Kanaho Yasunori

カナホヤスノリ | Kanaho Yasunori

Affiliation and department：
Job title： Executive Director
Homepage URL (1)： http://www.md.tsukuba.ac.jp/basic-med/biochem/kanaholab/index.html

Research field (1)： Functional biochemistry

Research keywords (8)： Cancer , Morphogenesis , cell motility , Cell Function , Knockout mouse , Newroscience , Small G protein , Lipid signaling

Research theme for competitive and other funds (8)：

2021 - 2023 炎症応答の鍵分子としての低分子量G蛋白質Arf6の解析
2018 - 2020 革新的抗癌剤の開発に向けた腫瘍血管新生と癌転移の阻害ペプチドの創成
2015 - 2017 Development of peptides inhibiting tumor angiogenesis and metastasis to develop novel anti-cancer drug
2008 - 2010 Physiological functions of lipid signaling molecule-producing enzymes based on their search of partner proteins
2007 - 2009 Exploration of bioactive compounds from traditional medicinal plants in Vietnam

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Papers (175)：

Ogura, Yukino, Ohbayashi, Norihiko, Kanaho, Yasunori, Kawaguchi, Atsushi, Funakoshi, Yuji. Ubiquitin-specific protease TRE17/USP6 promotes tumor cell invasion through the regulation of glycoprotein CD147 intracellular trafficking. JOURNAL OF BIOLOGICAL CHEMISTRY. 2022. 298. 9
Gamara, Jouda, Davis, Lynn, Leong, Andrew Z, Page, Nathalie, Rollet-Labelle, Emmanuelle, Zhao, Chenqi, Hongu, Tsunaki, Funakoshi, Yuji, Kanaho, Yasunori, Aoudji, Fawzi, et al. Arf6 regulates energy metabolism in neutrophils. FREE RADICAL BIOLOGY AND MEDICINE. 2021. 172. 550-561
Lee, SangJoon, Ishitsuka, Akari, Kuroki, Takahiro, Lin, Yu-Hsien, Shibuya, Akira, Hongu, Tsunaki, Funakoshi, Yuji, Kanaho, Yasunori, Nagata, Kyosuke, Kawaguchi, Atsushi. Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes. JCI INSIGHT. 2021. 6. 16
Sumiyoshi, Mami, Kotani, Yui, Ikuta, Yuki, Suzue, Kazutomo, Ozawa, Madoka, Katakai, Tomoya, Yamada, Taketo, Abe, Takaya, Bando, Kana, Koyasu, Shigeo, et al. Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation. JOURNAL OF IMMUNOLOGY. 2021. 206. 2. 366-375
Nguyen, Thi Kim Nguyen, Ohbayashi, Norihiko, Kanaho, Yasunori, Funakoshi, Yuji. TBC1D24 regulates recycling of clathrin-independent cargo proteins mediated by tubular recycling endosomes. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2020. 528. 1. 220-226

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Patents (4)：

Arf6遺伝子機能喪失動物及びその利用方法
GTP結合型ARF6タンパク質の測定方法及びその用途
Arf6遺伝子機能喪失動物及びその利用方法
アレルギーマウス

Books (28)：

Diverse functions of phospholipase D in cancer
2019
Common Diseaseの病態生理と薬物療法
オーム社 2019 ISBN:9784274220708
Common Diseaseの病態生理と薬物治療
オーム社 2019 ISBN:9784274220708
Canser Sci
Japanese Cancer Association 2018
生化学
2016

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Lectures and oral presentations (104)：

脱ユビキチン化酵素TRE17/USP6による膜タンパク質の輸送制御を介した腫瘍細胞の浸潤促進機構脱ユビキチン化酵素TRE17/USP6による膜タンパク質の輸送制御を介した腫瘍細胞の浸潤促進機構
(第45回日本分子生物学会年会)
Ubiquitin-specific protease TRE17/USP6 promotes tumor cell invasion through the regulation of plasma membrane protein intracellular trafficking
(第45回分子生物学会年会)
脱ユビキチン化酵素TRE17/USP6は、CD147の細胞内輸送制御を介してがん細胞浸潤能を亢進する
(第19回生命科学研究会)
Ubiquitin-specific protease TRE17/USP6 promotes cancer cell invasion through the regulation of plasma membrane protein recycling
(The 2020 NTU-KU-UT mini-symposium on Cancer Biology and Medicine 2021)
脱ユビキチン化酵素TRE17/USP6は膜蛋白質のリサイクリングを介して癌細胞浸潤能を亢進する
(第43回日本分子生物学会 2020)

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Education (1)：

- 1982 Kyoto Pharmaceutical University Graduate School, Division of Pharmaceutical Sciences

Professional career (1)：

薬学博士 (京都薬科大学)

Work history (8)：

2011/10 - 現在 University of Tsukuba Faculty of Medicine
2005/04 - 現在筑波大学大学院人間総合科学研究科教授
1999/10 - 2005/03 (財)東京都臨床医学総合研究所部長
1993/04 - 1999/09 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology
1989/03 - 1993/03 Gifu University School of Medicine

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Association Membership(s) (4)：

THE JAPANESE BIOCHEMICAL SOCIETY , Japan Society for Cell Biology , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPANESE CONFERENCE ON THE BIOCHEMISRTY OF LIPIDS

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