Inoue Osamu

イノウエオサム | Inoue Osamu

Affiliation and department：

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (2)：核薬学 , Radiopharmacology

Research theme for competitive and other funds (21)：

2011 - 2013 Evaluation of 14C(11C)-Benzyl acetate as a potential probe for the measurement of glial metabolism.
2007 - 2009 Study on functional roles of PBR (TSPO) in glia and myocardium
2007 - 2008 超高比放射能標識リガンドによる生体超微量現象の解明
2007 - 2008 Evaluation of brain and whole-body micro-dosing pharmacokinetics of <11>^C-labeled donepezil in rats by means of planar positron imaging system
2006 - 2008 Changes in brain functional images by the electroconvulsive therapy on severe depressive patients

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Papers (55)：

Miho Shukuri, Miyu Uchino, Takafumi Sakamaki, Satoru Onoe, Rie Hosoi, Kenichiro Todoroki, Yasushi Arano, Toshihiro Sakai, Hiromichi Akizawa, Osamu Inoue. Ex vivo imaging and analysis of ROS generation correlated with microglial activation in rat model with acute neuroinflammation induced by intrastriatal injection of LPS. Biochemical and biophysical research communications. 2021. 584. 101-106
Rie Hosoi, Yuka Fujii, Ohba Hiroyuki, Miho Shukuri, Shingo Nishiyama, Masakatsu Kanazawa, Kenichiro Todoroki, Yasushi Arano, Toshihiro Sakai, Hideo Tsukada, et al. Evaluation of intracellular processes in quinolinic acid-induced brain damage by imaging reactive oxygen species generation and mitochondrial complex I activity. EJNMMI Research. 2021. 11. 1
Rie Hosoi, Sota Sato, Miho Shukuri, Yuka Fujii, Kenichiro Todoroki, Yasushi Arano, Toshihiro Sakai, Osamu Inoue. A Simple Ex Vivo Semiquantitative Fluorescent Imaging Utilizing Planar Laser Scanner: Detection of Reactive Oxygen Species Generation in Mouse Brain and Kidney. Molecular Imaging. 2019. 18. 1-7
Osamu Inoue, Toshiyuki Sato, Kaoru Kobayashi, Antony Gee, Miho Shukuri, Ming-Rong Zhang. Unexpected decrease in in vivo binding of [3H]QNB in the mouse cerebral cortex in the developing brain - A comparison with [11C]NMPB. Nuclear medicine and biology. 2018. 67. 15-20
Maki Okada, Kazuhiko Yanamoto, Tomohiko Kagawa, Keiko Yoshino, Rie Hosoi, Kohji Abe, Ming-Rong Zhang, Osamu Inoue. Kinetic study of benzyl [1-C-14]acetate as a potential probe for astrocytic energy metabolism in the rat brain: Comparison with benzyl [2-C-14]acetate. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2016. 36. 2. 442-450

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MISC (94)：

T. Itoh, K. Abe, O. Inoue, J. Hong, V. W. Pike, R. B. Innis, M. Fujita. The effect of cAMP dependent protein kinase activator and inhibitor on [C-11]rolipram binding to phosphodiesterase 4 in conscious rats. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2009. 29. S13-S14
Rie Hosoi, Yasuyo Matsuyama, Shin-ichiro Hirose, Yutaka Koyama, Toshio Matsuda, Antony Gee, Osamu Inoue. Characterization of C-14-acetate uptake in cultured rat astrocytes. BRAIN RESEARCH. 2009. 1253. 69-73
Sotaro Momosaki, Rie Hosoi, Tomoya Sanuki, Kenichiro Todoroki, Masatoshi Yamaguchi, Antony Gee, Osamu Inoue. [C-14]Benzyl acetate is a potential radiotracer for the measurement of glial metabolism in the rat brain. NUCLEAR MEDICINE AND BIOLOGY. 2007. 34. 8. 939-944
畑澤順, 下瀬川恵久, 今泉昌男, 高沢正志, 木村泰之, 梶本勝文, 加藤弘樹, 田中真希子, 井上修, 細井理恵. 脳卒中のイメージングマクロからミクロまで神経細胞のイメージング、グリア細胞のイメージング. 脳卒中. 2007. 29. 6. 832-832
畑澤順, 下瀬川恵久, 今泉昌男, 高沢正志, 木村泰之, 梶本勝文, 加藤弘樹, 田中真希子, 井上修, 細井理恵. 脳卒中のイメージング:マクロからミクロまで神経細胞のイメージング、グリア細胞のイメージング. 脳卒中. 2007. 29. 2. 205-205

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Books (2)：

核医学医用放射線科学講座-9
医歯薬出版 1996
UPPER 放射線医学核医学
南山堂

Education (2)：

- 1971 Kyushu University School of Pharmaceutical Sciences
- 1971 Kyushu University Faculty of Pharmaceutical Science

Professional career (1)：

(BLANK)

Committee career (1)：

日本核医学会評議員

Association Membership(s) (4)：

日本神経化学会 , 日本神経精神薬理学会 , 日本核医学会 , 日本薬学会

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