Rchr
J-GLOBAL ID：200901071260889438
Update date: Feb. 01, 2024
Kunimasa Kazuhiro
クニマサ カズヒロ | Kunimasa Kazuhiro
Affiliation and department：
Job title：
Postdoctoral Scientist
Research field (6)：
Tumor biology
, Pathobiochemistry
, Food sciences
, Cell biology
, Molecular biology
, Laboratory animal science
Research keywords (10)：
Mitochondria
, Cancer metabolism
, Unfolded protein response
, ER stress
, Tumor microenvironment
, 生活習慣病発症ラットモデル
, 生活習慣病
, がん
, 血管新生
, 機能性食品
Research theme for competitive and other funds (5)：
- 2022 - 2025 薬剤感受性及びオミクスデータを用いたミトコンドリア代謝脆弱性因子の同定と治療応用
- 2016 - 2022 Development of innovative methods for cancer therapy based on DDS
- 2018 - 2021 Molecular basis of oncogenic mutation-associated resistance to endoplasmic reticulum stresses and their applications to cancer chemotherapy
- 2009 - 2012 A comprehensive search for antiangiogenic food factors and molecular biological analysis of their mode of inhibition
- 2009 - 2012 Cancer Preventive Effects of Resveratrol Oligomer-Rich Food Factors with an Antiangiogenic Activity
Papers (28)：
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Kazuhiro Kunimasa, Chika Ikeda-Ishikawa, Yuri Tani, Satomi Tsukahara, Junko Sakurai, Yuka Okamoto, Masaru Koido, Shingo Dan, Akihiro Tomida. Spautin-1 inhibits mitochondrial complex I and leads to suppression of the unfolded protein response and cell survival during glucose starvation. Scientific reports. 2022. 12. 1. 11533-11533
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Yu Kato, Kazuhiro Kunimasa, Mizuki Takahashi, Ayaka Harada, Ikuko Nagasawa, Masanori Osawa, Yoshikazu Sugimoto, Akihiro Tomida. GZD824 Inhibits GCN2 and Sensitizes Cancer Cells to Amino Acid Starvation Stress. Molecular pharmacology. 2020. 98. 6. 669-676
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Ikuko Nagasawa, Masaru Koido, Yuri Tani, Satomi Tsukahara, Kazuhiro Kunimasa, Akihiro Tomida. Disrupting ATF4 Expression Mechanisms Provides an Effective Strategy for BRAF-Targeted Melanoma Therapy. iScience. 2020. 23. 4. 101028-101028
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Naoki Okamura, Toshiro Ohta, Kazuhiro Kunimasa, Yoshihiro Uto, Shigenori Kumazawa. Antiangiogenic Activity of Flavonols in Chorioallantoic Membrane (CAM) Assay. FOOD SCIENCE AND TECHNOLOGY RESEARCH. 2020. 26. 6. 891-896
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Yu Kato, Kazuhiro Kunimasa, Yoshikazu Sugimoto, Akihiro Tomida. BCR-ABL tyrosine kinase inhibition induces metabolic vulnerability by preventing the integrated stress response in K562 cells. Biochemical and biophysical research communications. 2018. 504. 4. 721-726
ｍore...
MISC (2)：
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国政 和宏, 太田 敏郎, 谷 央子, 加藤 榮信, 江口 良二, 森 英樹, 森 真理, 立藤 智基, 家森 幸男. メリンジョ(Gnetum gnemon L.)種子由来レスベラトロール2量体の血管新生抑制作用. 日本薬学会年会要旨集. 2011. 131年会. 2. 205-205
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国政 和宏, 江口 良二, 太田 敏郎, 加治 和彦, 森 英樹, 森 真理, 立藤 智基, 家森 幸男. インドネシア果実メリンジョから単離されたレスベラトロール2量体グネチンCの血管新生抑制作用(Identification of Gnetin C, a Resveratrol Dimer, Isolated from Indonesian Fruit Melinjo (Gnetum Gnemon L.) as a Novel and Potent Angiogenesis Inhibitor). 日本生化学会大会プログラム・講演要旨集. 2009. 82回. 4T6a-8
Education (3)：
- 2005 - 2008 University of Shizuoka Graduate School of Nutritional and Environmental Sciences
- 2003 - 2005 Tokyo University of Science
- 1999 - 2003 Tokyo University of Science Faculty of Science and Technology Applied Biological Science
Professional career (1)：
- Ph.D. (University of Shizuoka)
Work history (2)：
- 2012/05 - 現在 Japanese Foundation for Cancer Research Cancer Chemotherapy Center
- 2008/10 - 2012/04 Mukogawa Women's University Institute for World Health Development
Awards (1)：
- 2009/10 - The Japanese Biochemical Society Excellent Presentation Award in the 82nd Annual Meeting of the Japanese Biochemical Society Identification of Gnetin C, a Resveratrol Dimer, Isolated from Indonesian Fruit Melinjo (Gnetum Gnemon L.) as a Novel and Potent Angiogenesis Inhibitor
Association Membership(s) (2)：
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