Wada Jun

ワダジュン | Wada Jun

Affiliation and department：
Job title： Professor

Research field (2)： Metabolism and endocrinology , Nephrology

Research keywords (4)：腎臓病学 , 糖尿病 , Nephrology , Diabetes Mellitus

Research theme for competitive and other funds (28)：

2020 - 2023 尿レクチンアレイ解析を用いた腎疾患診断キットの開発
2019 - 2022 Significance of glycan abnormalities in diabetic nephropathy
2016 - 2019 Pathological involvement of RAGE/HMGB1 Axis in systemic lupus erythematosus
2017 - 尿中糖鎖プロファイリングによるIgA腎症の診断法の開発
2014 - 2017 Vaspin and its interacting molecules as therapeutic targets for metabolic syndrome

2014 - 2017 The role of vaspin in metabolic syndrome associated renal disease

2014 - 2017 The impact of ACAM/CLMP on the adipocytes differentiation and obesity through the primary ciliary machinery

2013 - 2015 脂肪蓄積を制御する膜タンパク質と可溶性分泌型のアディポサイトカインとしての意義

2012 - 2015 糖尿病性腎症の糖鎖プロファイリングによる新規バイオマーカーの同定

2011 - 2014 The significance of vaspin in metabolic syndrome and drug discovery

2011 - 2013 脂肪蓄積を制御する膜蛋白同定とその可溶性分泌型のアディポサイトカインとしての意義

2011 - 2012 Pathogenesis ofmetabolic syndrome and non-alcoholic steatohepatitis

2009 - 2012 Nuclear receptors as therapeutic targets for diabeticnephropathy.

2008 - 2010 The role of vaspin in metabolic syndrome

2007 - 2008 Exploratory research to development of novel therapeutic strategy for diabetic nephropathy

2007 - 2008 Global survey on clinical research supporting and promoting system, aiming Japanese clinical research improvement.

2006 - 2008 New therapeutic approach to diabetic nephropathy by modulating mitochondrial function

2005 - 2007 Identification of Interacting Molecules with Collectrin and their roles in Hypertension

2005 - 2006 Novel therapeutic targets for diabetic nephropathy.

2003 - 2004 Role of Macrophage in the pathogenesis of diabetic nephropathy and novel therapeutic target.

2002 - 2004 Reactive oxygen species and diabetic nephropathy

2002 - 2004 Identification of Novel ACE2 homologue, collectrin, and its role in renal organogenesis and progressive renal failure.

2002 - 2003 Study on the mechanism for the production of CXCR3-agonisitic chemokines by synovial fibroblasts from patients with rheumatoid arthritis

2001 - 2002 Role of Macrophage in the pathogenesis of diabetic nephropathy revealed by ICAM-1 deficient mice.

2000 - 2001 Study on the mechanism for establishment of the Thl-type immune response in rheumatoid arthritis

1999 - 2001 Molecular mechanism of glomerular hyperfiltration in diabetic nephropathy revealed by gene expression profiling.

1999 - 2000 Application of anti-adhesion molecule therapy for glomerulonephritis -Effects of sulfated oligosaccharides as selectin-blocking agents-

1998 - 1999 新しく発見された動物レクチンGalectin-9の研究

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Papers (503)：

Atsuko Nakatsuka, Satoshi Yamaguchi, Jun Wada. GRP78 Contributes to the Beneficial Effects of SGLT2 Inhibitor on Proximal Tubular Cells in DKD. Diabetes. 2024
Hiroaki Iijima, Maki Gouda, Hideaki Hida, Kazumi Mori-Anai, Akiko Takahashi, Ryoichi Minai, Hideki Ninomiya, Yoshiyuki Saito, Atsushi Miyawaki, Jun Wada. Renal outcomes with sodium-glucose cotransporter 2 inhibitors in Japanese people with grade 3 chronic kidney disease and type 2 diabetes: Analysis of medical administrative databases. Diabetes, Obesity and Metabolism. 2024
Soichiro Haraguchi, Kenji Tsuji, Hiroyuki Nakanoh, Kazuhiko Fukushima, Shinji Kitamura, Jun Wada. Effects of HIF-PHD inhibitors in kidney development. Nephrology Dialysis Transplantation. 2024
Yuzuki Kano, Satoshi Yamaguchi, Koki Mise, Chieko Kawakita, Yasuhiro Onishi, Naoko Kurooka, Ryosuke Sugawara, Haya Hamed Hassan Albuayjan, Atsuko Nakatsuka, Jun Eguchi, et al. Inhibition of Amino Acids Influx into Proximal Tubular Cells Improves Lysosome Function in Diabetes. Kidney360. 2023
Kenji Tsuji, Hiroyuki Nakanoh, Kensaku Takahashi, Takafumi Morita, Yizhen Sang, Kazuhiko Fukushima, Natsumi Matsuoka-Uchiyama, Yasuhiro Onishi, Haruhito A Uchida, Shinji Kitamura, et al. Kidney Veno-Muscular Characteristics and Kidney Disease Progression: A Native Kidney-Biopsy Study. Kidney medicine. 2023. 5. 12. 100733-100733

