Rchr

J-GLOBAL ID：200901071854134836 Update date: Sep. 19, 2024

Imada Katsumi

イマダカツミ | Imada Katsumi

Affiliation and department：

Research field (3)： Biophysics , Structural biochemistry , Functional biochemistry

Research keywords (4)：構造生物学 , 生物物理学 , Structure Biology , Biophysics

Research theme for competitive and other funds (35)：

2024 - 2027 還元的手法と構成的手法を組合せた蛍光蛋白質の設計原理の解析と新規蛍光蛋白質開発
2023 - 2025 固定子イオンチャネル型モーターの作動機構の解明
2021 - 2024 Structural analysis of L-amino acid oxidases with strict substrate specificity
2021 - 2024 Structural basis of the flagellar axial structure and its construction
2021 - 2023 ATP駆動型回転モーターの設計原理と機能分化

2020 - 2023 試験管内分子進化と立体構造解析に基づいた赤色蛍光タンパク質の系譜拡張

2019 - 2022 Study of the transport mechanism of periodontal pathogen's pili proteins and search for the inhibitors

2017 - 2020 Reconsitutive studies on molecular mechanisms underlying regulation of rotational molecular machines

2017 - 2020 Characterization of novel quinone containing amino acid oxidases from marine bacterium

2016 - 2019 Structural analysis of Type IX secretion system

2016 - 2019 Formation model of Bacteroidia bacteria pilus-X-ray crystal structure analysis and molecular reconstruction experiment-

2015 - 2018 Development of variable-temperature high-speed AFM and its application to temperature-dependent ATPases

2015 - 2018 細菌III型分泌の構造動態

2014 - 2017 Energy transduction mechanism of the bacterial flagellar protein export apparatus

2012 - 2017 The elucidation of the molecular mechanisms of ion selectivity of hybrid bacterial flagellar motors

2013 - 2016 Structural analysis and assembly pathway of the pathogenic bacterial type IVB secretion system transport channel

2013 - 2016 Supermolecule structure and mechanism of a novel bacterial protein secretion system, type IX secretion system

2012 - 2016 Structure and mechanism of bacterial flagella rod

2011 - 2016 Spying minority in biological phenomena -Toward bridging dynamics between individual and ensemble processes-

2014 - 2016 細胞内圧力センサーの創成を目指した、蛍光蛋白質の圧力応答機構の解明

2011 - 2016 少数分子生体システムの再構成-複合体構成分子の数の制御と理論検証-

2012 - 2015 Structural characterization of L-amino acid oxidase with high substrate specificity and industrial applications

2012 - 2015 The elucidation of origin of rotor in rotary ATPase/synthases by functional and structural analysis

2011 - 2014 Molecular disection of type IVB secretion system core complex.

2011 - 2014 細菌膜貫通センサーを介した情報伝達の構造基盤

2007 - 2012 細菌のタンパク質分泌装置と輸送基質タンパク質群の構造・機能解析

2009 - 2012 Elucidation of structure-function of unique bacterial flagellar stator complex from Bacillus spp.

2008 - 2011 細菌べん毛ロッドの形成と分子機構

2006 - 2011 回転モータートルク発生ユニットの構造基盤

2006 - 2010 Innovative nanoscience of supermolecular motor proteins working in biomembranes

2004 - 2009 Hybrid approach by electron and X-ray structural analysis for large macromolecular assemblies towards pseudo-atomic resolution

2004 - 2007 細菌べん毛軸カップリングジョイントの分子機構

2002 - 2007 体内時計蛋白質および細胞骨格と膜蛋白質の相互作用の理解に重要な分子群の構造

2006 - 2007 蛋白質結晶構造解析に基づく新たな心不全治療薬デザインのための基礎研究

2002 - 2004 Structure and fanctional analysis of NAD^+-dependent isocitrate dehydrogenase from the chemolithotroph Aci dithiobacillus thiooxidans

