J-GLOBAL ID:200901069013655373   Update date: Nov. 28, 2019

KUBO Masato

クボ マサト | KUBO Masato
Affiliation and department:
Job title: Professor
Research field  (1): Immunology
Research keywords  (1): Immunology, Allergology
Research theme for competitive and other funds  (2):
  • Mechanism of Cytokine Synthesis in T Lymphocyte
  • Calcium-Dependent Signal Transcluction Mechanisms in T Lymphocyte
Papers (136):
  • Kubo M. Mast cells and basophils in allergic inflammation. CURRENT OPINION IN IMMUNOLOGY. 2018. 54. 74-79
  • Tashiro Y, Murakami A, Hara Y, Shimizu T, Kubo M, Goitsuka R, Kishimoto H, Azuma T. High-affinity IgM+ memory B cells are defective in differentiation into IgM antibody-secreting cells by re-stimulation with a T cell-dependent antigen. Scientific Reports. 2018. 8. 1. 14559
  • Hitomi K, Tahara-Hanaoka S, Miki H, Iwata K, Shibayama S, Kubo M, Shibuya A. Allergin-1 on mast cells suppresses house dust mite-induced airway hyperresponsiveness in mice. INTERNATIONAL IMMUNOLOGY. 2018. 30. 9. 429-434
  • Hosoi, A., Takeda, K., Nagaoka, K., Iino, T., Matsushita, H., Ueha, S., Aoki, S., Matsushima, K., Kubo, M., Morikawa, T., Kitaura, K., Suzuki, R., Kakimi, K. Increased diversity with reduced “diversity evenness” of tumor infiltrating T-cells for the successful cancer immunotherapy. Scientific Reports. 2018. 8. 1. 1058
  • Moriyasu T, Nakamura R, Deloer S, Senba M, Kubo M, Inoue M, Culleton R, Hamano S. Schistosoma mansoni infection suppresses the growth of Plasmodium yoelii parasites in the liver and reduces gametocyte infectivity to mosquitoes. PLoS Neglected Tropical Diseases. 2018. 12. 1. e0006197
MISC (53):
Books (2):
  • Involvement of Jak-STAT cascade in T cell subset-specific-expression of IL-4 gene.
    Monduzzi Editore 1 1998
  • TCR-mediated signal transduction pathway that control helper T cell differentiation : Requirement for activation of Lck tyrosine kinase and Ras/MAPK pathway in Th2 cell differentiation.
    Monduzzi Editore 1 1998
Lectures and oral presentations  (186):
  • Role of suppressor of cytokine signaling (SOCS) in helper T cell differentiation
  • A conserved non-cording sequence (CNS)-2 in the IL-4 locus is a specific enhancer for IL-4 production in memory T cells, NKT cells and Mast cells
    (Immunology 2003 The American Association of Immunologists and Clinical Immunology Society Joint Annual Meeting 2003)
  • 「Why Do Allergic Persist」、The role of SOCS3 for persistence of allergic inflammation.
    (The American Academy of Allergy Asthma & Immunology 2004 Annual Meeting 2004)
  • 「アレルギー/アトピー性疾患」 細胞内シグナル伝達とアレルギー疾患
    (第126回日本医学会シンポジウム 2004)
  • 「Th2細胞とアレルギー反応」
    (日本動物細胞工学会シンポジウム 2004)
Works (1):
  • Development of anti-allergic drug
    1995 - 2002
Education (1):
  • - 1991 The University of Tokyo Graduate School, Division of Medicine Immunology
Professional career (1):
  • Ph.D (The University of Tokyo)
Committee career (3):
  • 2017/10/01 - 2019/09/30 International Cytokine & Interferon Society Meetings Committee Counsel
  • 2010/12/01 - 2020/11/30 Frontiers Immunology Editor
  • 2006/04/01 - 2010/03/31 International Immunology Associate Editor
Association Membership(s) (3):
Frontiers Immunology ,  International Cytokine & Interferon Society ,  International Immunology
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