Rchr
J-GLOBAL ID:200901074270994913
Update date: Dec. 18, 2024
Hatano Etsuro
ハタノ エツロウ | Hatano Etsuro
Affiliation and department:
Job title:
Professor
Research field (3):
Digestive surgery
, General surgery, pediatric surgery
, Medical biochemistry
Research keywords (9):
multidisciplinary treatment
, navigation for surgery
, less invasive surgery
, アポトーシス
, 胆道癌
, 肝細胞癌
, Apoptosis
, Biliary cancer
, Hepatocellular carcinoma
Research theme for competitive and other funds (44):
- 2024 - 2028 マウス脂肪肝移植を用いた代謝免疫学的アプローチによる肝虚血再灌流障害の機序解明
- 2023 - 2028 切除不能な肝門部領域胆管癌に対する生体肝移植で治癒に至る分子生物学的特性の解明
- 2024 - 2027 腹腔内脂肪分解抑制による術後膵液瘻重症化予防法の確立
- 2024 - 2027 新規治療法を目指した細胆管細胞癌の臨床病理学解析およびゲノム解析による統合解析
- 2024 - 2027 肝切除後門脈血流刺激に対する内皮細胞応答の解析と肝線維化に伴う内皮機能障害の修復
- 2023 - 2026 Precise liver gene theraphy based on individual HO-1 morphism with normothermic machine perfusion
- 2022 - 2025 The establishment of biliary drainage system in bio-engineered liver
- 2022 - 2025 非感染性炎症における新たな自然免疫細胞制御機構の探求
- 2022 - 2025 胆道癌の腫瘍内不均一性を基盤とした新規治療標的の開発
- 2021 - 2024 Analysis of molecular mechanisum of pancreatic cancer cell death and immune responce after carbon ion radiiation and its application to surgery
- 2021 - 2024 超音波レオロジー理論を用いた脂肪性肝障害の病態解明と非侵襲的組織診断法の確立
- 2021 - 2024 Development of a Next Generation Surgical Navigation System Using Vascular Visualization Technology
- 2021 - 2024 Development of digital evaluation system of gastric conduit blood flow using ICG fluorescence imaging projection
- 2020 - 2023 Role of hepato-splenic interaction in portal hypertension
- 2019 - 2022 マイクロバブルを用いた血流解析による、転移性肝癌viability評価方法の確立
- 2019 - 2022 Functional analysis of IL-11 in chalangiocarcinoma and its clinical application
- 2018 - 2021 Molecular mechanisms of regulation of abdominal adhesion formation by anti-IL-6 antibody.
- 2016 - 2019 Elucidation of pathophysiology of chemotherapy-induced liver injury by pig proteomics and development of diagnostic biomarkers
- 2016 - 2019 Imaging Mass Spectrometry of Liver Regeneration
- 2015 - 2017 Regulation of metabolism and inflammation through hepatic vagus nerve system in steatohepatitis
- 2012 - 2015 Identification of risk factors of hepatocarcinogenesis in fatty liver disease through the comprehensive analysis of epigenetic alterations
- 2012 - 2014 Establishment of risk assessment for liver resection by liver stiffness measurement with acoustic radio force impulse (ARFI)
- 2011 - 2014 Control of liver fibrosis after transplantation by immunomodulation
- 2010 - 2012 Construction of administration algorithm of novel oral molecular-targeted anti-cancer drugs based on the clarificationof interindividual differences of pharmacokinetics and pharmacodynamics
- 2008 - 2010 Establishment of a new method of inducing differentiation from human embryonic stem cells to hepatocytes in vitro and investigation of the clinical utility for cell transplantation.
- 2008 - 2010 Modification of endoplasmic reticulum stress expands surgical indication in hepatocellular carcinom a
- 2003 - 2010 Clinical randomized study for establishment of standard therapy for hepatocellular carcinoma
- 2007 - 2007 新規抗癌剤による肝障害予防対策-転移性肝癌に対する安全な拡大肝切除のために-
- 2006 - 2007 Establishment of hepatocyte differentiation from human embryonic stem cells in the realizaion of cell transplantation therapy for liver disease.
- 2006 - 2007 腫瘍血管新生と低酸素環境を標的としたテーラーメード癌治療法の創出
- 2006 - 2007 The role of intermediateted filament proteins in hepatic stellate cells in the development of liver fibrosis and hepatocellular carcinoma
- 2006 - 2007 Establishment of the maintenance for hepatic stem/progenitor cells with undifferentiated state using mesenchymal cells
- 2004 - 2006 The development of new radiofrequency device and its clinical application
- 2005 - 2005 「がん抑抑遺伝子」Sept4遺伝子破壊マウスの解析
- 2005 - 2005 肝線維化と肝再生におけるアポトーシス関連遺伝子Septin4の機能解析
- 2004 - 2005 Improvement of perioperative and postoperative management after hepatic resection for HCC by the regulation of hepatic stellate cells.
- 2003 - 2004 Contribution to the extended hepatectomy by the modulation of endoplasmic reticulum stress-induced cell death
- 2003 - 2004 ROCK/Rhoシグナル伝達系制御による肝虚血再潅流障害抑制の新しい治療戦略
- 2000 - 2004 肝臓外科におけるアポトーシスの役割
- 2000 - 2004 The role of apoptosis in liver surgery
- 2002 - 2003 Resarch on trial to suppress surgical in cirrhotic liver by modulating activation of hepatic sinusoidal cells.
