Rchr
J-GLOBAL ID：200901074016292399
Update date: May. 08, 2025
Ando Joji
アンドウ ジヨウジ | Ando Joji
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
http://square.umin.ac.jp/~vascbiol/
Research field (5)：
Cardiology
, Clinical pharmacy
, Physiology
, Biomaterials
, Biomedical engineering
Research keywords (11)：
レオロジー
, バイオメカニクス
, 力学応答
, 血流
, 血管
, shear stress 内皮細胞
, biorheology
, biomechanics
, mechanotransduction
, endothelial cell
, shear stress
Research theme for competitive and other funds (50)：
- 2024 - 2027 血管内皮細胞が層流と乱流を区別するメカノセンシング機構
- 2021 - 2024 Mitochondria-mediated blood flow mechanosensing in endothelial cells
- 2019 - 2021 Bioenergetics of vascular endothelial mitochondria in response to blood flow stimuli
- 2018 - 2021 Blood flow-sensing mechanisms via lipid molecules in endothelial plasma membranes
- 2015 - 2017 A new in vitro research model for intracranial aneurysm to bridge the gap between biology and flow dynamics
- 2013 - 2016 Mechanoresponses of endothelial cell membranes to fluid shear stress
- 2014 - 2016 血管細胞における血流のメカノトランスダクション機構
- 2009 - 2014 血管細胞における力学応答の分子バイオメカニクス
- 2010 - 2012 Blood-flow-mediated mechanotransduction in vascular endothelial cells
- 2009 - 2009 内皮細胞における血流刺激のメカノトランスダクション機構の解明
- 2007 - 2009 Shear-stress-induced molecular dynamics of endothelial cell membrane
- 2005 - 2009 Biomechanical force-sensing and response mechanisms in vascular cells and its application to tissue engineering
- 2006 - 2008 Ion channel-mediated blood flow-sensing mechanism in vascular endothelial cells
- 2004 - 2006 Generating blood-flow-sensing-molecule-deficient mice and analysis of their physiological functions
- 2003 - 2005 Mechano-sensing Mechanism and Mechano-Responsive Genes in Vascular Endothelial Cells
- 2001 - 2002 Exploration of blood flow-sensing molecules in vascular endothelial cells
- 1999 - 2002 単一細胞機能評価の新手法
- 1999 - 2002 Supervision of the Research of Single-cell Molecular Technology
- 2001 - 2001 生体分子・細胞の力学応答と組織再構築のマイクロバイオメカニクス
- 2001 - 2001 「脳の形成」と「生活習慣病予防」に運動が必要なわけを探る-個体の運動解析モデルと細胞による運動解析モデルの開発-
- 1999 - 2000 DEVELOPMENT OF INTRAVITAL LASER MICROSCOPE FOR VISUALIZATION OF MICROVASCULAR PO_2 DISTRIBUTION
- 1999 - 2000 Elucidation of the mechanism of vascular cell sensing and gene responses to mechanical stresses
- 1998 - 2000 CONTROL OF BIOLOGICAL PROCESSES BY STRONG MAGNETIC FIELDS
- 1997 - 2000 Effects of hemodynamic forces on pulmonary hypertension in congenital heart diseases
- 1997 - 2000 Molecular Mechanism of Atherosclerosis
- 1998 - 1999 Study on Mechanisms of Angiogenesis Induced by Blood Flow using in vivo Experimental Model
- 1997 - 1998 Analysis of Anigogenesis and Shear-Mismatching Response Based on Endothelial Cell Biomechanics
- 1996 - 1998 Cloning of shear stress-sensitive endothelial genes
- 1995 - 1996 CLONING OF MECHANOSENSITIVE RECEPTORS
- 1995 - 1996 A Bio-Engineering Approach to Endothelial Cell Signal Transduction and Responses to Fluid Shear Stress
- 1993 - 1995 A Bio-Engineering Research on the Sensing and Responding Mechanism of Vascular Endothelial Cells to Blood Flow
- 1994 - 1994 メカノトランスダクションの分子機構
- 1994 - 1994 血管内皮・平滑筋細胞の物理的刺激に対する反応に関する生体工学的研究
- 1993 - 1994 DEVELOPMENT OF INTRAVITAL LASER MICROSCOPE FOR THE OBSERVATION OF OXYGEN DISTRIBUTION
- 1991 - 1994 Bio-engineering study on the mechanism of endothelial cell responses to blood flow
- 1993 - 1993 血流と血管内皮・平滑筋細胞の相互作用に関する分子生物学的・生体工学的研究
- 1993 - 1993 血管内皮・平滑筋細胞の物理的刺激に対する反応に関する生体工学的研究
- 1992 - 1992 血流と血管内皮・平滑筋細胞の相互作用に関する分子生物学的・生体工学的研究
- 1990 - 1992 培養血管内皮細胞の老化に関する分子生物学的・生体工学的解析
- 1990 - 1992 A study on Non-invasive Multifunctional Measurements of Circulatry Parameters Using Bio-electrical and Photo-plethysmography Techniques
- 1991 - 1991 血流と血管内皮・平滑筋細胞の相互作用に関する分子生物学的・生体工学的研究
- 1989 - 1990 Development of a New Ambulatory Monitoring System for Indirect Beat-to-Beat Arterial Blood Pressure Using the Volume-compensation Method
- 1989 - 1990 Molecular Biological and Bio-Engineering Study of Blood Flow-Sensing and Responding Mechanism of Vascular Endothelial Cells.
