Research field (4)：
Molecular biology
, Civil engineering (environmental systems)
, Environmental effects of chemicals
, Environmental effects of radiation
Research keywords (2)：
環境毒性学
, Environmental Toxicology
Research theme for competitive and other funds (32)：
2024 - 2028 Comprehensive toxicity assessment of PFAS - Challenge to risk reduction using yeast
2022 - 2025 Basic study for safe handling of nano-sized material waste through revealing molecular mechanisms of its toxicity
2021 - 2025 Development of simple bioassay for detection of environmental trace contaminants and demonstration in Asian countries
2021 - 2025 Development of simple bioassay for detection of environmental trace contaminants and demonstration in Asian countries
2021 - 2024 Diseases caused by the accumulation of endogenous formaldehyde
2020 - 2023 Formaldehyde induces superbulky DNA interstrand crosslinks
2018 - 2023 Analysis of mechanisms of mutations from DNA damage using genome editing and site-specifically modified plasmids
2018 - 2023 Analyses of selective cytotoxicity of the anti-diabetic biguanide drug, Metformin, in solid tumor specific microenvironment
1900 - 1900 Molecular analysis of mutations induced by environmental mutagens.
環境汚染検出のためのバイオアッセイ酵母樹立
環境中化学物質による突然変異誘発の分子機構の解析
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Papers (74)：
Masanobu Kawanishi, Osamu Tsubohira, Ai Ueshima, Yuuta Hisatomi, Yoshimitsu Oda, Michio Sato, Noriyuki Miyoshi, Michihiro Mutoh, Hideki Ishikawa, Keiji Wakabayashi, et al. DNA cross-link repair deficiency enhances human cell sensitivity to colibactin-induced genotoxicity. Genes and Environment. 2025. 47. 1
Daisuke Fujiwara, Shunsuke Inaura, Yuna Tanaka, Sayoko Ito-Harashima, Asako Yamaguchi-Nomoto, Masanobu Kawanishi, Takashi Yagi, Ikuhiko Nakase, Ikuo Fujii. A Cyclized Helix-Loop-Helix Peptide as a Molecular Scaffold for Cell-Membrane Permeable Inhibitors for the Interaction Between Estrogen Receptor α and Coactivator SRC1. ChemBioChem. 2025. 26. 13
Sayoko Ito-Harashima, Erika Sano, Eiji Takada, Mayuko Nakashima, Masanobu Kawanishi, Takashi Yagi. Development of a New Reporter Gene Assay for Detecting Juvenile Hormone Agonists Using Yeast Expressing Methoprene-Tolerant of the Freshwater Cladoceran Daphnia magna. Journal of Applied Toxicology. 2025. 45. 8. 1496-1508
Masahiro Ogawa, Junya Kitamoto, Mayuko Nakashima, Yuto Hanaichi, Sayoko Ito-Harashima, Itaru Takeda, Takashi Yagi, Masanobu Kawanishi, Taku Tanaka. Intra-laboratory validation of yeast-based reporter gene assays for human thyroid hormone receptors. Journal of Pharmacological and Toxicological Methods. 2025. 132. 107593-107593
Masanobu Kawanishi, Takashi Yagi, Yukari Totsuka, Keiji Wakabayashi. DNA Repair and Mutagenesis of ADP-Ribosylated DNA by Pierisin. Toxins. 2024. 16. 8. 331-331
中村純, 藤田優也, 松田知成, 川西優喜. Metabolically activation of glycidol leads to bi-functional DNA crosslinking agent. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
KAWANISHI Masanobu. The 32nd summer school of the Research Community for Mechanisms of Mutations, Meeting report, Kawanishi Masanobu,. Genes and Environment. 2019. 41. 19
New Developments in Mutation Research
Nova Science Publishers 2007 ISBN:1594546649
Progress in Mutation Research
Nova Science Publishers (Newyork USA) 2005
ゲノム・疾患用語ハンドブック
メディカルレビュー社 2002
Education (2)：
1994 - 1998 Kyoto University Graduate School of Engineering
1990 - 1994 Kyoto University Faculty of Engineering
Professional career (1)：
(BLANK) (Kyoto University)
Work history (5)：
2022 - 現在 Osaka Metropolitan University
2000 - 2022 Osaka Pref Univ
1998 - 2000 日本学術振興会 特別研究員
1997 - Research fellow of Japan Society for the
Promotion of Science
Committee career (14)：
2018/01 - 現在 日本環境変異原学会 第一編集委員会, 委員
2014/01 - 現在 日本環境変異原学会 評議員
2013/11 - 現在 国際学術誌Frontiers in Environmental Science Reviewer Editorial Board
2013/10 - 現在 Frontiers in Environmental Science Reviewer Editorial Board
2012/01 - 現在 Genes and Environment (ISSN 1880-7046) Managing Editor
2024/01 - 2025/12 The Japanese Environmental Mutagen and Genome Society Chair of the publications committee (1st)
2012/01 - 2023/12 The Japanese Environmental Mutagen Society The Publications Committee (1st)
2010/01 - 2023/12 The Japanese Environmental Mutagen Society Public relations committee
2010/01 - 2023/12 日本環境変異原学会 広報委員
2020/01 - 2021/12 日本環境変異原学会 理事
2016/01 - 2017/12 The Japanese Environmental Mutagen Society Chair of the publications committee (1st)
2016/01 - 2017/12 日本環境変異原学会 理事
2012/01 - 2017/12 日本環境変異原学会 第一編集委員会, 編集幹事
2012/01 - 2017/12 国際学術誌Genes and Environment Managing Editor
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Awards (3)：
2016/06 - The Japanese Society of Toxicology Pfizer Awards Genotoxicity and reactive oxygen species production induced by magnetite nanoparticles in mammalian cells.
2013/11 - The Japanese Environmental Mutagen Society Achievement Award
2009/05 - The Kinki Chemical Society The Kinki Chemical Society Award for Environmental Technology
