Rchr
J-GLOBAL ID：200901072722483790   Update date: Nov. 12, 2025

Jiro Kondo

コンドウ ジロウ | Jiro Kondo
Affiliation and department：
Sophia University Faculty of Science and Technology, Department of Materials and Life Sciences

About Sophia University Faculty of Science and Technology, Department of Materials and Life Sciences


Job title： Professor
Homepage URL  (1)： https://jkondo.wixsite.com/sophia-biophysics
Research field  (3)： Pharmaceuticals - analytical and physicochemistry ,  Biophysics ,  Structural biochemistry
Research keywords  (5)： X-Ray crystallography ,  Drug resistance ,  Antibiotics ,  生体機能応用デバイス ,  物理系薬学
Research theme for competitive and other funds  (37)：
  • 2022 - 2027 RNAターゲット創薬のためのRNA分子設計・共結晶化・試料調製支援と高度化
  • 2024 - 2026 疾病関連マイクロRNAと低分子リガンド複合体の立体構造解析
  • 2023 - 2026 Development of novel nucleic acid therapeutics by structural biomimetics
  • 2023 - 2026 アナログ分子模型・デジタル画像処理融合型分子モデリングツールの開発
  • 2023 - 2025 蛍光性DNA-銀ナノクラスターのX線結晶解析
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Papers (118)：
  • Kai Kosugi, Ayano Sugawara, Erika Iwase, HeeJu Park, Shoji Fujiwara, Hiroki Kanazawa, Akira Ono, Jiro Kondo. Gold-Mediated Base Pairs in Nucleic Acids: Selective Coordination to Natural and Thiocarbonyl-Modified Cytosines Dependent upon the Oxidation State of Gold. Chembiochem : a European journal of chemical biology. 2025. e202500565
  • Juanjuan Ye, Futoshi Suizu, Keiko Yamakawa, Hiroyuki Yoneyama, Jiro Kondo, Motohiko Kato, Akira Nishiyama, Naohisa Yahagi, Kyuichi Kadota. Stromal modifying CHST15 siRNA enhances antitumor effect synergistically with anti-PD-1 immune checkpoint antibody in murine pancreatic cancer. Scientific reports. 2025. 15. 1. 20365-20365
  • Hidetaka Torigoe, Kei Hirabayashi, Saki Adachi, Jiro Kondo. Novel specific binding of copper ions to naturally modified base pairs involving 5-fluorouracil in duplex DNA. Dalton Transactions. 2025. 54. 7208-7213
  • Takahiro Atsugi, Shoji Fujiwara, Jiro Kondo, Akira Ono. Synthesis and Metal-Ion Binding Properties of Duplexes Containing Thymine Analogs with 1,2-Diamine Groups. ChemBioChem. 2025. e2500017
  • Takumi Miyauchi, Kanna Yamaguchi, Satomi Saisu, Jiro Kondo. Structure-based design of a sequence-specific RNA probe that mimics the kink-turn motif. NAR Molecular Medicine. 2025. 2. 1. ugaf006
ｍore...
MISC (12)：
  • Jiro Kondo. Methods for Structure-based Design of Nucleic Acid Medicine. Bioindustry. 2018. 35. 3. 56-64
  • 大樂武範, 古板恭子, 佐藤一, 小野哲也, 吉田健太郎, 柏木良友, 中島勝幸, 近藤次郎, 根東義則, 小野晶, et al. 多核NMR分光法によるメタロ塩基対の構造決定. 日本薬学会年会要旨集(CD-ROM). 2018. 138th
  • Structure-Based Design of DNA Nanomedicine. 2016. 67. 11. 828-836
  • Jiro Kondo. Structure-Based Design of DNA nanomedicine. Chemical Industry. 2016. 27. 11. 28-36
  • Jiro Kondo. Frontier of Nucleic Acids Structural Biology. SOPHIA SCI-TECH. 2016. 27. 2-7
ｍore...
Patents (5)：
  • 核酸塩基検出剤
  • 金属イオン捕捉剤
  • 蛍光標識核酸プローブ
  • 特定の立体構造を誘導する人工核酸
  • DNA-金属ハイブリッドナノワイヤーおよびその製造方法
Books (10)：
  • 核酸医薬 モダリティ・合成・分析・DDSの最新動向
    NTS 2024
  • 生体高分子結晶のX線構造解析: -実践手法と基礎理論-
    2022 ISBN:4621307061
  • Handbook of Nucleic Acids Science
    講談社サイエンティフィク 2020
  • BasePairPuzzle
    2019
  • Nucleic Acid Crystallography -Methods and Protocols (Methods in molecular biology (Clifton, N.J.), v. 1320.; Springer protocols (Series) ) "Crystallographic Studies of the Ribosomal A-Site Molecular Switches by Using Model RNA Oligomers"
    Springer 2016 ISBN:9781493927623
ｍore...
Lectures and oral presentations  (154)：
  • 核酸の立体構造情報を活用した核酸医薬品のデザインと開発
    (一般財団法人バイオインダストリー協会 創薬モダリティ基盤研究会/ 講演会 2025)
  • tRNA sample preparation for structural study
    (Microbes & RNA 2025 2025)
  • RNAの立体構造の本質的な理解にむけて
    (RNAインフォマティクス道場2025 2025)
  • BasePairPuzzle: Molecular model for understanding the concept of RNA base pairing
    (29th tRNA Conference 2024)
  • Verification and classification of structural motifs observed in ribosomal RNA
    (29th tRNA Conference 2024)
ｍore...
Education (3)：
  • 2001 - 2004 Tokyo Institute of Technology Graduate School, Division of Life Science and Engineering
  • 1999 - 2001 Tokyo Institute of Technology Graduate School, Division of Life Science and Engineering
  • 1995 - 1999 Ritsumeikan University Faculty of Science and Engineering
Professional career (3)：
  • 学士(工学) (立命館大学)
  • 修士(理学) (東京工業大学)
  • 博士(理学) (東京工業大学)
Work history (6)：
  • 2023/04 - 現在 Sophia University Faculty of Science and Technology Department of Materials and Life Sciences Professor
  • 2015/04 - 2023/03 Sophia University Faculty of Science and Technology Department of Materials and Life Sciences Associate Professor
  • 2010/04 - 2015/03 Sophia University Faculty of Science and Technology Department of Materials and Life Sciences Assistant Professor
  • 2009/01 - 2010/03 Universite de Strasbourg Postdoctoral fellow
  • 2006/04 - 2008/12 Universite Louis Pasteur Postdoctoral fellow
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Awards (8)：
  • 2023/11 - Japan Society of Kansei Engineering Kawaii Kansei Design Award BasePairPuzzle
  • 2022/03 - Sophia University Attractive Lecture Award 2020
  • 2020/03/31 - 田中貴金属記念財団 2019年度「貴金属に関わる研究助成金」奨励賞
  • 2018/12/18 - 上智大学理工学部 Attractive Lecture Award 2018 生物物理学
  • 2017/12/19 - 上智大学理工学部 Attractive Lecture Award 2017 基礎生物学
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Association Membership(s) (11)：
日本結晶学会 ,  The RNA Society ,  日本RNA学会 ,  日本化学会 ,  日本生化学会 ,  日本薬学会 ,  日本生物物理学会 ,  IS3NA (The International Society of Nucleosides, Nucleotides & Nucleic Acids) ,  日本核酸医薬学会 ,  日本核酸化学会 ,  ホスト-ゲスト・超分子化学研究会
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