Rchr
J-GLOBAL ID:200901072497604647   Update date: Apr. 07, 2021

Kawai Hidehiko

カワイ ヒデヒコ | Kawai Hidehiko
Affiliation and department:
Research field  (2): Environmental effects of chemicals ,  Environmental effects of radiation
Research keywords  (2): Carcinogenesis ,  radiobiology
Papers (57):
  • Ueda, Masanobu, Matsuura, Kenkyo, Kawai, Hidehiko, Wakasugi, Mitsuo, Matsunaga, Tsukasa. Spironolactone-induced XPB degradation depends on CDK7 kinase and SCFFBXL18 E3 ligase. GENES TO CELLS. 2019. 24. 4. 284-296
  • Yuji Masuda, Rie Kanao, Hidehiko Kawai, Iwao Kukimoto, Chikahide Masutani. Preferential digestion of PCNA-ubiquitin and p53-ubiquitin linkages by USP7 to remove polyubiquitin chains from substrates. The Journal of biological chemistry. 2019. 294. 11. 4177-4187
  • Shimura, Tsutomu, Sasatani, Megumi, Kawai, Hidehiko, Kamiya, Kenji, Kobayashi, Junya, Komatsu, Kenshi, Kunugita, Naoki. Radiation-Induced Myofibroblasts Promote Tumor Growth via Mitochondrial ROS-Activated TGF beta Signaling. MOLECULAR CANCER RESEARCH. 2018. 16. 11. 1676-1686
  • Yusuke Okamoto, Watal M. Iwasaki, Kazuto Kugou, Kazuki K. Takahashi, Arisa Oda, Koichi Sato, Wataru Kobayashi, Hidehiko Kawai, Ryo Sakasai, Akifumi Takaori-Kondo, et al. Replication stress induces accumulation of FANCD2 at central region of large fragile genes. NUCLEIC ACIDS RESEARCH. 2018. 46. 6. 2932-2944
  • Tsutomu Shimura, Megumi Sasatani, Hidehiko Kawai, Kenji Kamiya, Junya Kobayashi, Kenshi Komatsu, Naoki Kunugita. ATM-mediated mitochondrial damage response triggered by nuclear DNA damage in normal human lung fibroblasts. Cell Cycle. 2017. 16. 24. 2345-2354
more...
Lectures and oral presentations  (19):
  • γ線照射環境下での線量率依存的な細胞運命決定とその分子機構の解析
    (第55回原子爆弾後障害研究会 2015)
  • Dose rate-dependent cellular senescence in response to chronic -irradiation via the ATM/TP53/p21 pathway.
    (The 5th International Symposium of RIRBM 2015)
  • Perturbation of AKT/cyclin D1 signaling pathway by oxidative stresses following low dose long-term fractionated radiation in normal human fibroblasts.
    (The 5th International Symposium of RIRBM 2015)
  • DNA Damage Response in Human Induced Pluripotent Stem Cells.
    (The 5th International Symposium of RIRBM 2015)
  • Effects of low dose gamma irradiation on primary human endothelial cells
    (The 5th International Symposium of RIRBM 2015)
more...
Education (3):
  • 1997 - 2000 Hiroshima University Graduate School, Division of Medical Sciences
  • 1995 - 1997 Kanazawa University Graduate School, Division of Pharmaceutical Sciences
  • 1991 - 1995 Kanazawa University Faculty of Pharmaceutical Science
Professional career (2):
  • Doctor of Philosophy in Medical Science (Hiroshima University)
  • Master of Pharmaceutical Science (Kanazawa University)
Work history (6):
  • 2017/09/01 - 2019/03/31 Hiroshima University Graduate School of Biomedical & Health Sciences (School of Pharmaceutical Sciences) Associate Professor
  • 2017/09/01 - 2019/03/31 Hiroshima University Graduate School of Biomedical & Health Sciences (School of Pharmaceutical Sciences) Associate Professor
  • 2007/04/01 - 2017/08/31 Hiroshima University Research Institute for Radiation Biology and Medicine Assistant Professor
  • 2003/11/01 - 2007/03/31 Hiroshima University Research Institute for Radiation Biology and Medicine Research Assistant
  • 2003/01/01 - 2003/10/31 Harvard University Research Associate
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Awards (5):
  • 2015/05 - ICRR2015 Excellent Poster Award The function of Chromatin Remodeling Complexes in Cell-fate Decision in Response to Chronic Ionizing Irradiation
  • 2015/05 - ICRR2015 Excellent Poster Award Enhanced DNA End Resection and Subsequent Responses During The Processing of Complex DNA Double Strand Breaks Induced By Heavy Ion Beams
  • 2015/05 - ICRR 2015 Excellent Poster Award An Integrated Approach Using High-throughput Sequencing and Imaging Technologies to the Study of Cellular Responses to Low Dose Radiation
  • 2012/09/07 - 日本放射線影響学会 日本放射線影響学会奨励賞
  • 2011/01/22 - 日本遺伝学会 日本遺伝学会第82回大会Best Papers賞
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