Rchr
J-GLOBAL ID：200901070603455742   Update date: Mar. 25, 2024

Miyagawa Shuji

ミヤガワ シュウジ | Miyagawa Shuji
Affiliation and department：
Osaka University Research Institute for Microbial Diseases Research Institute for Microbial Diseases

About Osaka University Research Institute for Microbial Diseases Research Institute for Microbial Diseases


Job title： Associate Professor
Other affiliations (1)：
  • 明治大学  研究・知財戦略機構   客員教授
Research field  (5)： General surgery, pediatric surgery ,  General surgery, pediatric surgery ,  General surgery, pediatric surgery ,  General surgery, pediatric surgery ,  Immunology
Research keywords  (4)： Complement ,  Xenotransplantation ,  glycobiology ,  臓器移植学
Research theme for competitive and other funds  (30)：
  • 2021 - 2024 Verification of gene-edited pig production method from Japan
  • 2018 - 2021 Control of porcine endogenous retrovirus for regenerative medicine using pigs as a scaffold and development of bio-organs
  • 2016 - 2019 The development for the stable high expression of numerous transgenes.
  • 2014 - 2017 MDSC-induced suppression of xenogeneic rejection in combination with gene-modification in porcine endotherial cells
  • 2014 - 2016 Study for the knockout of porcine endothelial retrovirus (PERV)
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Papers (98)：
  • Keigo Iemitsu, Rieko Sakai, Akira Maeda, Katarzyna Gadomska, Shuhei Kogata, Daiki Yasufuku, Jun Matsui, Kazunori Masahata, Masafumi Kamiyama, Hiroshi Eguchi, et al. The hybrid CL-SP-D molecule has the potential to regulate xenogeneic rejection by human neutrophils more efficiently than CD47. Transplant Immunology. 2024. 84. 102020-102020
  • Keigo Iemitsu, Rieko Sakai, Akira Maeda, Katarzyna Gadomska, Shuhei Kogata, Daiki Yasufuku, Jun Matsui, Kazunori Masahata, Masafumi Kamiyama, Hiroshi Eguchi, et al. The hybrid CL-SP-D molecule has the potential to regulate xenogeneic rejection by human neutrophils more efficiently than CD47. Transplant immunology. 2024. 84. 102020-102020
  • 角田 洋一, 家光 恵心, 前田 晃, 松村 聡一, 深江 彰太, 田中 亮, 中澤 成晃, 山中 和明, 古形 修平, 神山 雅史, et al. ヒトCD47及びCL-SP-Dによるヒト好中球誘導性異種拒絶反応の抑制作用の検討. 移植. 2023. 58. 総会臨時. 316-316
  • 宮川 周士. 異種移植の現状. 医学のあゆみ. 2022. 283. 4
  • Shuhei Kogata, Pei-Chi Lo, Akira Maeda, Chizu Okamatsu, Kazuki Sato, Riho Yamamoto, Tomoko Haneda, Tomohisa Yoneyama, Chiyoshi Toyama, Hiroshi Eguchi, et al. Suppression of macrophage-mediated xenogeneic rejection by the ectopic expression of human CD177. Transplant Immunology. 2022. 74. 101663-101663
ｍore...
MISC (218)：
  • MIYAGAWA Shuji. REMINISCENCES OF XENOTRANSPLANTATION STUDIES Reminiscences of xeno pioneers. [Recollections of Pioneers in Xenotransplantation Research Edit by David K.C. Cooper MD, PhD, FRCS]. 2019. 241-266
  • Shuji Miyagawa, Akira Maeda, Hiroshi Eguchi, Rieko Sakai, Pei-Chi Lo, Hantang Wang, Chihiro Takakura, Tasuku Komama, Rei Matsuura, Hiroomi Okuyama. The State of Xenotransplantation. [Xenotransplantation New Insights] Open access Publisher INTECH. 2017. 3-10
  • Human DAF suppresses macrophage-mediated xenogeneic cytotoxicity and phagocytosis through the binding of SCR-4 to the inhibitory receptor. 2016. 53. 1. 45-47
  • Akira Maeda, Rieko Sakai, Hiroshi Eguchi, Peichi Lo, Thuy-vy Choi, Mayumi Asada, Kazuaki Yamanaka, Rei Matsuura, Kengo Nakahata, Hiroomi Okuyama, et al. Therapeutic potential of monocytic MDSCs from peripheral blood monocytes in transplant rejection, Macrophage. 2015. e1069
  • Akira Maeda, Hiroshi Eguchi, Takuji Kawamura, Hiroomi Okuyama, Shuji Miyagawa. [Glycoantigen and Xenotransplantation 182]. Glycoscience: Biology and Medicine. 2014. 1483-1491
ｍore...
Lectures and oral presentations  (12)：
  • Macrophages in xenotransplantation
    (ATW2022)
  • The suppression of macrophage-mediated intestinal transplant rejection by C5a receptor antagonist.
    (The Transplantation Society 2022)
  • Effect of a C5a receptor antagonist on macrophage function in an intestinal transplant rat model
    (The Transplantation Society)
  • ヒトSP-Aによるマクロファーッジ誘導異種移植拒絶反応の抑制
    (2022)
  • ヒトSP-Aによる好中球誘導異種拒絶反応抑制効果の検討
    (2022)
ｍore...
Works (5)：
  • 臓器移植医学に応用するためのブタの品種改良の増殖に関する研究
    2001 - 2005
  • 異種移植における遅延型拒絶反応の抑制。
    2004 -
  • 異種移植におけるブタレトロウイルス制御の試み。
    2004 -
  • 循環器病研究受託
    2004 -
  • 異種移植におけるNK細胞の制御
    2004 -
Professional career (1)：
  • (BLANK) (Osaka University)
Work history (3)：
  • 2019/04 - 現在 大阪大学 微生物病研究所 遺伝情報実験センター 遺伝子機能解析分野 招聘研究員
  • 2018/04 - 現在 Meiji University Organization for the Strategic Coordination of Research and Intellectual Properties
  • 1998/04 - 2019/03 Osaka University Graduate School of Medicine
Awards (3)：
  • 1993 - 大阪対ガン協会 ガン研究奨励賞
  • 1993 - 財団法人上原記念生命科学財団 研究奨励賞
  • 1992 - 財団法人かなえ新薬研究会 かなえ医学奨励賞
Association Membership(s) (8)：
THE JAPANESE ASSOCIATION FOR COMPLEMENT RESEARCH ,  国際異種移植学会 ,  国際移植学会(The Transplantation Society) ,  日本移植学会 ,  日本外科学会 ,  日本小腸移植研究会 ,  日本膵・膵島移植研究会 ,  日本異種移植研究会
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