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MISC (207)：

江口潤, 和田淳. 【指定難病Up to Date】家族性低βリポタンパク血症に関する最近の知見. 岡山医学会雑誌. 2023. 135. 2. 81-84
和田淳, 中司敦子. 糖尿病性腎症研究の最新知見近位尿細管細胞のオルガネラ機能不全とバスピンによる腎保護作用. 糖尿病合併症. 2023. 37. 2. 227-231
大西康博, 和田淳. 【糖尿病性腎臓病・腎硬化症の病態と診療】糖尿病性腎臓病・腎硬化症のバイオマーカー. 月刊糖尿病. 2023. 15. 4. 56-62
辻憲二, 福島和彦, 喜多村真治, 和田淳. 【SGLT2阻害薬から見えてくる新たな生体システムの姿】SGLT2阻害剤のオートファジー制御による臓器保護作用. 細胞. 2023. 55. 4. 205-208
和田嵩平, 和田淳. 【チームでかかわる糖尿病性腎症重症化予防】ダウンロードできる!患者の腎臓を守るための説明シート腎症になったら、食事はどう変わるの?. 糖尿病ケア+. 2023. 20. 2. 264-265

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Patents (6)：

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Books (4)：

Chapter 3 Prominent insulin resistance in congenital generalized lipoatrophy, Ed Oohashi T, Tsukahara H, Ramirez F, Barber CL, Otsuka F, In Human Pahtobiochemistry
Springer Nature Singapore 2019
Chapter 12 Vaspin: Visceral Adipose Tissue-Derived Serpin with Insulin-Sensitizing Effects, Ed Bojidor Georgiev and Sava Markovski, In Serpins and Protein Kinase Inhibitors: Novel Functions, Structural Features and Molecular Mechanisms
Nova Science Publishers, Hauppauge NY 2009
Chapter 11 Protein sequence analysis, pp333-378, Ed Shui Qing Ye, In Bioinformatics, A practical Approach
Chapman & Hall/CRC 2008
Chapter 18 Serpins and the metabolic syndrome, pp411-423, Ed Gary A. Silverman and David A. Lomas, In Molecular and cellular aspects of the serpinopathies and disorders in serpin activity
World Scientific Publishing, Singapore 2007

Education (2)：

- 1992 Okayama University
- 1988 Okayama University Medical School

Professional career (1)：

医学博士

Work history (4)：

2015/08 - 現在 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences
2010/01 - 2015/07 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences
2006/08 - 2008/07 文部科学省研究振興局学術調査官
1992/10 - 1996/11 Northwestern University Medical School Department of Pathology Research Associate

Committee career (12)：

2023/05 - 現在日本腎臓リハビリテーション学会理事
2021/10 - 現在日本肥満学会理事
2020/04 - 現在日本腎臓学会理事
2017/10 - 現在日本糖尿病合併症学会評議員
2017/06 - 現在日本動脈硬化学会評議員

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Awards (5)：

2012/11 - 岡山市文化奨励賞
2009 - 日本肥満学会学術奨励賞
2002 - 糖尿病合併症学会Young Investigator Award
2001 - 岡山医師会奨励賞
2001 - 岡山医学賞結城賞

Association Membership(s) (13)：

American College of Physicians , American Society of Nephrology , American Diabetes Association , 日本糖尿病肥満動物学会 , 日本内分泌学会 , 日本リウマチ学会 , 日本病態栄養学会 , 日本透析医学会 , 日本動脈硬化学会 , 日本肥満学会 , 日本腎臓学会 , 日本糖尿病学会 , 日本内科学会

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