Kohzuki Masahiro | Researcher Information

2021 - 2026 Development of proper exercise intensity for endothelial dysfunction.
2022 - 2025 Study of long-term clinical economic impact of adherence: AI and big data predictive model development
2021 - 2024 Role of renal sympathetic nerve and myokine in inhibitory effects of exercise on the progression of polycystic kidney disease
2020 - 2023 Effects of exercise training on mitochondrial function in organs
2020 - 2023 ビッグデータを用いた全ゲノム情報解析による腎臓リハビリテーションの個別化構築

2019 - 2023 教育成果評価のための新しいQOL尺度の開発

2017 - 2020 Effects of exercise training on organ damage and fibrosis

2017 - 2020 Renal rehabilitation: clarify the mechanisms of renal protection and extension of rehebilitation coverage

2015 - 2020 Development of a personalized respiratory rehabilitation instruction method for patients with respiratory diseases and verification of its effectiveness

2016 - 2019 Elucidation of a mechanism of epileptic seizure induction by using multimodal autonomic monitoring

2016 - 2019 Effects of exercise and drug therapies in heart failure models

2015 - 2019 Therapeutic and preventive effects and mechanisms of exercise training on renal disorder of salt-sensitive hypertension

2016 - 2018 Establishment of the renal rehabilitation program to prevent the decline of renal function

2015 - 2018 Renal rehabilitation program oriented to oxidative stress control

2015 - 2018 New device for real-time temperature measurement during 3T-MR under the temperature rise associated with SAR: aiming for the development of rapid-sequence cardiac MR for rehabilitation patients

2015 - 2018 Effects of chronic exercise in polycystic kidney rats

2015 - 2018 Development of Scale to Special Needs Education Assessment Tool(SNEAT)

2015 - 2018 Effects of a renal rehabilitation exercise program in elderly patients with chronic renal falure

2014 - 2017 リハビリテーション運動療法における臓器連関の機序解明

2014 - 2017 Renal Rehabilitation: Promotion of research for the guidelines on the practical application of new device for patients with CKD

2014 - 2017 Mechanism of effectiveness of exercise training in progressive organ diseases

2014 - 2016 To provide a renal rehabilitation program having an excellent treating or preventing effect on the physical function.

2013 - 2016 Rehabilitation and exercise stress test of physical function and QOL improvement of paroxysmal atrial fibrillation patients.

2013 - 2016 Development of health promotion theory that applies behavioral economics and research of verification in action of taking medicine

2013 - 2016 The establishment of new effective strategy for renal rehabilitation in a progressive renal disease.

2013 - 2016 Elucidation of the rehabilitation effects on nitric oxide and sympathetic nervous system

2012 - 2016 Development of pulmonary rehabilitation improving prognosis by focusing on cough and swallowing functions.

2012 - 2015 Fundamental study of magnetic resonance examination for cardiac rehabilitation patient: Development of a real-time measurement device for temperature in the gantry during magnetic resonance imaging

2012 - 2015 Effects of comprehensive rehabilitation in patients with non-alcoholic fatty liver disease (NAFLD)

2012 - 2015 Effects of a Renal Rehabilitation Exercise Program in Patients with CKD

2012 - 2015 The examination of the stress improvement caused by electrical stimulation on heart failure or respiratory failure patients

2012 - 2015 Mechanism behind cardioprotective effect after chronic exercise in heart failure rats.

2010 - 2015 Pysical Inactivities and systemic inflammation. Investigation of anti-inflammatory effects of exercise in patiens with chronic respiratory disease

2012 - 2014 Effects of electrical stimulation of the abdomen in inactive elderly patients with chronic indwelling urinary catheters

2011 - 2014 Mechanism of pleiotropic effects of exercise training in inter-organ communication

2011 - 2014 Renal rehabilitation: clarification of mechanism of effectiveness and clinical application

2011 - 2012 Study on theory establishment of National Health Insurance Listing in which willingness to pay is adjusted to budget

2011 - 2012 Effect of voluntary exercise training on physical functions and QOL in hematopoietic stem cell transplantation patients

2010 - 2012 The development of the new ADL evaluation list for COPD patients at home and effect measurement of pulmonary rehabilitation using it

2010 - 2011 Effects of comprehensive rehabilitation in peripheral arterial disease

2009 - 2011 The mechanism elucidation of renal rehabilitation in a progressive renal disease

2009 - 2011 Expression of vasoactive substances in heart failure model of exercise therapy.

