査委員

2009/12 - 2010/03 日本化学会第90春季年会プログラム編成委員、学生講演賞審査委員

2007 - 2008 日本化学会近畿支部代議員

2003 - 2006 有機合成化学協会評議員

2000 - 2003 有機合成化学協会関西支部幹事

1997 - 1999 日本化学会「化学と工業」誌トピックス委員会委員

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Awards (6)：

2022/09 - Public University Corporation Osaka Metropolitan University Long Service Award (30 years) Long Service Award (30 years)
2018/04 - Nagase Science Technology Foundation Nagase Research Promotion Award Exploration of Natural Products with Enantiodivergency and Clarification of Their Production Mechanism
2018/03 - 公立大学法人大阪市立大学永年勤続表彰永年勤続表彰
2003/11 - Kansai Branch, The Society of Synthetic Organic Chemistry, Japan Kansai Branch Award in Synthetic Organic Chemistry, Japan Development of Stereoselective Polytetrahydrofuran Construction Method and the Application to Natural Product Synthesis
2001/03 - The Chemical Society of Japan Lectureship for Young Chemists of 79th National Meeting of the Chemical Society of Japan Total Synthesis of Highly Symmetric Squalene-derived Cytotoxic Polyethers Teurilene and Glabrescol

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Association Membership(s) (2)：

The Society of Synthetic Organic Chemistry, Japan , The Chemical Society of Japan

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