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Papers (129)：

Norihiro Takekawa, Tatsuro Nishikino, Jun-ichi Kishikawa, Mika Hirose, Miki Kinoshita, Seiji Kojima, Tohru Minamino, Takayuki Uchihashi, Takayuki Kato, Katsumi Imada, et al. Structural analysis of S-ring composed of FliFG fusion proteins in marine Vibrio polar flagellar motor. mBio. 2024
Miki Kinoshita, Fumiaki Makino, Tomoko Miyata, Katsumi Imada, Keiichi Namba, Tohru Minamino. Structural insights into the assembly mechanism of the flagellar MS-ring with three different symmetries. bioRxiv. 2024
Tatsuro Nishikino, Norihiro Takekawa, Jun-ichi Kishikawa, Mika Hirose, Seiji Kojima, Michio Homma, Takayuki Kato, Katsumi Imada. Structural insight into sodium ion pathway in the bacterial flagellar stator from marineVibrio. bioRxiv. 2024
Hiromi Imamura, Shiho Otsubo, Mizuho Nishida, Norihiro Takekawa, Katsumi Imada. Red fluorescent proteins engineered from green fluorescent proteins. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 45. e2307687120
Katsumi Imada, Hiroyuki Terashima. In Vitro Flagellar Type III Protein Transport Assay Using Inverted Membrane Vesicles. Methods in Molecular Biology. 2023. 17-26

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MISC (128)：

大沢陸輝, 寺原直矢, 古寺哲幸, 今田勝巳, 南野徹, 北尾彰朗. FlhAcの高速原子間力顕微鏡画像の解析. 分子シミュレーション討論会講演要旨集. 2022. 36th
佐藤啓子, 納屋昌実, 近藤好夫, 武部克希, 内藤真理子, 鈴木守, 今田勝巳, 石川岳志, 佐藤主税. 抗菌薬標的タンパク質の生化学歯周病細菌叢の病原性を抑える試み. 日本細菌学雑誌. 2021. 76. 1. 40-40
寺島浩行, 川本晃大, 巽千夏, 難波啓一, 南野徹, 本間道夫, 今田勝巳. In vitro分泌再構成系を用いたべん毛III型分泌装置の作動メカニズムの解明. 日本バイオフィルム学会学術集会プログラム・抄録集. 2020. 34回. 26-26
寺島浩行, 川本晃大, 巽千夏, 難波啓一, 南野徹, 本間道夫, 今田勝巳. 新しいアプローチで病原性細菌に挑戦する細菌III型分泌装置に対する阻害剤を探索するための新規網羅的アッセイ系. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [3S11a-01]
寺島浩行, 巽千夏, 川本晃大, 南野徹, 今田勝巳. 反転膜小胞を用いた細菌べん毛軸構造のin vitroでの構築(In vitro reconstitution of the bacterial flagellar assembly by using the inverted membrane vesicles). 日本細菌学雑誌. 2018. 73. 1. 38-38

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Books (1)：

生物物理48巻1号「細菌べん毛繊維は分子間相互作用とフラストレーションを利用して超らせん構造の変化を制御する」
日本生物物理学会 2008

Lectures and oral presentations (12)：

抗菌薬標的タンパク質の生化学歯周病細菌叢の病原性を抑える試み
(日本細菌学雑誌 2021)
3K0945 Molecular Dynamics Simulation of Flagellin
(Seibutsu Butsuri 2002)
2C1330 Analysis of heat-stable conformational memory in COOH-terminal region of flagellin
(Seibutsu Butsuri 2002)
2C1445 Atomic structure of FlgE-32k, a majore fragment of the hook protein
(Seibutsu Butsuri 2002)
3H1500 Structure analysis of bacterial flagellar filament by X-ray fiber diffraction
(Seibutsu Butsuri 2002)

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Works (3)：

生体超分子ナノマシンの構造解析
2002 - 2007
Dynamic Nanomachine Project
2002 - 2007
超分子擬似原子分解能電子線・X線構造解析法
2004 -

Education (3)：

1989 - 1992 Osaka university Graduate School of Science Department of Macromolecular Science
1987 - 1989 Osaka University Graduate School of Science Department of Macromolecular Science
1983 - 1987 Osaka University School of Science Macromolecular Science

Professional career (1)：

Ph.D (Osaka University)

Work history (7)：

2010/10 - 現在 Osaka University Department of Macromolecular science, Graduate school of science Professor
2007/04 - 2010/09 Osaka University Graduate school of Frontier Biosciences Associate Professor
2004/12 - 2008/03 JST Dynamic nanomachine project, ICORP Group Leader
2002/04 - 2007/03 Osaka University Department of Frontier Biosciences Associate professor
1997/10 - 2002/03 JST Protonic NanoMachine Project, ERATO Group Leader

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Awards (4)：

2009 - 第9回日本蛋白質科学会年会ポスター賞
2008 - Best Poster from Students at the XXI Congress of the International Union of Crystallography
2008 - Best Poster from Students at the XXI Congress of the International Union of Crystallography
2006 - ひょうごSPring-8賞

Association Membership(s) (6)：

The American Society for Microbiology , 日本蛋白質科学会 , 日本生化学会 , 日本生物物理学会 , The Japanese Biochemical Society , Biophysical Society of Japan

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