2008 - 2011 Development of continuous self-management system for patients with cardiovascular disease in ubiquitous society

2008 - 2010 Mechanism of beneficial effects of combination therapy with exercise training and antioxidant

2008 - 2010 Basic research for renal rehabilitation : Clarification of mechanism of cardiovascular disease prevention

2008 - 2009 小児の脂肪性肝疾患(NAFLD)への入院型包括的リハビリテーションの有効性の確立

2007 - 2008 MRI examination during dynamic muscular exercise

2007 - 2008 Elucidation of the mechanism that combination therapy with long-term exercise, G-CSF and nutrition therapy effectively inhibits the aggravation of progressive renal disease

2006 - 2007 Mechanism of the beneficial effects of exercise training and lipid lowering drug therapy

2006 - 2007 Basal Verification of the Renal Rehabilitation to Establish Evidence

2005 - 2007 Fundamental verification of pulmonary rehabilitation technique and its establishment of the significance

2005 - 2006 呼気気道濃縮液中の酸化物質定量による内部障害者の運動強度妥当性評価の試み

2005 - 2006 Relationin respiratory failure to adiposaitocain and effect of rehabilitation

2005 - 2006 Elucidation of the mechanism that therapeutic exercise effectively inhibits the aggravation of progressive renal disease in diabetes mellitus.

2004 - 2005 微弱電気刺激による筋力維持・廃用防止と血管新生法の確立:リハビリ物理療法の新展開

2004 - 2005 AUTONOMIC AND ENDOCRINE SYSTEM WHICH HAVE FAVORABLE EFFECTS ON EXERCISE CAPASITY OR MUSCLE STRENGTH

2004 - 2005 Mechanism of renoprotective effect of exercise training : Role of renal cytochrome P-450 metabolism of arachidonic acid

2004 - 2005 Establishment of the renal rehabilitation : Elucidation of the mechanism that therapeutic exercise effectively inhibits the aggravation of progressive renal disease.

2003 - 2005 A study on educational program of cardiac rehabilitation in patient with coronary artery disease

2003 - 2004 神経疾患における呼吸器合併症の予防に関する研究:超小型呼吸モニタ装置の開発と応用

2003 - 2004 Elucidation of the mechanism that rehabilitation therapeutic exercise protects myocardium

2003 - 2004 Fundamental verification to establish evidences among pulmonary rehabilitation.

2002 - 2003 電子ビームCT肺気腫呼吸動画像による気道及び肺実質の病的動態の解析と臨床応用

2002 - 2003 The optimal exercise method and analysis of carbohydrate & fat metabolism of the disabled

2002 - 2003 The role of chronic exercise in the preservation of the renal function in renal failure models

2002 - 2003 the elucidation of the mechanisms of angiogenesia and cardiovascular hypertrophy and the application of angiogenesis by therapeutic electrical stimulation

2002 - 2003 EFFECTS OF EXERCISE AND DRUGS TREATMENT ON CARDIOVASCULAR DISEASE

2000 - 2001 The elucidation of the mechanisms of cardiovascular hypertrophy and hyperplasia and the establishment of angiogenesis by therapeutic electrical stimulation

1999 - 1999 ナトリウム代謝感受性遺伝子多型および変異の検査同定法の確立とその臨床応用

1998 - 1999 Introduction and Usefulness of a newly-developed instrument for monitoring cardiopulmonary and postural parameters in cardiopulmonary rehabilitation.

