Rchr
J-GLOBAL ID:200901071878902567   Update date: Nov. 28, 2025

Tanaka Toshihide

タナカ トシヒデ | Tanaka Toshihide
Affiliation and department:
Job title: Professor
Research field  (5): Immunology ,  Cell biology ,  Tumor biology ,  Neurosurgery ,  Experimental pathology
Research keywords  (5): 低浸襲な画像ガイド下脳神経外科手術と脳腫瘍手術に対する術中MRI ,  樹状細胞を基調とした脳腫瘍に対する免疫治療 ,  脳虚血と血管生物学 ,  脳腫瘍に対する遺伝子治療 ,  脳腫瘍病理と血管新生
Research theme for competitive and other funds  (15):
  • 2025 - 2029 Identification of durational factors for therapeutic efficacy of bevacizumab focused on tumor microenvironment in glioblastoma
  • 2025 - 2026 免疫治療をした肺癌と脳転移同時発症例における原発巣・脳転移巣の腫瘍微小環境の比較
  • 2024 - 2025 悪性脳腫瘍に対する樹状細胞免疫治療と抗VEGF抗体併用療法における腫瘍微小環境の探索的研究
  • 2021 - 2025 Investigation of the effect and prediction factors of bevacizumab on immunoregulation in glioblastoma
  • 2023 - 2024 悪性神経膠腫に対するベバシズマブ術前化学療法の探索的研究:第二相臨床試験および病理組織学的解析
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Papers (169):
  • Kyoichi Tomoto, Akihiko Teshigawara, Tomohiro Aoki, Masahiko Itani, Yuzuru Hasegawa, Yuichi Murayama, Toshihide Tanaka. Exploratory analyses of factors related to 5-aminolevulinic acid-induced intraoperative hypotension during malignant glioma surgery via literature review. Photodiagnosis and Photodynamic Therapy. 2025
  • Yohei Yamamoto, Tomona Maetani, Hiroki Narita, Yurika Terasawa, Naoki Kato, Yasuharu Akasaki, Yuichi Murayama, Toshihide Tanaka. Alteration of Prognostic Factors for Patients with Brain Metastases from Lung Cancer Before and After the Introduction of Immune Checkpoint Inhibitors: A Retrospective Single-Institution Study. Cancers. 2025. 17. 3067-3067
  • Rintaro Tachi, Michiyasu Fuga, Toshihiro Ishibashi, Kazufumi Horiuchi, Akihiko Teshigawara, Ken Aoki, Issei Kan, Toshihide Tanaka, Yuichi Murayama. Efficacy and Safety of the Neuroform Atlas Stent for Bifurcation Type Unruptured Cerebral Aneurysms: Comparison of Single versus Y Stents with Propensity Score Matching. Journal of Neuroradiology. 2025. 101369-101369
  • Tumor-to-tumor metastasis in a patient with hemangioblastoma unrelated to von-Hippel-Lindau disease: A case report and review of literature. 2025. 7. 6
  • Clinical benefit of first-line bevacizumab for eldery patients with unresectable glioblastoma and poor performance status. Jikeikai Medical Journal. 2025. 72. 25-32
more...
MISC (171):
  • Suzuki Y., Riviere-Cazaux C., Warrington AE, Tanaka T., Sekiguchi K., Yoshitake M., Burns TC. Can the tumor microenvironment attenuate drug efficacy? Potential vulnerabilities of LAT1 inhibitors. Neuro Oncology. 2025. 27. suppl 5
  • Taketo Ezaki, Toshihide Tanaka, Ryota Tamura, Yohei Yamamoto, Jun Takei, Yasuharu Akasaki, Masahiro Toda, Yuichi Murayama, Keisuke Miyake, Hikaru Sasaki. INTEGRATIVE PAIRED ANALYSIS OF BEVACIZUMAB RESISTANCE USING GENE PROFILES AND IMAGING FEATURES IN TREATMENT FOR NEWLY DIAGNOSED GLIOBLASTOMA. Neuro Oncology. 2025. 27. suppl 5
  • Comparative analyses of immunological tumor microenvironment in paired samples from primary lung cacner and brain metastases. Brain Tumor Pathology. 2025. 42. 102
  • Multi-omics analyses of immunological;umor microenvironmen;in paired samples from newly diagnosed;recurrent glioblsatomas before;after bevacizumab therpay. Brain Tumor Pathology. 2025. 42. 92
  • Toshihide Tanaka. Translational approach for brain tumors. 2025. 38-38
more...
