Rchr
J-GLOBAL ID:200901070348712612   Update date: Sep. 15, 2024

Tonozuka Takashi

Tonozuka Takashi
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://web.tuat.ac.jp/~seika/
Research field  (3): Applied molecular and cellular biology ,  Applied biochemistry ,  Structural biochemistry
Research keywords  (7): cellulase ,  biomass ,  beta-fructofuranosidase ,  alpha-glucosidase ,  amylase ,  oligosaccharide ,  carbohydrate-active enzyme
Research theme for competitive and other funds  (12):
  • 2022 - 2025 Characteristic approach in hemicellulase which is important for biodegradation of woody biomass.
  • 2022 - 2025 重症型ブドウ球菌感染症の成立に関わる外毒素の基質認識機構の解明と予防戦略
  • 2020 - 2023 Elucidation of the structure-function relationship and the sugar-recognition mechanism of novel mutidomain transglucosidases acting on starch
  • 2016 - 2018 担子菌のファミリー131に属する二種類のタンパク質の構造と機能の解明
  • 2014 - 2015 ファミリー131に属する機能未知酵素がバイオマス分解に果たす役割の解明
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Papers (121):
  • Shu Sato, Rokaia F. Ragab, Xu Guo, Ahmed Elfadadny, Takuma Kozono, Atsushi Nishikawa, Koji Nishifuji, Takashi Tonozuka. Crystal structure of exfoliative toxin D from Staphylococcus aureus. Biochemical and Biophysical Research Communications. 2024. 733. 150689-150689
  • Yuki Miyasaka, Kohei Yokoyama, Takuma Kozono, Yoshikazu Kitano, Takatsugu Miyazaki, Masayoshi Sakaguchi, Atsushi Nishikawa, Takashi Tonozuka. Structural basis for the recognition of α-1,6-branched α-glucan by GH13_47 α-amylase from Rhodothermus marinus. Proteins: Structure, Function, and Bioinformatics. 2024
  • Shuntaro Nakamura, Rikuya Kurata, Takashi Tonozuka, Kazumi Funane, Enoch Y. Park, Takatsugu Miyazaki. Bacteroidota polysaccharide utilization system for branched dextran exopolysaccharides from lactic acid bacteria. Journal of Biological Chemistry. 2023. 299. 7. 104885-104885
  • Ding Li, Yuki Miyasaka, Arisa Kubota, Takuma Kozono, Yoshikazu Kitano, Nobumitsu Sasaki, Tadashi Fujii, Takumi Tochio, Yoshihiro Kadota, Atsushi Nishikawa, et al. Characterization and alteration of product specificity of Beijerinckia indica subsp. indica β-fructosyltransferase. Bioscience, Biotechnology, and Biochemistry. 2023
  • Takuma Kozono, Chifuyu Jogano, Wataru Okumura, Hiroyuki Sato, Hitomi Matsui, Tsubasa Takagi, Nobuaki Okumura, Toshifumi Takao, Takashi Tonozuka, Atsushi Nishikawa. Cleavage of the Jaw1 C-terminal region enhances its augmentative effect on the Ca2+ release via IP3 receptors. Journal of Cell Science. 2023. 136. 4
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MISC (33):
  • 窪田有紗, 川合礼華, 松浦明香, 小薗拓馬, 西河淳, 藤井匡, 栃尾巧, 殿塚隆史. Alteration of substrate preference of GH32 β-fructofuranosidase from the honeybee gut bacterium Frischella perrara. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
  • 窪田有紗, 川合礼華, 松浦明香, 藤井匡, 栃尾巧, 西河淳, 殿塚隆史. Crystal structure of a GH32 fructooligosaccharide-hydrolyzing enzyme in complex with fructose. 量子ビームサイエンスフェスタ(Web). 2021. 2020
  • 小薗 拓馬, 佐藤 展之, 奥村 航, 岩佐 和志, 城ヶ野 千冬, 中野 美和[田村], 河村 由紀, 殿塚 隆史, 西河 淳. Jaw1のN末ドメインによる多量体形成の分子内制御機構の解明. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [3T14a-03]
  • 石川涼一, 奥山舜朔, 砂川直輝, 五十嵐圭日子, 西河淳, 吉田誠, 殿塚隆史. Structural analysis of CcGH131B from Coprinopsis cinerea in complex with cellobiose. 量子ビームサイエンスフェスタ(Web). 2018. 2017
  • 石川涼一, 吉田誠, 砂川直輝, 五十嵐圭日子, 西河淳, 殿塚隆史. 担子菌Coprinopsis cinerea由来CcGH131Bと各種リガンドとのX線結晶構造解析. 日本結晶学会年会講演要旨集. 2018. 2018
more...
Books (3):
  • Traffic of Botulinum toxin complex: the crystal structure and the role of toxin complex
    "Glycoscience: Biology and Medicine" (Endo, T., Seeberger, P.H., Hart, G.W., Wong, C.-H. and Taniguchi, N., eds.), Springer 2015
  • Enzymes for cellulosic biomass conversion
    "Research Approaches to Sustainable Biomass Systems" (Tojo, S. and Hirasawa, T., eds.), Academic Press Elsevier 2013
  • Crystal structure of the pullulan-hydrolyzing alpha-amylase from Thermoactinomyces vulgaris R-47, and manipulation of the substrate specificities
    "Recent Advances in Carbohydrate Bioengineering" (Gilbert H.J., Henrissat, B. and Svensson, B., eds.), The Royal Society of Chemistry 1999
Lectures and oral presentations  (104):
  • 担子菌Coprinopsis cinerea由来CcGH131Bと各種リガンドとのX線結晶構造解析
    (日本結晶学会 2018)
  • プルラン分解α-アミラーゼTVA Iの改変酵素におけるドメインBのコンフォメーション変化
    (日本応用糖質科学会 2018)
  • Flavobacterium johnsoniae由来GH31デキストラナーゼFjDex31A改変酵素の性質解析
    (日本応用糖質科学会 2018)
  • 担子菌のGH131に属する酵素の立体構造と機能の解析
    (セルラーゼ研究会 2018)
  • Aspergillus kawachii由来β-フルクトフラノシダーゼの改変による1-ケストース生産能向上と改変酵素の構造解析
    (日本農芸化学会 2018)
more...
Works (1):
  • CAZypedia, Glycoside Hydrolase Family 49 http://www.cazypedia.org/
    2010 - 2010
Professional career (2):
  • 修士(農学)
  • 博士(農学)
Committee career (9):
  • 2020/04 - 現在 日本応用糖質科学会東日本支部 企画委員
  • 2016 - 現在 日本応用糖質科学会 評議員
  • 2009 - 現在 日本応用糖質科学会東日本支部 理事
  • 2007 - 現在 応用糖質科学誌 編集委員
  • 2021/04 - 2022/09 日本応用糖質科学会 2022年度大会実行委員会場担当
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Awards (3):
  • 2012/06 - FEBS Journal Molecular Enzymology Virtual Issue "Comparison of the structural changes in two cellobiohydrolases, CcCel6A and CcCel6C, from Coprinopsis cinerea"
  • 2008/09 - Japanese Society of Applied Glycoscience Distinguished Young Scientist Award "Study on structure and function of enzymes acting on pullulan and related saccharides"
  • 2006/06 - Amano Enzyme Research encouragement award "Crystal structure of isopullulanase and elucidation of its reaction mechanism"
Association Membership(s) (6):
日本農芸化学会 ,  日本生化学会 ,  日本応用糖質科学会 ,  日本生物工学会 ,  日本結晶学会 ,  FCCA
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