1998 - 1999 Mechanisms of the hypertrophy/hyperplasia of heart/vessels and the cardio-reno-protection to ischemia

1998 - 1998 脳卒中リハビリテーションの効果の新しい解析法:連続的呼吸循環姿勢計測装置の応用

1996 - 1997 Mechanisms of the cardiac/vasculor hypertrophy and cardio-protection

1994 - 1995 The role of tissue renin-angiotensin system on cardiovascular and renal hypertrophy/hyperplasia

1993 - 1993 冠血管新生・心肥大・血管把厚に果たす組織レニン・アンジオテンシン(R-A)系の関与

1992 - 1993 Characterization, localization and quantification of neutral metalloendopeptidase, the degradative enzyme for atrial natriuretic peptide

1991 - 1993 Intracellular signal transduction and functional regulation along the nephron segmnents.

1992 - 1992 冠血管新生および代償性心筋増殖・肥大に果たす心臓レニン・アンジオテンシン系の関与

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Misa Miura, Masahiro Kohzuki, Chie Saito, Satoshi Sakai, Hisashi Sugaya, Shingo Koyama, Yasushi Matsui, Tohru Sakuma, Osamu Ito, Kunihiro Yamagata. Systemic Capillary Responses to Acute Exercise in Hypertensive Seniors: Insights from a Single-Center Pilot Study. Journal of Clinical Medicine. 2024. 13. 10. 2818-2818
Toshimi Sato, Masahiro Ono, Keiichi Kawamura, Wakako Naganuma, Namiko Shishito, Shinichiro Morishita, Yuichiro Sasamoto, Masahiro Kohzuki. Impact of moderate to vigorous intensity physical activity on change in renal function in patients after acute myocardial infarction. Heart and vessels. 2024
Asako Namai-Takahashi, Junta Takahashi, Yoshiko Ogawa, Akihiro Sakuyama, Lusi Xu, Takahiro Miura, Masahiro Kohzuki, Osamu Ito. Effects of Exercise Training on Mitochondrial Fatty Acid β-Oxidation in the Kidneys of Dahl Salt-Sensitive Rats. International Journal of Molecular Sciences. 2023. 24. 21. 15601-15601
三浦平寛, 上月正博. 【CKDと高血圧の関連性を再考する】CKDにおけるDTx(デジタルセラピューティクス). 腎臓内科. 2023. 18. 4. 453-458
徐ろ思, 三浦平寛, 上月正博, 伊藤修. Dahl食塩感受性および抵抗性ラットにおける血圧と腎障害への高フルクトース摂取による影響. 日本内分泌学会雑誌. 2023. 99. 3. 718-718

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伊藤修, 徐路思, 三浦平寛, 高橋麻子, 上月正博. 高フルクトース摂取下のDahl食塩感受性ラットにおける選択的PPARαモジュレーターpemafibrateの腎保護効果. 腎と脂質研究会プログラム・抄録集. 2023. 35th
三浦美佐, 本間みどり, 海老原覚, 平山陽, 上月正博. ベルト電極式骨格筋電気刺激法が高齢血液透析患者の運動機能に及ぼす影響について. 日本腎臓リハビリテーション学会学術集会プログラム・抄録集. 2023. 13th
ジョロシ, 仇嘉禾, 三浦平寛, 高橋麻子, 上月正博, 伊藤修, 伊藤修. 高フルクトース摂取下Dahl食塩感受性ラットにおける長期的運動の降圧や腎保護効果. 日本腎臓リハビリテーション学会学術集会プログラム・抄録集. 2022. 12th
佐藤聡見, 上月正博. 心疾患と腎臓リハビリテーション. 日本腎臓リハビリテーション学会学術集会プログラム・抄録集. 2022. 12th
三浦平寛, 作山晃裕, 徐ろ思, 仇嘉禾, 高橋麻子, 小川佳子, 上月正博, 伊藤修. Dahl食塩感受性ラットにおける高食塩食摂取による腎内xanthine oxidase活性化とfebuxostatの効果. 腎と脂質研究会プログラム・抄録集. 2022. 34th

