Kato Y, Tabata H, Sato K, Nakamura M, Saito I, Nakanishi T. Adenovirus vectors expressing eight multiplex guide RNAs of CRISPR/Cas9 efficiently disrupted diverse hepatitis B virus gene derived from heterogeneous patient. Int J Mol Sci. 2021. 22. 10570
Tomoko Nakanishi, Aya Maekawa, Mariko Suzuki, Hirotaka Tabata, Kumiko Sato, Mai Mori, Izumu Saito. Construction of adenovirus vectors simultaneously expressing four multiplex, double-nicking guide RNAs of CRISPR/Cas9 and in vivo genome editing. Scientific reports. 2021. 11. 1. 3961-3961
Yamazaki M, Matsda N, Matoba K, Kondo S, Kanegae Y, Saito I, Nomoto A. Acetophenone 4-nitrophenylhydrazone inhibits hepatitis B virus replication by modulating capsid assembly. Virus Res. 2021. 306. 198565
S. Kondo, A. Maekawa, M. Suzuki, Y. Kanegae, I. Saito. First-generation adenovirus vector expresses viral-associated (VA) RNAs that disturb cellular gene expressions. HUMAN GENE THERAPY. 2013. 24. 12. A79-A79
Saki Kondo, Yumi Kanegae, Nic Jones, Izumu Saito. A role of microRNAs for sensitization to cisplatin in ovarian cancer cell lines. HUMAN GENE THERAPY. 2012. 23. 10. A96-A96
New virus vectors and their methods of production and use
Production methods of vectors containing DNA cassettes connecting multiplex expressing units
Education (2):
1978 - 1982 The University of Tokyo, D.Med.Sci. (Ph.D) Department of Tumor Viruses, Institute of Medical Science Graduate Course of Medicine
1972 - 1978 The University of Tokyo (license of medical doctor obtained) Medical School of Medicine
Professional career (1):
D.Med.Sci.(Ph.D.) (The University of Tokyo)
Work history (8):
2021 - 現在 Juntendo University Graduate School of Medicine
2020 - 2021 National Center for Child Health and Development
2017 - 2020 Institute of Microbial Chemistry Department of Virology Team Leader
2000 - 2017 The University of Tokyo Laboratory of Molecular Genetics, Institute of Medical Science Professor
1991 - 2000 The University of Tokyo Laboratory of Molecular Genetics, Institute of Medical Science, Associate Professor, Facility Head
1987 - 1991 National Institute of Health Laboratory of Hepatitis, Department of Enteroviruses Chief Researcher
1982 - 1987 The University of Tokyo Department of Bacteriology, Faculty of Medicine Assistant Professor
1984 - 1986 Imperial Cancer Research Fund, London, UK Research Fellow
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Committee career (2):
2021 - 2022 Ministry of Education and Science Chair, Recombinant DNA Advisory Committee
- 2014 The 20th Japan Society Gene Therapy Annual Meeting President
Association Membership(s) (5):
Japan Society of Gene and Cell Therapy
, Japanese Society for Genome Editing
, Japan Society of Molecular Biology
, Japanese society for Virology
, The Japanese Cancer Association