Rchr
J-GLOBAL ID:200901072415856368   Update date: Dec. 06, 2023

Ishii Yukio

イシイ ユキオ | Ishii Yukio
Affiliation and department:
Job title: Professor
Research field  (3): Infectious disease ,  Allergies and connective tissue disease ,  Respiratory medicine
Research theme for competitive and other funds  (22):
  • 2018 - 2021 肺の抗酸化修飾による老化制御の試みとアンチエイジングへの応用
  • 2009 - 2012 肺癌の抗癌剤耐性に及ぼす喫煙の影響に関する分子メカニズムの解明
  • 2009 - 2011 Nrf2 is a novel molecular target for treatment of steroid-resistant inflammatory lung diseases.
  • 2009 - 2010 Nrf2システムを利用した抗癌剤感受性診断法の開発と臨床応用
  • 2007 - 2010 ディーゼル排気が気管支喘息に及ぼす影響の試験法の調査
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Papers (105):
  • Sherpa, Mingma Thsering, Kiwamoto, Takumi, Matsuyama, Masashi, Tsunoda, Yoshiya, Yazaki, Kai, Yoshida, Kazufumi, Nakajima, Masayuki, Matsuno, Yosuke, Morishima, Yuko, Ishii, Yukio, et al. Has2 Regulates the Development of Ovalbumin-Induced Airway Remodeling and Steroid Insensitivity in Mice. Frontiers in immunology. 2022. 12
  • Yazaki, Kai, Matsuno, Yosuke, Yoshida, Kazufumi, Sherpa, Mingma, Nakajima, Masayuki, Matsuyama, Masashi, Kiwamoto, Takumi, Morishima, Yuko, Ishii, Yukio, Hizawa, Nobuyuki. ROS-Nrf2 pathway mediates the development of TGF-β1-induced epithelial-mesenchymal transition through the activation of Notch signaling. European journal of cell biology. 2021. 100. 7-8. 151181-151181
  • Nakajima, Masayuki, Matsuyama, Masashi, Kawaguchi, Mio, Matsumura, Sosuke, Kiwamoto, Takumi, Matsuno, Yosuke, Morishima, Yuko, Yoshida, Kazufumi, Sherpa, Mingma Thsering, Yazaki, Kai, et al. Depletion of PD-1 or PD-L1 did not affect the mortality of mice infected with Mycobacterium avium. Scientific reports. 2021. 11. 1
  • Tsunoda, Yoshiya, Sherpa, Mingma Thsering, Kiwamoto, Takumi, Matsuyama, Masashi, Osawa, Hajime, Sakurai, Hirofumi, Hayashi, Shigen, Matsuno, Yosuke, Morishima, Yuko, Ishii, Yukio, et al. Has2 deficiency enhances OVA-induced airway inflammation and hyperresponsiveness in mice. Allergy. 2021. 76. 7. 2214-2218
  • Nakajima, Masayuki, Matsuyama, Masashi, Kawaguchi, Mio, Kiwamoto, Takumi, Matsuno, Yosuke, Morishima, Yuko, Yoshida, Kazufumi, Sherpa, Mingma, Yazaki, Kai, Osawa, Hajime, et al. Nrf2 Regulates Granuloma Formation and Macrophage Activation during Mycobacterium avium Infection via Mediating Nramp1 and HO-1 Expressions. mBio. 2021. 12. 1
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Patents (2):
  • M-CSFを用いた続発性肺胞蛋白症の治療
  • 抗酸化ストレス酵素発現誘導剤およびNrf活性化剤
Books (16):
  • 内科学
    朝倉書店 2017 ISBN:9784254322705
  • 第一線呼吸器科医が困った症例から学んだ教訓
    2017 ISBN:9784771904767
  • 呼吸器疾患と転写因子
    呼吸と循環・医学書院 2008
  • 転写因子Nrf2(NF-E2 related factor-2)をめぐって
    Annual Review 2008呼吸器 2008
  • 特発性肺線維症の発症機序
    Medical Practice 2007
more...
Lectures and oral presentations  (40):
  • The Role of Mitochondria-Dependent Metabolic Reprogramming in the Pathogenesis of Pulmonary Fibrosis
    (APSR 2021 2021)
  • EGFR-TKI が奏功した EGFR 遺伝子変異陽性肺扁平上皮癌の1例
    (第243回日本呼吸器学会関東地方会 2021)
  • Role of Nrf2 in Pulmonary MAC Infection Using Mice Model
    (International Conference of the American-Thoracic-Society (ATS) 2020)
  • Hyaluronan Synthase 2 (HAS2) Mediates Elastase-Induced Airway Inflammation and Emphysema in Mice
    (International Conference of the American-Thoracic-Society (ATS) 2020)
  • マウスを用いた肺MAC感染モデルにおけるNrf2の役割
    (第60回日本呼吸器学会学術講演会 2020)
more...
Education (2):
  • - 1990 University of Tsukuba Graduate School, Division of Medicine
  • - 1986 University of Tsukuba School of Medicine
Work history (3):
  • 2012/04/01 - 現在 University of Tsukuba Professor
  • 2009/09/01 - 現在 University of Tsukuba Comprehensive Human Sciences Associate Professor
  • 2000/04/01 - 現在 University of Tsukuba Institute of Clinical Medicine Assistant professor
Committee career (4):
  • 2019/04 - 現在 日本呼吸器学会 英文編集委員会委員
  • 2019/04 - 現在 日本結核病学会 編集委員会委員
  • 2019/04 - 現在 日本結核病学会 ガイドライン作成委員
  • 2018/07 - 2020/06 学術振興会 特別研究員等審査会専門委員および国際事業委員会書面審査員
Awards (5):
  • 2014/07/01 - 公益財団法人日本アレルギー協会真鍋奨学助成
  • 2012/04/19 - Kumagai Award of the Japanese Respiratory Society
  • 2010/08/28 - 岡本敏記念肺線維症研究助成
  • 2009/09/01 - AstraZenaca AstraZeneca Research Grant
  • 2006/12/02 - 第15回Pneumo Forum賞
Association Membership(s) (9):
American Thoracic Society ,  American Society for Microbiology ,  European Respiratory Society ,  Japanese Society of Medical Oncology (JSMO) ,  Japanese Society of Medicine ,  THE JAPANESE RESPIRATORY SOCIETY ,  JAPANESE SOCIETY FOR TUBERCULOSIS ,  The Japanese Association for Infectious Diseases ,  JAPANESE SOCIETY OF ALLERGOLOGY
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