Yamashita Kyoko

ヤマシタキョウコ | Yamashita Kyoko

Affiliation and department：

Research field (1)： Oral medicine

Research keywords (5)：マトリックス , 阻害 , 増殖 , 細胞 , 生化学

Research theme for competitive and other funds (16)：

2007 - 2009 An in vitro model of cartilage degradation by chondrocytes in a three-dimensional culture system
2002 - 2003 Concentration-dependent switch-on and -off mechanism of cell-growth promoting activity of TIMP-1
1999 - 2001 有系分裂中の細胞内におけるTIMP-1の役割
1997 - 1999 Cell growth-promoting activity of TIMPs - Mechanism of signal transduction in human osteoblast-like cells
1996 - 1997 Cell cycle-associated accumulation of TIMP-1 in the nuclei of human gingival fibroblasts

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Papers (8)：

XK Guo, WQ Zhao, C Kondo, N Shimojo, K Yamashita, T Aoki, T Hayakawa. Tissue inhibitors of metalloproteinases-1 (TIMP-1) and-2(TIMP-2) are major serum factors that stimulate the TIMP-1 gene in human gingival fibroblasts. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 2006. 1763. 3. 296-304
T Kuboki, M Kanyama, T Nakanishi, K Akiyama, K Nawachi, H Yatani, K Yamashita, T Takano-Yamamoto, M Takigawa. Cbfa1/Runx2 gene expression in articular chondrocytes of the mice temporomandibular and knee joints in vivo. ARCHIVES OF ORAL BIOLOGY. 2003. 48. 7. 519-525
Nakata Kazuhiko, Sato Yoshitaka, Iwata Takahiro, Yoshida Tsutomu, Suzuki Kazuyoshi, Yamasaki Masahiro, Nakamura Hiroshi, Yamashita Kyoko, Fujimoto Noboru, Hayakawa Taro. Production of Matrix Metalloproteinases (MMPs) and Their Inhibitors (TIMPs) by Human Periodontal Ligament Cells : Effects of Sonicated Bacterial Extracts from Anaerobic Gram-negative Bacteria. Journal of the Japanese Association of Periodontology. 1997. 39. 2. 205-216
K. Iwata, K. Yamashita, S. Kodama, H. Iwata, T. Hayakawa. Significance of tissue inhibitor of metalloproteinases (TIMP) in synovial fluid of rheumatoid arthritis. Matrix (Stuttgart, Germany). Supplement. 1992. 1. 332-333
Y OKADA, Y GONOJI, K NAKA, K TOMITA, NAKANISHI, I, K IWATA, K YAMASHITA, T HAYAKAWA. MATRIX METALLOPROTEINASE-9 (92-KDA GELATINASE TYPE-IV COLLAGENASE) FROM HT-1080 HUMAN FIBROSARCOMA CELLS - PURIFICATION AND ACTIVATION OF THE PRECURSOR AND ENZYMATIC-PROPERTIES. JOURNAL OF BIOLOGICAL CHEMISTRY. 1992. 267. 30. 21712-21719

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MISC (33)：

K Nishimura, K Yamashita, Y Kato, T Iwata, K Iwata, T Nishikawa, S Goto, T Hayakawa. Inhibitory activity on matrix metalloproteinases and cell-proliferating activity of tissue inhibitor of metalloproteinases-1 (TIMP-1) - contrastive difference between human and bovine TIMP-1s on mouse cell proliferation. GROWTH FACTORS. 2005. 23. 2. 135-142
T Wang, K Yamashita, K Iwata, T Hayakawa. Both tissue inhibitors of metalloproteinases-1 (TIMP-1) and TIMP-2 activate Ras but through different pathways. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002. 296. 1. 201-205
T Fukunaga, T Yamashiro, K Yamashita, JN Pereira, M Takigawa, T Takano-Yamamoto. Expression of CTGF in endochondral and intramembranous ossification during mandibular fracture healing. JOURNAL OF DENTAL RESEARCH. 2002. 81. A190-A190
T Sobue, Y Hakeda, Y Kobayashi, H Hayakawa, K Yamashita, T Aoki, M Kumegawa, T Noguchi, T Hayakawa. Tissue inhibitor of metalloproteinases 1 and 2 directly stimulate the bone-resorbing activity of isolated mature osteoclasts. JOURNAL OF BONE AND MINERAL RESEARCH. 2001. 16. 12. 2205-2214
新らしく開発されたチタン合金とヒト歯肉線維芽細胞の親和性について. 歯科基礎医学会雑誌. 2000. 42. 5. 429

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Books (3)：

Methods in Mollecular Biology 151-Matrix Metalloproteinases Protocols-
Humana Press 2001
細胞外マトリックス研究法(基礎知識からデータの解釈まで)
コラーゲン技術研修会 1998
The Protocols for Extracellular Matrix.
1998

Association Membership(s) (3)：

日本歯科基礎医学会 , 日本歯周病学会 , 日本生化学会

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