- 1986 - 1987 Development of a new compact centrifugal blood pump system for extracorporeal circulation and its application
- 1985 - 1985 細胞培養法を用いた血管壁細胞に対する血行力学的応力の作用に関する研究
- 細胞組織工学に関する研究
- 動脈硬化の分子機序に関する研究
- Study on cellular tissue engineering
- Study on molecular mechanism for atherogenesis
- Study on vascular cell biomechanics
Show all
Papers (99)：
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山本 希美子, 安藤 譲二. 【血管・リンパ管研究の最前線と治療への展開】血管構築と血管機能・病態 メカノセンシングを介した血管細胞の分化誘導. 医学のあゆみ. 2024. 289. 13. 978-986
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Kimiko Yamamoto, Yuji Shimogonya, Ryohei Maeno, Kenshiroh Kawabe, Joji Ando. Endothelial cells differentially sense laminar and disturbed flows by altering the lipid order of their plasma and mitochondrial membranes. American Journal of Physiology-Cell Physiology. 2023
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Joji Ando, Kimiko Yamamoto. Hemodynamic Forces, Endothelial Mechanotransduction, and Vascular Diseases. Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine. 2022. 21. 2. 258-266
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Kimiko Yamamoto, Yoshitsugu Nogimori, Hiromi Imamura, Joji Ando. Shear stress activates mitochondrial oxidative phosphorylation by reducing plasma membrane cholesterol in vascular endothelial cells. Proceedings of the National Academy of Sciences. 2020. 117. 52. 33660-33667
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安藤 譲二, 山本 希美子. 【MRIで読み解く心臓と脈管:流れと機能】内皮細胞の血流応答異常が血管病変を招く. 臨床画像. 2020. 36. 1. 4-12
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MISC (129)：
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安藤 譲二, 山本 希美子. 生命機能を支えるメカノセンシング 循環系のメカノセンシング. 血管医学. 2016. 17. 3. 315-324
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Shear stress sensing. 2016. 257. 10. 1008-1014
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Kimiko Yamamoto, Joji Ando. Caveolar membrane lipid order affects ATP-mediated shear stress mechanotransduction in vascular endothelial cells. PURINERGIC SIGNALLING. 2014. 10. 4. 801-801
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Y. Suzuki, K. Yamamoto, J. Ando, K. Matsumoto, T. Matsuda. Arterial shear stress accelerates the differentiation of endothelial progenitor cells adhered on VEGF-bound surface. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. 2012. 6. 241-241
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Yamamoto Kimiko, ANDO Joji. 8F15 Endothelial mechanotransduction of shear stress and its role in he control of vascular functions. 2012. 2012. 24. "8F15-1"-"8F15-2"
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Books (4)：
-
Flow-induced endothelial gene regulation
In"Mechanical Forces and the Endothelium", Harwood Academic Publishers, London 1999
-
Flow-induced endothelial gene regulation
Mechanical Forces and the Endothelium 1999
-
シェアストレスと内皮細胞
メディカルレビュー社 1996
-
Shear Stress and Vascular Endothelial Cells
Medical Review Company 1996
Professional career (1)：
- Medical Doctor (Hokkaido University)
Work history (1)：
- 2009 - 現在 Dokkyo Medical University School of Medicine, School of Medicine
Committee career (5)：
- 2015 - 日本バイオレオロジー学会 名誉顧問
- 2015 - 日本微小循環学会 評議員
- 2014 - 日本脈管学会 特別会員
- 1999 - 日本血管細胞生物学会 名誉会員
- 1995 - 日本エム・イー学会 名誉会員
Awards (1)：
Association Membership(s) (8)：
日本バイオレオロジー学会
, 日本内科学会
, 米国生理学会
, 日本脈管学会
, 日本微小循環学会
, 日本血管細胞生物学会
, 日本循環器学会
, 日本エム・イー学会
