Rchr
J-GLOBAL ID：200901074062966132   Update date: Nov. 20, 2024

Maruyama Reo

Maruyama Reo
Affiliation and department：
Japanese Foundation for Cancer Research Department of Cancer Epigenomics, Cancer Institute

About Japanese Foundation for Cancer Research Department of Cancer Epigenomics, Cancer Institute


Job title： Director
Other affiliations (1)：
  • Japanese Foundation for Cancer Research  NEXT-Ganken Program   Associate Program Director
Homepage URL  (1)： https://r-maruyama-lab.github.io/index.html
Research field  (3)： Tumor biology ,  Molecular biology ,  Tumor diagnostics and therapeutics
Research keywords  (9)： cancer bioloty ,  tumor heterogeneity ,  intra-tumor heterogeneity ,  phenotypic plasticity ,  epigenetics ,  bioinformatics ,  ecDNA ,  epigenetic modifiers ,  reverse translational research
Research theme for competitive and other funds  (42)：
  • 2024 - 2029 Regulation of genome by hydrogel: Spatial analysis of reprogramming of cancer stem cells towards development of therapeutic drugs
  • 2024 - 2027 がんの転移・再発過程で生じる細胞リプログラミング機構の解明
  • 2024 - 2027 Elucidation of Drug Resistance Mechanisms Through Longitudinal Transcriptomic Analysis of Circulating Tumor Cells
  • 2024 - 2027 染色体外DNAの分配ダイナミクスに影響を与える分子の同定
  • 2024 - 2027 腫瘍内不均一性の形成過程における染色体外DNAの果たす役割の解明
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Papers (116)：
  • Yuri Sakimoto, Kohei Kumegawa, Shimpei Matsui, Tomohiro Yamaguchi, Toshiki Mukai, Koji Okabayashi, Seiichi Mori, Yuko Kitagawa, Takashi Akiyoshi, Reo Maruyama. Single-cell RNA-seq analysis of cancer-endothelial cell interactions in primary tumor and peritoneal metastasis from a single patient with colorectal cancer. BJC reports. 2024. 2. 1. 88-88
  • Kazutaka Otsuji, Yoko Takahashi, Tomo Osako, Takayuki Kobayashi, Toshimi Takano, Sumito Saeki, Liying Yang, Satoko Baba, Kohei Kumegawa, Hiromu Suzuki, et al. Serial single-cell RNA sequencing unveils drug resistance and metastatic traits in stage IV breast cancer. NPJ precision oncology. 2024. 8. 1. 222-222
  • Ryo Shiraishi, Gabriele Cancila, Kohei Kumegawa, Jacob Torrejon, Irene Basili, Flavia Bernardi, Patricia Benites Goncalves da Silva, Wanchen Wang, Owen Chapman, Liying Yang, et al. Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression. Developmental Cell. 2024
  • Osamu Gotoh, Yuko Sugiyama, Akiko Tonooka, Mayuko Kosugi, Sunao Kitaura, Ryu Minegishi, Masatoshi Sano, Sayuri Amino, Rie Furuya, Norio Tanaka, et al. Genetic and epigenetic alterations in precursor lesions of endometrial endometrioid carcinoma. The Journal of pathology. 2024
  • Liying Yang, Kohei Kumegawa, Sumito Saeki, Tomoyoshi Nakadai, Reo Maruyama. Identification of lineage-specific epigenetic regulators FOXA1 and GRHL2 through chromatin accessibility profiling in breast cancer cell lines. Cancer Gene Therapy. 2024
ｍore...
MISC (149)：
  • Ryo Shiraishi, Gabriele Cancila, Kohei Kumegawa, Patricia da Silva, Owen Chapman, Wang Wanchen, Maki Jami, Mikio Hoshino, Stefan Pfister, Lukas Chavez, et al. DYNAMIC CHROMATIN ALTERATION INDUCES ONCOGENIC HIJACKING BY ESSENTIAL TRANSCRIPTIONAL FACTORS DURING SHH MEDULLOBLASTOMA TUMORIGENESIS. NEURO-ONCOLOGY. 2022. 24. 107-108
  • 目澤 義弘, 醍醐 弥太郎, 高野 淳, 宮城 洋平, 横瀬 智之, 山下 年成, 丸山 玲緒, 清宮 啓之, 折茂 彰. グローバルなヒストン脱アセチル化は癌関連線維芽細胞の筋線維芽細胞性に必須である. 日本癌学会総会記事. 2021. 80回. [J11-1]
  • Yu Koyama, Yoshihiro Mezawa, Yasuhiko Ito, Takumi Koyama, Yataro Daigo, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Keisuke Sugahara, et al. RUNX3 expression plays tumor-suppressive roles by inhibiting the inflammatory trait in human breast CAFs. CANCER SCIENCE. 2021. 112. 749-749
  • Yoshihiro Mezawa, Yataro Daigo, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Reo Maruyama, Hiroyuki Seimiya, Akira Orimo. Global histone deacetylation is a novel epigenetic alteration in tumor-promoting carcinoma-associated fibroblasts. CANCER SCIENCE. 2021. 112. 675-675
  • Ryo Shiraishi, Mana Shimoda, Reo Maruyama, Daisuke Kawauchi. Analysis of epigenetic alteration required for malignant transformation of pre-neoplastic cells in a brain tumor. CANCER SCIENCE. 2021. 112. 849-849
ｍore...
Education (2)：
  • - 2007 Sapporo Medical University
  • - 2002 Sapporo Medical University School of Medicine
Professional career (1)：
  • Ph.D. (Sapporo Medical University)
Work history (12)：
  • 2024/11 - 現在 Cancer Institute, Japanese Foundation for Cancer Research Department of Cancer Epigenomics Director
  • 2023/04 - 現在 横浜市立大学大学院医学研究科 客員准教授(兼任)
  • 2022/04 - 現在 東京医科歯科大学大学院医歯学総合研究科 連携教授(兼任)
  • 2021/04 - 現在 名古屋市立大学大学院薬学研究科 客員教授(兼任)
  • 2020/04 - 現在 Japanese Foundation for Cancer Research NEXT-Ganken Program Associate Program Director
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Committee career (4)：
  • 2022 - 現在 先端モデル動物支援プラットフォーム(AdAMS) 若手支援技術講習会・アドバイザー(2022年〜)
  • 2022 - 現在 日本乳癌学会 評議員(2022年〜)、学術総会プログラム委員(2022年)
  • 2021 - 現在 日本癌学会 評議員(2021年〜)
  • 2020 - 2024 JBCRG (Japan Breast Cancer Research Group) アドバイザリーボード委員会(2020年〜2024年)
Awards (3)：
  • 2015 - 第35回日本分子腫瘍マーカー研究会 学術奨励賞
  • 2010/01 - Scholar-in-training awards (AACR Special Conference on Cancer Epigenetics)
  • 2010 - Scholar-in-training awards (AACR Special Conference on Cancer Epigenetics)
Association Membership(s) (5)：
米国癌学会 ,  日本内科学会 ,  日本分子生物学会 ,  日本癌学会 ,  日本乳癌学会
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