Rchr
J-GLOBAL ID:200901072254016208   Update date: Jun. 06, 2019

KUME Akihiro

クメ アキヒロ | KUME Akihiro
Affiliation and department:
Job title: Professor
Research field  (4): Molecular biology ,  Cell biology ,  Hematology ,  Pediatrics
Research keywords  (2): Regulatory Science ,  Gene Therapy
Research theme for competitive and other funds  (3):
  • 1994 - 2023 Proliferation and Differentiation of Hemutopoietic Stem cells
  • 1996 - 2023 Development of New Vectors for Gene Therapy
  • Department of Gene Therapy Vectors
Papers (22):
  • KUME Akihiro. Complete restoration of phenylalanine oxidation in phenylketonuria mouse by a self-complementary adeno-associated virus vector. Journal of Gene Medicine. 2011. 13. 2. 114-122
  • Kurosaki F, Uchibori R, Sehara Y, Saga Y, Urabe M, Mizukami H, Hagiwara K, Kume A. AAV6-Mediated IL-10 Expression in the Lung Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice. Human gene therapy. 2018. 29. 11. 1242-1251
  • Sato N, Saga Y, Uchibori R, Tsukahara T, Urabe M, Kume A, Fujiwara H, Suzuki M, Ozawa K, Mizukami H. Eradication of cervical cancer in vivo by an AAV vector that encodes shRNA targeting human papillomavirus type 16 E6/E7. International journal of oncology. 2018. 52. 3. 687-696
  • Uehara T, Kanazawa T, Mizukami H, Uchibori R, Tsukahara T, Urabe M, Kume A, Misawa K, Carey TE, Suzuki M, Ichimura K, Ozawa K. Novel anti-tumor mechanism of galanin receptor type 2 in head and neck squamous cell carcinoma cells. Cancer science. 2014. 105. 1. 72-80
  • Takahashi K, Mizukami H, Saga Y, Takei Y, Urabe M, Kume A, Machida S, Fujiwara H, Suzuki M, Ozawa K. Suppression of lymph node and lung metastases of endometrial cancer by muscle-mediated expression of soluble vascular endothelial growth factor receptor-3. Cancer science. 2013. 104. 8. 1107-1111
more...
MISC (27):
Books (1):
  • CD34 Workshop : Cross - linking of CD34 on hematopoietic cells induces homotypic cell adhesion via clustering of CD34 and mobilization of adhesion molecules. (共著)
    Lenkocyte Typing VI , Garland Puhilishing Inc . , New York and London 1997
Works (1):
  • Selevtive Expansion of Gene Tically Modified Hemutopoietic stom cells
    1999 - 2000
Education (1):
  • - 1990 Tohoku University Graduate School, Division of Medicine
Professional career (1):
  • (BLANK)
Work history (6):
  • 1992 - 1994 Indiana University, Post-doctoral Fellow
  • 1994 - 1996 Kumamoto University, Research Assistant
  • 1996 - 2000 Jichi medical School, Lecturer
  • 2014 - 2016 PMDA Principal Reviewer
  • 2001 - Jichi medical School, Assistant Professor
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