- 肝細胞癌標準治療確立のための多施設共同臨床試験
- 生体内アポトーシスの検出法の開発
- Development of in vivo detection of apoptosis
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Papers (839):
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Hiroshi Imaoka, Keita Sasaki, Ryunosuke Machida, Hiroaki Nagano, Sohei Satoi, Masafumi Ikeda, Satoshi Kobayashi, Taro Yamashita, Takuji Okusaka, Akio Ido, et al. Current status of the cost burden of first-line systemic treatment for patients with advanced hepatocellular carcinoma in Japan, 2021-22. Japanese journal of clinical oncology. 2024. 54. 10. 1071-1077
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Masako Mishima, Atsushi Takai, Haruhiko Takeda, Eriko Iguchi, Shigeharu Nakano, Yosuke Fujii, Masayuki Ueno, Takahiko Ito, Mari Teramura, Yuji Eso, et al. TERT upregulation promotes cell proliferation via degradation of p21 and increases carcinogenic potential. The Journal of pathology. 2024
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Ikuo Nakamura, Tomoaki Yoh, Takashi Nishimura, Masayuki Okuno, Tomohiro Okamoto, Hideaki Sueoka, Kenjiro Iida, Masaharu Tada, Takamichi Ishii, Satoru Seo, et al. A classification model for resectability in hepatocellular carcinoma patients. Hepatology Research. 2024
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Hiroshi Horie, Yu Oshima, Ken Fukumitsu, Kentaro Iwaki, Fumiaki Munekage, Kenta Makino, Satoshi Wakama, Takashi Ito, Katsuhiro Tomofuji, Satoshi Ogiso, et al. Antithrombotic Revascularization Strategy of Bioengineered Liver Using a Biomimetic Polymer. Tissue engineering. Part A. 2024
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Masayuki Ueno, Haruhiko Takeda, Atsushi Takai, Hiroki Morimura, Norihiro Nishijima, Satoru Iwamoto, Shunsuke Okuyama, Makoto Umeda, Takeshi Seta, Atsuyuki Ikeda, et al. CRAFITY score as a predictive marker for refractoriness to atezolizumab plus bevacizumab therapy in hepatocellular carcinoma: a multicenter retrospective study. Journal of gastroenterology. 2024
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MISC (578):
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椚谷 健, 小木曾 聡, 楊 知明, 白井 久也, 奥村 晋也, 平尾 浩史, 藤本 正数, 吉田 朗彦, 波多野 悦朗. 後腹膜に発生した悪性髄膜腫の1例. 日本消化器病学会近畿支部例会プログラム・抄録集. 2023. 119回. 85-85
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Takahiro Nishio, Kojiro Taura, Yukinori Koyama, Takamichi Ishii, Etsuro Hatano. Current status of preoperative risk assessment for posthepatectomy liver failure in patients with hepatocellular carcinoma. ANNALS OF GASTROENTEROLOGICAL SURGERY. 2023
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鳥口寛, 鳥口寛, 波多野悦朗, 多田正晴, 北村好史, 中村育夫, 奥野将之, 岡本共弘, 末岡英明, 飯田健二郎, et al. 肝細胞癌のタンパク質リン酸化プロファイルの多様性に基づくprecision medicineへの可能性の探求. 肝臓. 2023. 64. Supplement 1
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内田洋一朗, 飯島尋子, 飯島尋子, 東浦晶子, 柴田陽子, 石井隆道, 西村貴士, 西村貴士, 廣田誠一, 隈部力, et al. A case of liver tumor increased in size. 超音波医学 Supplement. 2023. 50
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Kazuyuki Nagai, Toshihiko Masui, Takayuki Anazawa, Kei Yamane, Yosuke Kasai, Yoichiro Uchida, Takashi Ito, Takamichi Ishii, Etsuro Hatano. ASO Author Reflections: Preoperative Endoscopic Minor Papilla Sphincterotomy May Effectively Prevent Pancreatic Fistula After Distal Pancreatectomy in Patients with Pancreas Divisum. Annals of Surgical Oncology. 2023
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Works (2):
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肝アポトーシスにおけるSept4の役割
2004 - 2006
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The role of Sept4 in liver apoptosis
2004 - 2006
Education (4):
- - 1997 Kyoto University
- - 1997 Kyoto University Graduate School of Medicine Gastroenterological Surgery
- - 1989 Kyoto University Faculty of Medicine Department of Medical Science
- - 1989 Kyoto University Faculty of Medicine
Professional career (1):
- Degree of Medicine (Kyoto University)
Work history (7):
- 2021/04 - 現在 Graduate School of Medicine, Kyoto University Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery Professor
- 2019/12 - 2021/09 Hyogo College of Medicine Professor and Chairman
- 1998 - 2000 Research Fellow,
- 1997 - 1998 Research Associate,
- the Japan Society for the Promotion of Science
- Graduate School of Medicine
- Kyoto University,
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Association Membership(s) (17):
日本癌治療学会
, 日本内視鏡外科学会
, 日本臨床外科学会
, 日本肝臓学会
, 日本消化器病学会
, 日本外科学会
, The Japanese Society of Gastroenterological Surgery
, Liver Cancer Study Group of Japan
, 日本肝移植学会
, 日本超音波学会
, 日本臨床腫瘍学会
, 日本外科感染症学会
, 日本門脈圧亢進症学会
, 日本膵臓学会
, 日本胆道学会
, 日本移植学会
, 日本肝胆膵外科学会
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