Rchr
J-GLOBAL ID:200901073428295450   Update date: Nov. 01, 2024

KAZUO SHINOZUKA

シノヅカ カズオ | KAZUO SHINOZUKA
Affiliation and department:
Job title: Professor
Research field  (1): Bioorganic chemistry
Research theme for competitive and other funds  (18):
  • 2014 - 2017 Development of fluorogenic probe for gene-analisis utilizing novel silylated fluorescent material
  • 2012 - 2014 Development of fluorogenic probe for gene-analisis utilizing novel sililated fluorescent material
  • 2006 - 2007 生体膜コレステロール組成を感知する蛍光プローブの開発
  • 2003 - 2005 Functionalization of oligonucleotides capable to form alternate-stranded triplex containing stereoisomeric nucleotide units
  • 2001 - 2004 Enzymatic Synthesis of Modified DNAs by PCR, and Their Application
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Papers (10):
  • Shiyu Wang, Md Zakir Hossain, Tao Han, Kazuo Shinozuka, Takaaki Suzuki, Anna Kuwana, Haruo Kobayashi. Avidin-Biotin Technology in Gold Nanoparticle-Decorated Graphene Field Effect Transistors for Detection of Biotinylated Macromolecules with Ultrahigh Sensitivity and Specificity. ACS omega. 2020. 5. 46. 30037-30046
  • Shiyu Wang, Md Zakir Hossain, Kazuo Shinozuka, Natsuhiko Shimizu, Shunya Kitada, Takaaki Suzuki, Ryo Ichige, Anna Kuwana, Haruo Kobayashi. Graphene field-effect transistor biosensor for detection of biotin with ultrahigh sensitivity and specificity. Biosensors & bioelectronics. 2020. 165. 112363-112363
  • Shiyu Wang, Md. Zakir Hossain, Takaaki Suzuki, Kazuo Shinozuka, Natsuhiko Shimizu, Shunya Kitada, Ryo Ichige, Anna Kuwana, Haruo Kobayashi. Graphene biosensor for saliva protein adsorption. Proceedings of International Conference on ASIC. 2019
  • Eisuke Horigome, Michiru Fujieda, Tadashi Handa, Ayaka Katayama, Masashi Ito, Ami Ichihara, Daiki Tanaka, Navchaa Gombodorj, Shinji Yoshiyama, Arito Yamane, et al. Mutant TP53 modulates metastasis of triple negative breast cancer through adenosine A2b receptor signaling. Oncotarget. 2018. 9. 77. 34554--34566
  • Tomohisa Moriguchi, A T M Zafrul Azam, Kazuo Shinozuka. Synthesis and alternate-stranded triple helix forming ability of novel anthraquinone modified alpha-beta chimeric DNA. Nucleic acids symposium series (2004). 2005. 49. 7-8
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MISC (165):
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Patents (5):
  • シリル化蛍光剤を結合した核酸検出プロ-ブ、及び当該プロ-ブによる核酸の検出方法
  • 含ケイ素蛍光化合物および該化合物を用いた蛍光標識剤
  • Inhibitors for Replication of Retroviruses and for The Expression of On Cogene Products. U. S. Patent 5,264,423 and 5,276,019
  • Inhibitors for Replication of Retroviruses and for the Expression of Oncogene Products
  • Inhibitors for Replication of Retroviruses and for The Expression of On Cogene Products. U. S. Patent 5,264,423 and 5,276,019
Books (4):
  • Pyrene: Chemical Properties, Biochemistry Applications and Toxic Effects,
    Nova Science Publishers Inc. 2013
  • Pyrene: Chemical Properties, Biochemistry Applications and Toxic Effects,
    Nova Science Publishers Inc. 2013
  • ケミカルエンジニアリング
    化学工業社 2009
  • 細胞工学ハンドブック(共著)
    朝倉書店 2000
Lectures and oral presentations  (85):
  • 電子供与基を導入したシリル化ピレン及びそれを導入した人工核酸の開発
    (日本化学会第98春季年会 2018)
  • ベンゾフェノンを導入した光架橋性人工核酸の開発
    (日本化学会第98春季年会 2018)
  • Improvement of Sequence Discrimination Ability of Molecular Beacons by the Addition of Short Oligomers
    (The 44th International Symposium on Nucleic Acids Chemistry 2017)
  • ホスホチロシンを用いた新しいペプチド抗原の検討
    (日本化学会第97春季年会 2017)
  • 熱帯熱マラリア原虫エノラーゼの部分ペプチドを用いた、ヒトプラスミノーゲン結合配列とプラスミン活性化の研究
    (日本化学会第97春季年会 2017)
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Works (6):
  • 抗ガン剤シスプラチンの作用機序に関する研究
    1998 - 2000
  • Mechanistic study about cis-platin
    1998 - 2000
  • 機能性修飾オリゴ核酸の合成
    1997 -
  • Synthesis of functionalized oligodeoxynucleotides
    1997 -
  • 高活性・低毒性な新規アンチセンス試材の開発, 及びその抗エイズ薬としての応用
    1995 -
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Education (4):
  • - 1982 オーストラリア国立ジョーンカーティン医学研究校大学院 医薬化学研究科 医薬化学
  • - 1982 Australian National University. The John Curtin School of Medical Research Medicinal Chemistry Medicinal Chemistry
  • - 1977 Kumamoto University School of Pharmacy
  • - 1977 Kumamoto University Faculty of Pharmaceutical Science
Professional career (1):
  • Ph. D (The Australian National University)
Work history (11):
  • 2000/04 - 2019/03 Gunma University Graduate School of Science and Technology Professor
  • 1993 - 2000 Gunma University
  • 1993 - 2000 Gunma University Assistant Professor
  • 1988 - 1993 Gunma University
  • 1988 - 1993 Gunma University Faculty of Engineering Research Assistant
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Committee career (6):
  • 1997 - 2001 : 日本薬学会 関東支部幹事
  • 1991 - -: アンチセンス研究会 運営委員
  • 日本核酸医薬学会 評議員 監事
  • 日本核酸化学会 評議員 監事
  • アンチセンスDNA/RNA研究会 幹事
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Awards (1):
  • 2021/11 - Japan Society of Nucleic Acids Chemistry The Award of Japan Society of Nucleic Acids Chemistry
Association Membership(s) (7):
日本核酸医薬学会 ,  日本核酸化学会 ,  アメリカ化学会 ,  アンチセンスDNA/RNA研究会 ,  日本薬学会 ,  日本化学会 ,  国際核酸化学会
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