Jiro Kondo

コンドウジロウ | Jiro Kondo

Affiliation and department：
Job title： Professor
Homepage URL (1)： https://jkondo.wixsite.com/sophia-biophysics

Research field (3)： Pharmaceuticals - analytical and physicochemistry , Biophysics , Structural biochemistry

Research keywords (5)： X-Ray crystallography , Drug resistance , Antibiotics , 生体機能応用デバイス , 物理系薬学

Research theme for competitive and other funds (36)：

2022 - 2027 RNAターゲット創薬のためのRNA分子設計・共結晶化・試料調製支援と高度化
2024 - 2026 疾病関連マイクロRNAと低分子リガンド複合体の立体構造解析
2023 - 2026 Development of novel nucleic acid therapeutics by structural biomimetics
2023 - 2026 アナログ分子模型・デジタル画像処理融合型分子モデリングツールの開発
2023 - 2025 蛍光性DNA-銀ナノクラスターのX線結晶解析

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Papers (109)：

Takenori Dairaku, Kanako Nozawa-Kumada, Tetsuya Ono, Kentaro Yoshida, Yoshitomo Kashiwagi, Yoshiyuki Tanaka, Jiro Kondo, Makoto Tanabe. DNA Duplex Containing Ag⁺-Mediated Cytosine-Cytosine Base Pairs as a Catalyst Precursor for the 4-Nitrophenol Reduction with NaBH₄. Inorganic Chemistry. 2024
Kohei Nomura, Seongjin An, Yoshiaki Kobayashi, Jiro Kondo, Ting Shi, Hirotaka Murase, Kosuke Nakamoto, Yasuaki Kimura, Naoko Abe, Kumiko Ui-Tei, et al. Synthesis of 2′-formamidonucleoside phosphoramidites for suppressing the seed-based off-target effects of siRNAs. Nucleic Acids Research. 2024. 52. 10754-10774
Vanessa Rück, Vlad A. Neacșu, Mikkel B. Liisberg, Christian B. Mollerup, Park Hee Ju, Tom Vosch, Jiro Kondo, Cecilia Cerretani. Atomic Structure of a DNA-Stabilized Ag₁₁ Nanocluster with Four Valence Electrons. Advanced Optical Materials. 2024. 12. 7. 2301928
近藤次郎. RNAターゲット創薬とRNA創薬のための立体構造解析戦略. 実験医学増刊号. 2024. 42. 2. 129-135
Anna Gonzàlez-Rosell, Sami Malola, Rweetuparna Guha, Nery R. Arevalos, María Francisca Matus, Meghen E. Goule, Esa Haapaniemi, Benjamin B. Katz, Tom Vosch, Jiro Kondo, et al. Chloride Ligands on DNA-Stabilized Silver Nanoclusters. Journal of the American Chemical Society. 2023

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MISC (8)：

Jiro Kondo. Methods for Structure-based Design of Nucleic Acid Medicine. Bioindustry. 2018. 35. 3. 56-64
Structure-Based Design of DNA Nanomedicine. 2016. 67. 11. 828-836
Jiro Kondo. Structure-Based Design of DNA nanomedicine. Chemical Industry. 2016. 27. 11. 28-36
Jiro Kondo. Frontier of Nucleic Acids Structural Biology. SOPHIA SCI-TECH. 2016. 27. 2-7
Jiro Kondo. Understanding functions of non-coding RNAs by looking at their motions. Bulletin of The RNA Society of Japan. 2015. 32. 12-14

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Patents (5)：

核酸塩基検出剤
金属イオン捕捉剤
蛍光標識核酸プローブ
特定の立体構造を誘導する人工核酸
DNA-金属ハイブリッドナノワイヤーおよびその製造方法

Books (10)：

核酸医薬モダリティ・合成・分析・DDSの最新動向
NTS 2024
生体高分子結晶のX線構造解析: -実践手法と基礎理論-
2022 ISBN:4621307061
Handbook of Nucleic Acids Science
講談社サイエンティフィク 2020
BasePairPuzzle
2019
Nucleic Acid Crystallography -Methods and Protocols (Methods in molecular biology (Clifton, N.J.), v. 1320.; Springer protocols (Series) ) "Crystallographic Studies of the Ribosomal A-Site Molecular Switches by Using Model RNA Oligomers"
Springer 2016 ISBN:9781493927623

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Lectures and oral presentations (143)：

Participation Report on RNA 3D structure prediction at CASP16: Usage and limitations of AlphaFold3
(1st Asia&Pacific Bioinformatics Joint Conference 2024)
How does the number of bases in loops of G-rich repeats affect the formation of G-quadruplexes and their stability?
(XXV International Round Table on Nucleosides, Nucleotides and Nucleic Acids (IRT2024) 2024)
X-ray Crystallography of Nucleic Acids by the Counter-diffusion Method in a Microgravity Environment
(XXV International Round Table on Nucleosides, Nucleotides and Nucleic Acids (IRT2024) 2024)
Educational tools for learning the three-dimensional structure of nucleic acids
(XXV International Round Table on Nucleosides, Nucleotides and Nucleic Acids (IRT2024) 2024)
2’位化学修飾核酸の導入によるsiRNAの標的特異性の向上
(日本核酸医薬学会第9回年会 2024)

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Education (3)：

2001 - 2004 Tokyo Institute of Technology Graduate School, Division of Life Science and Engineering
1999 - 2001 Tokyo Institute of Technology Graduate School, Division of Life Science and Engineering
1995 - 1999 Ritsumeikan University Faculty of Science and Engineering

Professional career (3)：

学士(工学) (立命館大学)
修士(理学) (東京工業大学)
博士(理学) (東京工業大学)

Work history (6)：

2023/04 - 現在 Sophia University Faculty of Science and Technology Department of Materials and Life Sciences Professor
2015/04 - 2023/03 Sophia University Faculty of Science and Technology Department of Materials and Life Sciences Associate Professor
2010/04 - 2015/03 Sophia University Faculty of Science and Technology Department of Materials and Life Sciences Assistant Professor
2009/01 - 2010/03 Universite de Strasbourg Postdoctoral fellow
2006/04 - 2008/12 Universite Louis Pasteur Postdoctoral fellow

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Awards (8)：

2023/11 - Japan Society of Kansei Engineering Kawaii Kansei Design Award BasePairPuzzle
2022/03 - Sophia University Attractive Lecture Award 2020
2020/03/31 - 田中貴金属記念財団 2019年度「貴金属に関わる研究助成金」奨励賞
2018/12/18 - 上智大学理工学部 Attractive Lecture Award 2018 生物物理学
2017/12/19 - 上智大学理工学部 Attractive Lecture Award 2017 基礎生物学

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Association Membership(s) (11)：

日本結晶学会 , The RNA Society , 日本RNA学会 , 日本化学会 , 日本生化学会 , 日本薬学会 , 日本生物物理学会 , IS3NA (The International Society of Nucleosides, Nucleotides & Nucleic Acids) , 日本核酸医薬学会 , 日本核酸化学会 , ホスト-ゲスト・超分子化学研究会

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