Rchr
J-GLOBAL ID：200901072844936183
Update date: May. 20, 2024
Namba Kazunori
ナンバカズ ノリ | Namba Kazunori
Affiliation and department：
Homepage URL (1)：
http://www.kankakuki.go.jp/lab_c-1.html
Research field (6)：
Pharmaceuticals - chemistry and drug development
, Pharmacology
, Pharmaceuticals - health and biochemistry
, Molecular biochemistry
, Laboratory animal science
, Neuroscience - general
Research keywords (5)：
蛋白質科学
, 遺伝学
, 構造生物学
, 受容体
, 脳神経科学
Research theme for competitive and other funds (5)：
- 2018 - 2022 Construction of a mouse model for Auditory Neuropathy Spectrum Disorder
- 2015 - 2018 Molecular functional analysis of ZBTB10, the novel candidate deafness gene associated with cochlear nerve hypoplasia
- 2015 - 2017 ペンドレッド症候群の原因となるSLC26A4の高頻出変異による構造障害機序の解明
- 2012 - 2014 OTOF欠損マウスを用いたAuditoryNeuropathyの障害モデルの構築
- 2010 - 2011 The structural study aim to elucidate congenital hearing loss caused by OTOF gene mutation
Papers (28)：
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Namba K, Mutai H, Matsunaga T, Kaneko H. Structural basis for pathogenic variants of GJB2 and hearing levels of patients with hearing loss. BMC Res Notes. 2024. 17. 131
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Nobuyoshi Tsuzuki, Kazunori Namba, Chika Saegusa, Hideki Mutai, Takanori Nishiyama, Naoki Oishi, Tatsuo Matsunaga, Masato Fujioka, Hiroyuki Ozawa. Apoptosis of type I spiral ganglion neuron cells in Otof-mutant mice. Neuroscience letters. 2023. 803. 137178-137178
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Nobuko Yamamoto, Hideki Mutai, Kazunori Namba, Fumiyuki Goto, Kaoru Ogawa, Tatsuo Matsunaga. Clinical Profiles of DFNA11 at Diverse Stages of Development and Aging in a Large Family Identified by Linkage Analysis. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2020. 41. 6. e663-e673
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Kitao K, Mutai H, Namba K, Morimoto N, Nakano A, Arimoto Y, Sugiuchi T, Masuda S, Okamoto Y, Morita N, et al. Deterioration in Distortion Product Otoacoustic Emissions in Auditory Neuropathy Patients With Distinct Clinical and Genetic Backgrounds. Ear and hearing. 2018. 40. 1. 184-191
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Nobuko Yamamoto, Hideki Mutai, Kazunori Namba, Noriko Morita, Shin Masuda, Yasuyuki Nishi, Atsuko Nakano, Sawako Masuda, Masato Fujioka, Kimitaka Kaga, et al. Prevalence of TECTA mutation in patients with mid-frequency sensorineural hearing loss. ORPHANET JOURNAL OF RARE DISEASES. 2017. 12
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MISC (33)：
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難波 一徳, 務台 英樹, 松永 達雄. 難聴モデルOtof欠損マウスのらせん神経節細胞の神経栄養因子の減少を伴うアポトーシス. Otology Japan. 2017. 27. 4. 541-541
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山本 修子, 難波 一徳, 務台 英樹, 森田 訓子, 松永 達雄. TECTA蛋白の構造解析による新規変異の分子病態予測. Otology Japan. 2017. 27. 4. 547-547
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松永達雄, 務台英樹, 難波一徳, 奈良清光. 国際標準に立脚した奇形症候群領域の診療指針に関する学際的・網羅的検討 ワルデンブルグ症候群1型の非典型的な遺伝的原因の解明. 国際標準に立脚した奇形症候群領域の診療指針に関する学際的・網羅的検討 平成28年度 総括・分担研究報告書(Web). 2017. 41-44 (WEB ONLY)
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Minami Shujiro B, Mutai Hideki, Namba Kazunori, Sakamoto Hirokazu, Matsunaga Tatsuo. Clinical characteristics of a Japanese family with hearing loss accompanied by compound heterozygous mutations in LOXHD1. Nippon Jibiinkoka Gakkai Kaiho. 2017. 120. 6. 882-883
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難波 一徳, 松永 達雄. オーディトリーニューロパチーを呈するマウスモデルにより示された蝸牛神経節形成異常の病態解析. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [3P1266]-[3P1266]
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Books (2)：
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Molecular modeling-based investigations of a mutant protein in patients with hearing loss
Pharmacology 2014
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Distribution and relative expression of homo- and heteromeric purinergic adenosine A1 and P2Y receptors assessed by quantitative immunogold electron microscopy
InTech-MS Biochemistry 2011
Association Membership(s) (2)：
THE JAPAN OTOLOGICAL SOCIETY
, THE JAPANESE BIOCHEMICAL SOCIETY
