Yamada Takeshi

ヤマダタケシ | Yamada Takeshi

Affiliation and department：
Job title： Lecture

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (2)： Natural Product Chemistry , Natural products

Research theme for competitive and other funds (7)：

2014 - 2017 Search of the seeds of an antineoplastic drug and development of a lead compound which marine organism origin fungi produce
2011 - 2013 Search of the seeds of an antineoplastic drug and development of a lead compound which marine organism origin fungi produce
2009 - 2011 Research and development of drugs of prevention and treatment for complication of diabetes targeting the receptor of advanced glycation end products(RAGE)
2000 - 2002 Search and development of antitumor sed compounds produced yb microorganisms from marine organisms
1998 - 1999 Development of antitumor lead compounds produced by microorganisms from marine organisms

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Papers (143)：

Takashi Kikuchi, Daichi Anami, Shota Morikawa, Yuki Nakagawa, Takeshi Yamada, Wei Li, Tomoya Hirano. Secoergostane- and ergostane-type steroids from Pleurotus cornucopiae var. citrinopileatus. Phytochemistry. 2023. 206. 113552-113552
Akifumi Nagatomo, Kiyofumi Ninomiya, Shinsuke Marumoto, Chie Sakai, Shuta Watanabe, Wakana Ishikawa, Yoshiaki Manse, Takashi Kikuchi, Takeshi Yamada, Reiko Tanaka, et al. A Gedunin-Type Limonoid, 7-Deacetoxy-7-Oxogedunin, from Andiroba (Carapa guianensis Aublet) Reduced Intracellular Triglyceride Content and Enhanced Autophagy in HepG2 Cells. International journal of molecular sciences. 2022. 23. 21
Yoshihide Usami, Kimika Nakamura, Yoshino Mizobuchi, Koji Mizuki, Shinya Harusawa, Hiroki Yoneyama, Takeshi Yamada. Enantiomeric composition of natural pericosine A derived from Periconia byssoides and alpha-glycosidase inhibitory activity of (-)-enantiomer. CHIRALITY. 2022
Yoshihide Usami, Yoshino Mizobuchi, Mai Ijuin, Takeshi Yamada, Mizuki Morita, Koji Mizuki, Hiroki Yoneyama, Shinya Harusawa. Synthesis of 6-Halo-Substituted Pericosine A and an Evaluation of Their Antitumor and Antiglycosidase Activities. Marine drugs. 2022. 20. 7
Takeshi Yamada, Kanoko Yoshida, Takashi Kikuchi, Tomoya Hirano. Isolation and Structure Elucidation of New Cytotoxic Macrolides Halosmysins B and C from the Fungus Halosphaeriaceae sp. Associated with a Marine Alga. Marine drugs. 2022. 20. 4

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MISC (66)：

長友暁史, 二宮清文, 二宮清文, 丸本真輔, 酒井千恵, 村岡修, 村岡修, 菊池崇, 山田剛司, 田中麗子, et al. Reducing Effects of Limonoids from Andiroba (Carapa guianensis) on Intracellular Triglyceride Contents and Its Mode of Action. 香料・テルペンおよび精油化学に関する討論会講演要旨集. 2021. 65th
山田剛司, 片岡美波, 菊地崇, 平野智也. The absolute stereostructure of novel macrolide produced by a marine alga-derived fungus. 日本薬学会年会要旨集(Web). 2021. 141st
長友暁史, 二宮清文, 二宮清文, 丸本真輔, 酒井千恵, 村岡修, 村岡修, 菊池崇, 山田剛司, 田中麗子, et al. ブラジル生薬アンディローバ(Carapa guianensis)由来リモノイドのオートファジーを介した細胞内中性脂肪低減作用. 日本栄養・食糧学会大会講演要旨集. 2021. 75th
長友暁史, 二宮清文, 二宮清文, 丸本真輔, 酒井千恵, 村岡修, 村岡修, 菊池崇, 山田剛司, 田中麗子, et al. Evaluation of improving effects of limonoids from Andiroba (Carapa guianensis) on lipid metabolism using HepG2 cells. 日本薬学会年会要旨集(Web). 2021. 141st
山田剛司, 木暮遥, 菊地崇. The chemical structure of novel macrolide produced by a marine alga-derived fungus. 日本薬学会年会要旨集(CD-ROM). 2020. 140th

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Patents (4)：

Education (2)：

- 1994 Osaka University of Pharmaceutical Sciences Graduate School of Pharmaceutical Sciences
- 1994 Osaka University of Pharmaceutical Sciences Graduate School, Division of Pharmaceutical Sciences

Professional career (2)：

Association Membership(s) (2)：

THE JAPANESE SOCIETY OF PHARMACOGNOSY , 日本薬学会

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