Research theme for competitive and other funds (11):
2024 - 2025 キラルアレンの汎用的な絶対立体配置決定法の開発
2023 - 2024 キラルアレンの汎用的な絶対立体配置決定法の開発
2022 - 2023 キラルアレンの汎用的な絶対立体配置決定法の開発
2016 - 2018 Redefinition of fluorescence-detected circular dichroism for a practical stereo-structure analysis
2015 - 2018 An attempt to develop novel CaM kinase phosphatase inhibitors that are effective for suppression of cancer metastasis with low cytotoxicity
2013 - 2015 Study toward a practical method for protein structure analysis using an artifact-free fluorescence-detected circular dichroism
2010 - 2012 Method for Pin-Point Structure Analysis of Proteins by Fluorescence-Detected CD
2009 - 2011 Mechanisms for switching off of CaM-kinases and their involvement in regulation of the cellular phosphorylation balance
2004 - 2006 にせ信号のない超高感度新型測定装置によるFDCDの基礎的研究
2002 - 2003 FDCDを利用した有機小分子の絶対配置決定に関する基礎的研究
2000 - 2001 FDCDを利用した複合体中の特定有機化合物の選択的CD測定研究
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Papers (79):
Yasser El Halmouch, Hassan A.H. Ibrahim, Nourhan M. Dofdaa, Mona E.M. Mabrouk, Mohammad Magdy El-Metwally, Tatsuo Nehira, Khalid Ferji, Yasuhiro Ishihara, Koichi Matsuo, Mohamed I.A. Ibrahim. Complementary spectroscopy studies and potential activities of Levan-type fructan produced by Bacillus paralicheniformis ND2. Carbohydrate Polymers. 2023. 311. 120743
Fujikawa, Aya, Ishihara, Yasuhiro, Ohta, Emi, Nehira, Tatsuo, Omura, Hisashi, Uy, Mylene M., Ohta, Shinji. Isolation of Fluorescent Benzoxazines with Neuroprotective Activity from the Olive Weevil Pimelocerus perforatus. JOURNAL OF NATURAL PRODUCTS. 2022. 85. 10. 2740-2745
Higashi, Reina, Ohta, Emi, Nehira, Tatsuo, Omura, Hisashi, Uy, Mylene M., Ohta, Shinji. Acylated secoiridoid glucosides isolated from the fruit extract of Symplocos lucida inhibit beta-glucuronidase. PHYTOCHEMISTRY LETTERS. 2022. 51. 127-131
Kawakami, Susumu, Inagaki, Masanori, Nishimura, Motohiro, Otsuka, Hideaki, Matsunami, Katsuyoshi, Nehira, Tatsuo, Shinzato, Takakazu. Crotofolane-Type Diterpenoids: Crotocascarins R-V, Rearranged Trinorcrotofolane: Crotocascarin delta and a Phorbol Derivative from the Leaves of Croton cascarilloides. CHEMICAL & PHARMACEUTICAL BULLETIN. 2022. 70. 4. 286-292
Kazutoshi Akizuki, Shun Ishikawa, Rika Obatake, Hana Ozaki, Nao Shimoda, Tatsuo Nehira, Takeshi Yamazaki, Tomoya Kinumi, Jin Osawa, Noriyuki Sueyoshi, Isamu Kameshita, Yasushi Shigeri, Atsuhiko Ishida. CaM kinase phosphatase (CaMKP/PPM1F/POPX2) is specifically inactivated through gallate-mediated protein carbonylation. Archives of Biochemistry and Biophysics. 2022. 720. 109170-109170
Development of a new fluorescent substrate PoLys-CUP for CaM kinase phosphatase
(2024)
Natural polyphenol compounds with pyrogallol structure specifically inactivate CaM kinase phosphatase (CaMKP/PPM1F/POPX2) by protein carbonylation
(2024)
Toward a Versatile Method for Determination of Absolute Configuration for Chiral Allenes Using Vacuum Ultraviolet Circular Dichroism
(19th International Conference on Chiroptical Spectroscopy (CD2023) 2023)
Circular Dichroic Spectroscopy beyond Exciton Coupling: Some Examples of Stereochemical Analysis
(SKCM2 Seminar WPI Hiroshima University 2023)
Circular Dichroic Spectroscopy beyond Exciton Coupling: A Research Collection of a Small Lab
(Hunter College Seminar 2022)