Kobara Miyuki

Research field (1)： Cardiology

Research keywords (5)： cardio oncology , autophagy , apoptosis , Mitochondrial quality control , Heart failure

Research theme for competitive and other funds (20)：

2022 - 2025 Molecular fingerprint imaging to Alzheimer's disease development to produce by periodontal disease bacteria using raman spectroscopy
2021 - 2024 細胞外ミトコンドリア放出を伝達ツールとした心不全病態悪化の検討及び治療への応用
2020 - 2023 バイオセラミックス・コーティングによる骨伝導性の強化とインプラント周囲炎の予防
2018 - 2019 口腔顔面領域の疾患に対する革新的診断技術と治療法の開発
2012 - 2017 バイオメタルと生体反応の連関解明に基づいた疾患治療ファルマコメトロミクスの確立(分担)

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Papers (73)：

Miyuki Kobara, Tatsuya Shiraishi, Kazuki Noda, Hiroe Toba, Tetsuo Nakata. Eicosapentaenoic Acid Preserves Mitochondrial Quality and Attenuates Cardiac Remodeling After Myocardial Infarction in Rats. Journal of Cardiovascular Translational Research. 2023
Miyuki Kobara, Toshihiro Amano, Hiroe Toba, Tetsuo Nakata. Nicorandil Suppresses Ischemia-Induced Norepinephrine Release and Ventricular Arrhythmias in Hypertrophic Hearts. Cardiovascular drugs and therapy. 2023. 37. 1. 53-62
Miyuki Kobara, Hiroe Toba, Tetsuo Nakata. Roles of autophagy in angiotensin II-induced cardiomyocyte apoptosis. Clinical and experimental pharmacology & physiology. 2022. 49. 12. 1342-1351
Giuseppe Pezzotti, Miyuki Kobara, Tamaki Nakaya, Hayata Imamura, Tomoya Fujii, Nao Miyamoto, Tetsuya Adachi, Toshiro Yamamoto, Narisato Kanamura, Eriko Ohgitani, et al. Raman Metabolomics of Candida auris Clades: Profiling and Barcode Identification. International journal of molecular sciences. 2022. 23. 19
Tetsuya Adachi, Nao Miyamoto, Hayata Imamura, Toshiro Yamamoto, Elia Marin, Wenliang Zhu, Miyuki Kobara, Yoshihiro Sowa, Yoshiro Tahara, Narisato Kanamura, et al. Three-Dimensional Culture of Cartilage Tissue on Nanogel-Cross-Linked Porous Freeze-Dried Gel Scaffold for Regenerative Cartilage Therapy: A Vibrational Spectroscopy Evaluation. International journal of molecular sciences. 2022. 23. 15

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MISC (216)：

谷島旭, 小原幸, 鳥羽裕恵, 中田徹男. 心筋細胞低酸素再酸素化障害に対するホノキオールのサーチュイン3を介した保護効果. 日本薬理学会年会プログラム抄録集. 2022
Hiroe Toba, Miyuki Kobara, Tetsuo Nakata. SPARC is induced at the early stage of vascular endothelial dysfunction to compansate inflammation in DOCA-salt hypertensive rats. 2022
小原幸、鳥羽裕恵、中田徹男. Nicorandil suppresses ischemia-induced cardiac norepinephrine enhancement and ventrocular arrhythmiqas in pressure overload-induced hypertrophic hearts. The 29th Scientific Meeting of the International Sciety of Hypertension. 2022
長井皓平、小原幸、赤倉章仁、清水美乃莉、鳥羽裕恵、中田徹男. GLP-1 受容体作動薬の高血糖誘導性糸球体足細胞障害無に対する影響. 第141回日本薬理学会近畿部会プログラム抄録集. 2022
SPARK and ADAMTS1 are induced as anti-inflammatory factor ar the early stage of vascular endothelial injury in DOCA-salt hypertensive rats. 2022

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Patents (1)：

心疾患治療剤

Education (2)：

- 1989 Kyoto Prefectural University of Medicine
- 1989 Kyoto Prefectural University of Medicine Faculty of Medicine

Professional career (1)：

Doctor of Medicine

Association Membership(s) (6)：

Japanese Association of Cardiovascular Pharmacology , Japanese Society of Hypertension , American Physiological Society , 国際心臓研究年会(日本部会) , 日本内科学会 , 日本循環器学会

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