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J-GLOBAL ID：200901074792652672   Update date: Sep. 10, 2024

Tsutsui Hiroko

ツツイ ヒロコ | Tsutsui Hiroko
Affiliation and department：
Hyogo College of Medicine Faculty of Medicine

About Hyogo College of Medicine Faculty of Medicine


Job title： Professor
Research field  (4)： Allergies and connective tissue disease ,  Gastroenterology ,  Immunology ,  Bacteriology
Research keywords  (8)： Fulminant hepatitis ,  Atopic diseases ,  Interleukin 1 family ,  Host response to bacterial infection ,  Caspases ,  IL-18 ,  IL-33 ,  Activation of caspase-1
Research theme for competitive and other funds  (52)：
  • 2021 - 2024 Analysis of molecular mechanisum of pancreatic cancer cell death and immune responce after carbon ion radiiation and its application to surgery
  • 2018 - 2021 Molecular mechanisms of regulation of abdominal adhesion formation by anti-IL-6 antibody.
  • 2014 - 2017 Mechanism of Fas-mediated inflammatory response against bacterial infection in vivo
  • 2014 - 2016 Dermatitis and activation of IL-33
  • 2013 - 2016 慢性間疾患における肝細胞障害と肝内凝固亢進状態の関連性に関する検討
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Papers (233)：
  • Makoto Sudo, Hiroko Tsutsui, Shuhei Hayashi, Koubun Yasuda, Keiko Mitani, Nana Iwami, Makoto Anzai, Toshiro Tsubouchi, Mitsuaki Ishida, Sohei Satoi, et al. Autophagy Inhibition Increased Sensitivity of Pancreatic Cancer Cells to Carbon Ion Radiotherapy. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2023. 57. 4. 212-225
  • Makoto Sudo, Jinyang Xu, Keiko Mitani, Mayo Jimbo, Hiroko Tsutsui, Etsuro Hatano, Jiro Fujimoto. Antithrombin together with NETs inhibitor protected against Postoperative adhesion formation in mice. Cellular Physiology and Biochemistry. 2021. 55. 4. 400-412
  • Makoto Sudo, Kenjiro Iida, Hiroko Tsutsui, Keiko Mitani, Mayo Jimbo, Etsuro Hatano, Jiro Fujimoto. Blockade of tumor necrosis factor by etanercept prevents postoperative adhesion formation in mice. Cellular Physiology and Biochemistry. 2020. 54. 5. 1041-1053
  • Naoki Uyama, Hiroko Tsutsui, Songtao Wu, Koubun Yasuda, Etsuro Hatano, Xian-Yang Qin, Soichi Kojima, Jiro Fujimoto. Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation. Scientific reports. 2019. 9. 1. 17558-17558
  • Rendong Fang, Ryosuke Uchiyama, Shunsuke Sakai, Hideki Hara, Hiroko Tsutsui, Takashi Suda, Masao Mitsuyama, Ikuo Kawamura, Kohsuke Tsuchiya. ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism. Mucosal Immunology. 2019. 12. 5. 1092-1103
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MISC (221)：
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Books (25)：
  • 宿主と病原体の攻防
    ”コア免疫学第2版”(木本雅夫、阪口薫雄、山本優毅 編集)南山堂 2007
  • Interleukin-18 [IL-1F4]
    Elsevier Science Ltd 2003
  • IL-18 and IL-18 receptor knockout mice in "Cytokine Knockouts 2nd Edition"
    Humana Press Inc. Ttowa NJ 2003
  • Interleukin-18 in "Encyclopedia of Hormones"
    Academic Press 2003
  • 自己免疫
    "免疫学コア講義 " 南山堂 2002
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Works (6)：
  • シグナル抑制因子SOCS-1の欠除に基く肝障害の発症機構の解析
    1998 -
  • Molecularmechanisms of severe hepatitis in SOCS-1-deficient mice
    1998 -
  • caspase-1欠損マウスにみられるListeria monocytogenesの排菌異常
    1997 -
  • IL-18過剰発現によるアトピー性ヒフ炎の誘導
    1997 -
  • Impairment of listerial clearance in caspase-1-deficient mice
    1997 -
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Education (2)：
  • - 1985 Osaka City University Medical School
  • - 1981 Osaka City University Medical School
Professional career (1)：
  • Medical Doctor (Osaka City University)
Work history (8)：
  • 2016/04 - 現在 Hyogo Medical University
  • 2006/01 - 2015/03 Hyogo Medical University
  • 2000/01 - 2005/12 Hyogo Medical University Associated Professor
  • 1996 - 2000 Hyogo College of Medicine
  • 2000 - - 兵庫医科大学 助教授
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Committee career (2)：
  • 2008 - 現在 日本細菌学会 評議員
  • 日本免疫学会評議員
Association Membership(s) (10)：
日本感染症学会 ,  日本ウイルス学会 ,  日本細菌学会 ,  日本生化学会 ,  日本肝臓学会 ,  日本免疫学会 ,  Japanese Society for Virology ,  Japanese Society of Liver Diseases ,  Japanese Society for Bacterology ,  Japanese Society for Immunoloty
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