Books (13):
  • 脳腫瘍の化学療法, (3) Bevacizumab.
    日本臨床社(東京) 2023
  • 神経膠芽腫における腫瘍微小環境に関連したvascular endothelial growth factor (VEGF)による腫瘍血管新生と腫瘍免疫の調節
    実験医学・用土社 2019
  • Surgical wound management following craniotomy with attention to bevacizumab therapy
    2019 ISBN:9781536153354
  • Development and Perspectives of Histopathological Findings of Glioblastoma Treated by Bevacizumab
    2019 ISBN:9781536153354
  • 「わたしの手術記載」:若年性脳動静脈奇形(左前頭葉)
    (株)メジカルビュー社 2018
more...
Lectures and oral presentations  (387):
  • 術前ベバシズマブ投与後における膠芽腫摘出術の効用と課題
    (第34回日本脳神経外科CNTT学会 2025)
  • 急速に全身へ転移したGlioblastomaでの剖検例
    (第43回日本脳腫瘍学会学術総会 2025)
  • 後期高齢者における転移性脳腫瘍の予後因子に関する検討
    (第43回日本脳腫瘍学会学術総会 2025)
  • 小脳血管芽腫に乳癌転移を来したTumor-to-Tumor Metastasisの一例
    (第43回日本脳腫瘍学会学術総会 2025)
  • 多発髄膜腫に酷似した神経サルコイドーシスの1例
    (第43回日本脳腫瘍学会学術総会 2025)
more...
Works (2):
  • 日本分子脳神経外科学会、ジュニア世話人
    2004 -
  • Improved method of protein delivery, composition and thereof -us patient
    1998 -
Education (2):
  • 1993 - 1997 Jikei University Graduate School, Division of Medicine
  • 1985 - 1991 Jikei University Faculty of Medicine
Professional career (1):
  • (BLANK) (Jikei University)
Work history (7):
  • 2025/08 - 現在 The Jikei University School of Medicine Department of Neurosurgery Professor
  • 2021/11 - 2025/07 The Jikei University School of Medicine Department of Neurosurgery Associate Professor
  • 2009/09 - 2021/10 The Jikei University School of Medicine Department of Neurosurgery
  • 1997/04 - 2009/08 Jikei University School of Medicine Department of Neurosurgery Instructor
  • 1994/01 - 1997/03 Harvard Medical School Dana-Farber Cancer Institute Research Associate
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Committee career (11):
  • 2025/01 - 現在 東京脳腫瘍研究会 世話人
  • 2024/11 - 現在 がんワクチン療法研究会 運営委員
  • 2024 - 現在 日本メディカルイラストレーション学会 理事
  • 2023 - 現在 神奈川脳神経外科手術手技研究会 世話人
  • 2020 - 現在 Cellm001による初発膠芽腫治療効果無作為比較対照試験 画像中央判定委員
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Awards (4):
  • 2022/12 - Japan Society for Neuro-Oncology Top Scoring Abstract award A prospective multicenter phase I/IIa study of prospective neoadjuvant bevacizumab for newly diagnosed glioblastoma
  • 1998/01 - アメリカ癌学会関連"血管新生と癌"Young Investigator Travel Awardee
  • 1997/09 - Shonan Neurosurgery English Forum Sammy's Award
  • 1997/04 - アメリカ癌学会 Young Investigator Award
Association Membership(s) (12):
日本CI学会 ,  日本神経外傷学会 ,  日本癌学会 ,  Asian Conference of Neurological Surgeon ,  New York Academy of Science ,  日本血管細胞生物学学会 ,  日本遺伝子治療学会 ,  アメリカ癌学会 ,  日本脳神経外科学会 ,  日本脳腫瘍の外科学会 ,  日本メディカルイラストレーション学会 ,  Japan Society for Neuro-Oncology
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