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ねころんで読める新しいリハビリ: 内部障害リハビリテーションの驚くべき効果
メディカ出版 2018 ISBN:4840465401
名医の身心ことばセラピー
さくら舎 2017 ISBN:4865811311
リハビリテーション医学 VOL.17 内部障害のリハビリテーション (医学教育シリーズ)
医学映像教育センター 2017 ISBN:4862435378
新編内部障害のリハビリテーション第2版
医歯薬出版 2017 ISBN:4263215788
「CLINICAL REHABILITATION」別冊新版リハビリテーション医学Q&A 専門医を目指して
医歯薬出版 2017

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Localization of (pro)renin receptor in the nephron segments of rat kidney
(12th China-Japan Joint Symposium on Hypertension 2010 2010)
Exercise training upregulates nitric oxide synthases in the kidney of rats with chronic heart failure
(23rd Scientific Meeting of International Society of Hypertension 2010)
Endogenous hydrogen peroxide upregulates the expression of nitric oxide synthase in spontaneously hypertensive rats
(23rd Scientific Meeting of International Society of Hypertension 2010)
Expression of (pro)renin receptor in the nephron segments of rat kidney; regulation by dehydration
(23rd Scientific Meeting of International Society of Hypertension 2010)
Endogenous hydrogen peroxide upregulates the expression of nitric oxide synthase in spontaneously hypertensive rats
(12th China-Japan Joint Symposium on Hypertension 2010 2010)

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- 1981 Tohoku University Faculty of Medicine 医学科

医学博士 (Tohoku University)

2010 - 現在東北大学大学院医学系研究科創生応用医学研究センター先進統合腎臓科学教授(併任)
2002 - 現在東北大学病院リハビリテーション部部長(併任)
2000 - 現在東北大学大学院内部障害リハビリテーション科科長
2000 - 現在東北大学大学院医学系研究科障害科学専攻内部障害学分野教授
2008 - 2015 東北大学大学院医学系研究科障害科学専攻長(併任)

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2011/10 - 現在日本腎臓リハビリテーション学会理事長
2011/10 - 現在日本腎臓リハビリテーション学会理事長
2007/07 - 現在日本運動療法学会理事
2007/07 - 現在日本運動療法学会理事
2006/06 - 現在日本リハビリテーション医学会理事

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2018 - チェコハンス・セリエ記念メダル受賞
2007 - 日本ストーマ排泄リハビリテーション学会学会長賞
2004/05 - 日本リハビリテーション医学会日本リハビリテーション医学会」2003年度最優秀論文賞
2003/05 - 日本リハビリテーション医学会「日本リハビリテーション医学会」2002年度奨励賞

日本不整脈学会(2011/04-) , 日本腎臓リハビリテーション学会(2011/10- 理事長) , 日本リハビリテーション医学会(2004/06-2006/05 評議員) , 日本内分泌学会(東北支部)(2005/04- 評議員) , 日本循環器学会(東北支部)(2003/04- 評議員) , 日本内科学会(東北支部)(2001/04- 評議員) , 日本運動療法学会(2007/07- 理事) , 日本心血管内分泌代謝学会(2002/10- 評議員) , 日本心不全学会(2000/10- 評議員) , 日本腎臓学会(1997/06- 評議員) , 日本高血圧学会(1998/10- 評議員) , 日本摂食・嚥下リハビリテーション学会(2005/09- 評議員) , 日本呼吸ケア・リハビリテーション学会(2003/07- 評議員) , 日本心臓リハビリテーション学会(2003/07- 評議員) , 国立大学理学療法・リハビリ部門代表者会議(2004/09- 編集委員長) , 国立大学理学療法・リハビリ部門代表者会議(2005/04- 会長) , 日本リハビリテーション医学会(2006/04- 編集委員長) , 日本リハビリテーション医学会(2006/06- 理事)