Tan-No Koichi

タンノコウイチ | Tan-No Koichi

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://www.tohoku-pharm.ac.jp/laboinf/lab_yakuri.html

Research field (3)： Pharmacology , Pharmaceuticals - health and biochemistry , Neuroscience - general

Research keywords (7)：アンジオテンシン , 神経ペプチド , 鎮痛 , 痛み , Neuropeptides , Analgesia , Pain

Research theme for competitive and other funds (11)：

2020 - 2023 2型糖尿病に伴う神経障害性疼痛の解明:脊髄アンジオテンシン系の関与と治療薬の開発
2017 - 2020 糖尿病性神経障害性疼痛の解明と新規治療法の開発:脊髄アンジオテンシン系からの検討
2014 - 2018 A New Development of Molecular Design Utilizing Novel Hydrophobic Structures
2014 - 2017 Development of hippocampal neurogenesis-promoting drugs as a target for the treatment and prevention of psychiatric disorders
2014 - 2017 慢性疼痛における脊髄アンジオテンシン系の役割の解明:新規治療法の開発を目指して

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Papers (188)：

Takayo Odaira-Satoh, Osamu Nakagawasai, Kohei Takahashi, Ryotaro Ono, Miharu Wako, Wataru Nemoto, Koichi Tan-No. Captopril prevents depressive-like behavior in an animal model of depression by enhancing hippocampal neurogenesis via activation of the ACE2/Ang (1-7)/Mas receptor/AMPK/BDNF pathway. Progress in neuro-psychopharmacology & biological psychiatry. 2024. 111198-111198
Osamu Nakagawasai, Kohei Takahashi, Takuto Suzuki, Ryota Yamagata, Wataru Nemoto, Koichi Tan-No. Long-term effects of a single high-dose intraperitoneal injection of lipopolysaccharide on depression-like behavior in adolescent mice. Neuroscience letters. 2024. 137989-137989
Ryota Yamagata, Ai Saito, Ryoko Fukushima, Osamu Nakagawasai, Naoya Yamashita, Koichi Tan-No, Gi-Wook Hwang. Methylmercury exposure at dosage conditions that do not affect growth can impair memory in adolescent mice. Toxicological Research. 2024
Shiori Iwane, Wataru Nemoto, Tomoyoshi Miyamoto, Tomonori Hayashi, Masayuki Tanaka, Kazuki Uchitani, Tatsuya Muranaka, Masanori Fujitani, Yuichi Koizumi, Atsushi Hirata, et al. Clinical and preclinical evidence that angiotensin-converting enzyme inhibitors and angiotensin receptor blockers prevent diabetic peripheral neuropathy. Scientific Reports. 2024. 14. 1
Osamu Nakagawasai, Kohei Takahashi, Taisei Koyama, Ryota Yamagata, Wataru Nemoto, Koichi Tan-No. Activation of angiotensin-converting enzyme 2 produces an antidepressant-like effect via MAS receptors in mice. Molecular Brain. 2023. 16. 1

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MISC (156)：

冨田詩織, 冨田詩織, 根本亙, 宮本朋佳, 宮本朋佳, 林友典, 田中雅幸, 打谷和記, 村中達也, 小泉祐一, et al. Effects of angiotensin converting enzyme inhibitors or receptor blockers on diabetic peripheral neuropathy: clinical evidence supported by a preclinical study. 日本薬学会年会要旨集(Web). 2023. 143rd
中川西修, 山田耕太郎, 大島有湖, 根本亙, 高橋浩平, 高橋浩平, 笹川由香, 墨田康男, 丹野孝一. Anti-fatigue preventive effect of globin digest in mice. 日本薬学会年会要旨集(Web). 2023. 143rd
中川西修, 若生美春, 小平貴代, 小野涼太郎, 高橋浩平, 高橋浩平, 根本亙, 丹野孝一. Captoprilの抗うつ作用における海馬アンジオテンシン系の関与. 日本薬理学雑誌. 2022. 157. Supplement
根本亙, 山縣涼太, 中川西修, 丹野孝一. 脊髄内ADAM17のアップレギュレーションが2型糖尿病に伴う神経障害性疼痛に関与する. 日本神経化学会大会抄録集(Web). 2022. 65th
小野木弘志, 中川西修, 根本亙, 三反崎聖, 丹野孝一, 只野武. p-ヒドロキシアンフェタミン誘発性プレパルス抑制に対するセロトニン及びノルアドレナリン神経系の関与. 日本薬学会東北支部大会講演要旨集. 2022. 61st

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Books (2)：

Spantide-Induced Antinociception in the Mouse Formalin Test
Elsevier Science Publishers B. V. , Amsterdam 1992
Aversive Response Produced by Intrathecal Injection of NMDA in Mice ; Effects of Substance P and 5-HT Antagonists
NPP Books, Michigan 1991

Education (4)：

- 1987 東北薬科大学薬学研究科薬理学
- 1987 Tohoku Pharmaceutical University Graduate School, Division of Pharmaceutical Sciences
- 1985 東北薬科大学薬学部製薬
- 1985 Tohoku Pharmaceutical University Faculty of Pharmaceutical Science

Professional career (2)：

Work history (7)：

2016/04 - 現在 Tohoku Medical and Pharmaceutical University Faculty of Pharmaceutical Sciences
2011/04 - 2016/03 東北薬科大学教授
2007 - 2011/03 - 東北薬科大学准教授
2005 - 2007 東北薬科大学助教授
2001 - 2005 東北薬科大学講師

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Committee career (4)：

Awards (1)：

Association Membership(s) (6)：

国際麻薬研究評議会 , 鎮痛薬・オピオイドペプチド研究会 , 日本疼痛学会 , 日本薬学会 , 日本薬理学会 , THE JAPANESE SOCIETY FOR NEUROCHEMISTRY

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