Rchr
J-GLOBAL ID:200901073518187975
Update date: Sep. 28, 2024
Sugimoto Hiroshi
スギモト ヒロシ | Sugimoto Hiroshi
Affiliation and department:
Other affiliations (1):
Homepage URL (1):
http://www.riken.jp/biometal/index.htm
Research field (3):
Biophysics
, Structural biochemistry
, Molecular biochemistry
Research keywords (4):
トランスポーター
, 結晶構造解析
, ヘム
, X線
Research theme for competitive and other funds (21):
- 2021 - 2024 病原菌ヘムトランスポーターの構造変化の追跡と基質輸送機構の解明
- 2019 - 2024 Protein metalation that controls biometal dynamics in the cells
- 2020 - 2022 Structure of reactive oxygen species generated by heme-enzyme
- 2019 - 2021 Structure analysis of monooxygenase using XFEL and microfluidic device
- 2018 - 2021 Strucutral analysis of the membrane proteins involved in metal transport
- 2015 - 2021 生体触媒の誤作動状態を利用するメタンの直接的メタノール変換
- 2017 - 2019 Structural analysis of bacterial heme transporter
- 2015 - 2018 Development of time-resolved spectroscopic systems with micro-flow devices and their application to the molecular mechanism of ABC transporters
- 2015 - 2017 Structure and mechanism of the heme transporter
- 2012 - 2016 Structure and mechanism of the iron transport system in human
- 2013 - 2015 病原微生物におけるヘム獲得システムの構造基盤
- 2013 - 2015 病原微生物におけるヘム獲得システムの構造基盤
- 2011 - 2013 病原微生物におけるヘムシグナリング複合体の構造学的研究
- 2009 - 2012 Molecular Evolution of Respiratory Enzymes; Functional Conversion from NO Reduction to O2 Reduction
- 2009 - 2011 Protein Engineering of vitamin D hydroxylases and design of their inhibitors based on their tertiary structure
- 2008 - 2009 時間分割共鳴ラマン分光法による二原子酸素添加酵素の構造ダイナミクス
- 2007 - 2008 Analysis of oxygen activation mechanism in the heme-containing dioxygenases
- 2004 - 2007 Bio-conversion of Substances and Information by Metal-containing Proteins and Enzymes
- 2002 - 2004 Peroxygenase P450 as a Novel Bio-material
- 2002 - 2004 血管新生過程における情報伝達因子の構造学的研究
- 1998 - 1999 遺伝子工学と多波長異常分散法を利用した新しい蛋白質構造解析法の開発
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Papers (109):
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Rachel Bolton, Moritz M Machelett, Jack Stubbs, Danny Axford, Nicolas Caramello, Lucrezia Catapano, Martin Malý, Matthew J Rodrigues, Charlotte Cordery, Graham J Tizzard, et al. A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron-binding protein FutA from Prochlorococcus. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 12. e2308478121
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Hiroaki Inaba, Yuma Shisaka, Shinya Ariyasu, Erika Sakakibara, Garyo Ueda, Yuichiro Aiba, Nobutaka Shimizu, Hiroshi Sugimoto, Osami Shoji. Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom. RSC Advances. 2024. 14. 13. 8829-8836
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阪口 智哉, 澤井 仁美, 城 宜嗣, 鍔木 基成, 當舎 武彦, 木村 哲就, 杉本 宏. 鉄還元機能を持つ6回膜貫通型タンパク質101F6の大腸菌での発現と機能解析. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [2P-656]
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Joshua Kyle Stanfield, Hiroki Onoda, Shinya Ariyasu, Chie Kasai, Eleanor Mary Burfoot, Hiroshi Sugimoto, Osami Shoji. Investigating the applicability of the CYP102A1-decoy-molecule system to other members of the CYP102A subfamily. Journal of Inorganic Biochemistry. 2023. 245. 112235-112235
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Shinya Ariyasu, Kai Yonemura, Chie Kasai, Yuichiro Aiba, Hiroki Onoda, Yuma Shisaka, Hiroshi Sugimoto, Takehiko Tosha, Minoru Kubo, Takashi Kamachi, et al. Catalytic Oxidation of Methane by Wild-Type Cytochrome P450BM3 with Chemically Evolved Decoy Molecules. ACS Catalysis. 2023. 8613-8623
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MISC (116):
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阪口智哉, 澤井仁美, 城宜嗣, 鍔木基成, 當舎武彦, 木村哲就, 杉本宏. 鉄還元機能を持つ6回膜貫通型タンパク質101F6の大腸菌での発現と機能解析. 日本生化学会大会(Web). 2023. 96th
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NISHITANI Yudai, NISHINAGA Megumi, NAGAI Seina, SUGIMOTO Hiroshi, SUGIMOTO Hiroshi, TOSHA Takehiko, TOSHA Takehiko, SHIRO Yoshitsugu, SAWAI Hitomi, SAWAI Hitomi. Dual Function of the Heme Ligation in a Heme-responsive Sensor Protein, PefR. 日本蛋白質科学会年会プログラム・要旨集. 2020. 20th (Web)
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TAKAHARA Michiyo, FUJISHIRO Hitomi, KAMBE Taiho, SUGIMOTO Hiroshi, SUGIMOTO Hiroshi, SHIRO Yoshitsugu, SAWAI Hitomi, SAWAI Hitomi. Functional Analysis Of Membrane Proteins Involved In Iron Absorption Using Human Intestinal Model Cell System. 日本蛋白質科学会年会プログラム・要旨集. 2020. 20th (Web)
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西谷雄大, 西永惠, 長井聖奈, 杉本宏, 杉本宏, 當舎武彦, 當舎武彦, 城宣嗣, 澤井仁美, 澤井仁美. Structural and kinetic analysis of CO binding to bacterial heme-responsive sensor protein. 2020. 93rd
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澤井仁美, 澤井仁美, 西永惠, 長井聖奈, 長門石暁, 長門石暁, 津本浩平, 津本浩平, 杉本宏, 杉本宏, et al. 病原菌の鉄獲得システムで機能するヘムセンサータンパク質の構造機能相関の解明. 日本鉄バイオサイエンス学会学術集会プログラム・抄録集. 2019. 43rd
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Education (3):
- 1997 - 2000 Hokkaido University
- 1995 - 1997 Hokkaido University
- 1991 - 1995 北海道大学 理学部・高分子学科
Professional career (1):
Work history (7):
- 2018/04 - 現在 RIKEN
- 2017/04 - 現在 University of Hyogo of Life Science, Graduate School
- 2017/04 - RIKEN
- 2009/04 - RIKEN
- 2005/09 - RIKEN
- 2001/10 - 理化学研究所 生体物理化学研究室 研究員
- 2000/04 - 2001/09 Columbia University, USA (Wayne A. Hendrickson Lab) ポスドク研究員
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Association Membership(s) (6):
日本生物物理学会
, 日本結晶学会
, 日本化学会
, 日本放射光学会
, 日本蛋白質科学会
, 日本生化学会
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