Rchr
J-GLOBAL ID:200901074643628572   Update date: May. 08, 2023

INOSE-MARUYAMA ATSUSHI

イノセ(マルヤマ) アツシ | INOSE-MARUYAMA ATSUSHI
Affiliation and department:
Job title: Associate Professor
Research field  (3): Pharmaceuticals - health and biochemistry ,  Medical biochemistry ,  Bacteriology
Research keywords  (3): oxidative stress ,  Molecular Biology ,  Bacteriology
Research theme for competitive and other funds  (7):
  • 2015 - 2017 エンハンサーRNAが制御するヒトヘムオキシゲナーゼ-1遺伝子発現増強機構の解明
  • 2013 - 2014 エンハンサー由来lncRNAによるNrf2依存的HO-1遺伝子発現増強機構の解明
  • 2011 - 2012 Nrf2依存的遺伝子発現活性化におけるZ-DNA構造の機能解明
  • 2008 - 2012 活性酸素のシグナル伝達機能
  • 2006 - 2006 Nrf2活性化に基づく神経変性疾患予防剤評価法の開発
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Papers (37):
  • Atsushi Inose-Maruyama, Shuya Kasai, Ken Itoh. Human Heme Oxygenase-1 Promoter Activity Is Mediated by Z-DNA Formation. Methods in molecular biology (Clifton, N.J.). 2023. 2651. 157-166
  • Hayato Irokawa, Satoshi Numasaki, Shin Kato, Kenta Iwai, Atsushi Inose-Maruyama, Takumi Ohdate, Gi-Wook Hwang, Takashi Toyama, Toshihiko Watanabe, Shusuke Kuge. Comprehensive analyses of the cysteine thiol oxidation of PKM2 reveal the effects of multiple oxidation on cellular oxidative stress response. The Biochemical journal. 2021. 478. 7. 1453-1470
  • Hiromi Yamazaki, Shuya Kasai, Junsei Mimura, Peng Ye, Atsushi Inose-Maruyama, Kunikazu Tanji, Koichi Wakabayashi, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, et al. Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice. PLoS genetics. 2020. 16. 4. e1008693
  • Junsei Mimura, Atsushi Inose-Maruyama, Shusuke Taniuchi, Kunio Kosaka, Hidemi Yoshida, Hiromi Yamazaki, Shuya Kasai, Nobuhiko Harada, Randal J Kaufman, Seiichi Oyadomari, et al. Concomitant Nrf2- and ATF4-activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes. International journal of molecular sciences. 2019. 20. 7
  • Kunikazu Tanji, Yasuo Miki, Atsushi Maruyama, Fumiaki Mori, Junsei Mimura, Ken Itoh, Tetsu Kamitani, Koichi Wakabayashi. The role of NUB1 in alpha-synuclein degradation in Lewy body disease model mice. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2016. 470. 3. 635-642
more...
MISC (4):
  • Mitsuru Chiba, Narumi Watanabe, Miki Watanabe, Maki Sakamoto, Akika Sato, Mizuki Fujisaki, Shiori Kubota, Satoru Monzen, Atsushi Maruyama, Naoki Nanashima, et al. Exosomes derived from SW480 colorectal cancer cells promote cell migration in HepG2 hepatocellular cancer cells via the mitogen-activated protein kinase pathway. International journal of oncology. 2016. 48. 1. 305-12
  • Ken Itoh, Nobuhiko Harada, Masaya Kanayama, Atsushi Maruyama, Aruto Yoshida, Masayuki Yamamoto. Nitric oxide responsive transcription factor Nrf2 regulates Fpn1-mediated iron efflux and counteracts the inflammation-mediated Fpn1 mRNA suppression. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2010. 22. S56-S56
  • T Hosoya, A Maruyama, MI Kang, Y Kawatani, T Shibata, K Uchida, E Warabi, N Noguchi, K Itoh, M Yamamoto. Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells. (vol 280, pg 27244, 2005). JOURNAL OF BIOLOGICAL CHEMISTRY. 2005. 280. 33. 29988-29988
  • M Kuroda, T Ohta, Uchiyama, I, T Baba, H Yuzawa, Kobayashi, I, LZ Cui, A Oguchi, K Aoki, Y Nagai, et al. Whole genome sequencing of meticillin-resistant Staphylococcus aureus. LANCET. 2001. 357. 9264. 1225-1240
Books (3):
  • 実験医学 増刊、活性酸素・ガス状分子による恒常性制御と疾患
    羊土社 2012
  • 分子細胞治療
    2006
  • 医学のあゆみ別冊,レドックス-ストレス防御の医学
    医歯薬出版株式会社 2005
Lectures and oral presentations  (5):
  • 活性酸素種センサータンパク質BAG-1によるeIF2aリン酸化レベル制御の解析
    (フォーラム2017 衛生薬学・環境トキシコロジー 2017)
  • 細胞内Z-DNA構造形成を測る-DNA構造変化の遺伝子発現制御における役割-
    (日本化学会東北支部 平成27年度化学系学協会東北大会 2015)
  • Nrf2依存的なヒトHO-1遺伝子発現活性化機構の解析
    (第77回日本生化学会 東北支部例会 2011)
  • 原子間力顕微鏡(AFM)による細菌分子のイメージング
    (第59回日本顕微鏡 学会学術講演大会 2003)
  • S.aureusの酸化ストレス応答遺伝子qorの解析
    (第49回ブドウ球菌研究会 2000)
Education (4):
  • - 2004 University of Tsukuba
  • 2001 - 2004 University of Tsukuba
  • 1999 - 2001 University of Tsukuba Graduate School, Master's Course, Division of Medical Science
  • 1995 - 1999 Ehime University Faculty of Science Department of Biology
Professional career (1):
  • (BLANK) (University of Tsukuba)
Work history (4):
  • 2019/04 - 現在 Nihon Pharmaceutical University Division of Microbiology and Molecular Cell Biology
  • 2016/04 - 2019/03 Tohoku Medical and Pharmaceutical University
  • 2006/03 - 2016/03 Hirosaki University Graduate School of Medicine
  • 2004/05 - 2006/03 JST ERATO Yamamoto Enviromental Response Project
Association Membership(s) (5):
THE PHARMACEUTICAL SOCIETY OF JAPAN ,  SOCIETY FOR FREE RADICAL RESEARCH JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  Japanese Society for Bacteriology ,  The Molecular Biology Society of Japan
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