Yanokura Megumi

ヤノクラメグミ | Yanokura Megumi

Affiliation and department：
Job title： Project Assistant Professor (Non-tenured)/Project Research Associate (Non-tenured)/Project Instructor (Non-tenured)

Research field (1)： Obstetrics and gynecology

Research keywords (4)：薬剤感受性 , 細胞周期チェックポイント , 子宮体癌 , DNAメチル化

Research theme for competitive and other funds (7)：

2022 - 2025 Elucidation of implantation inhibition mechanism of endometrial cancer cells using iPS technology
2018 - 2021 Reprogramming study of endometrial cancer cells for restoring fertility
2015 - 2018 Genome-wide DNA methylation analysis in endometrial cancer
2012 - 2015 Application to the development and diagnosis of miRNA therapeutic agent in endometrial cancer
2010 - 2012 endometrial cancer therapy using epigenetically regulated small RNA

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Papers (112)：

矢野倉恵, 阪埜浩司, 的場優介, 小林佑介, 冨永英一郎, 田中守, 青木大輔. リプログラミングされた子宮体癌由来培養細胞を用いた内膜着床阻止メカニズムの探索. 日本産科婦人科学会雑誌. 2021. 73. 臨増. S-316
Megumi Yanokura, Kouji Banno, Daisuke Aoki. MicroRNA-34b expression enhances chemosensitivity of endometrial cancer cells to paclitaxel. International Journal of Oncology. 2020. 57. 5. 1145-1156
Umene K, Banno K, Kisu I, Yanokura M, Nogami Y, Tsuji K, Masuda K, Ueki A, Kobayashi Y, Yamagami W, et al. Erratum: Aurora kinase inhibitors: Potential molecular-targeted drugs for gynecologic malignant tumors (Review). Biomedical reports. 2019. 11. 6. 274-274
Takeda T, Banno K, Kobayashi Y, Adachi M, Yanokura M, Tominaga E, Kosaki K, Aoki D. Mutations of RAS genes in endometrial polyps. Oncology Reports. 2019. 42. 6. 2303-2308
Matoba Y, Kisu I, Sera A, Yanokura M, Banno K, Aoki D. Current status of uterine regenerative medicine for absolute uterine factor infertility (Review). Biomedical Reports. 2019. 10. 2. 79-86

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MISC (23)：

矢野倉恵, 阪埜浩司, 的場優介, 辻浩介, 小林佑介, 冨永英一郎, 田中守, 青木大輔. ヒト子宮体癌由来培養細胞を用いたReprogrammed-Cancer cellの作成. 日本産科婦人科学会雑誌. 2019. 71. 臨増. S-504
AOKI DAISUKE. 子宮内膜癌(類内膜癌)のゲノム解析. 日本臨床婦人科がん(第2版)-最新の研究動向-. 2018. 76. 増刊号2. 384-389
Kunitomi Haruko, Kobayashi Yusuke, Banno Kouji, Okawa Ryuichiro, Masuda Kenta, Yanokura Megumi, Tominaga Eiichiro, Tanaka Mamoru, Aoki Daisuke. ISP-8-4 The characteristics of LAMC1 expression patterns associated with the clinical features of endometrial cancer(Group 8 Endometrial Cancer 3,International Session Poster) :. 2016. 68. 2. 500-500
大川隆一朗, 阪埜浩司, 矢野倉恵, 増田健太, 安達将隆, 野上侑哉, 國富晴子, 冨永英一郎, 田中守, 青木大輔. P2-5-6 子宮体部明細胞癌に対するARID1Aタンパクの発現解析 : 卵巣明細胞癌との比較(Group5 子宮体部腫瘍・基礎,一般演題,公益社団法人日本産科婦人科学会第68回学術講演会). 日本産科婦人科學會雜誌. 2016. 68. 2. 631-631
Takeda Takashi, Banno Kouji, Yanokura Megumi, Iijima Moito, Iida Miho, Adachi Masataka, Masuda Kenta, Kobayashi Yusuke, Tominaga Eiichiro, Tanaka Mamoru, et al. IS-AC-2-1 Methylation analysis of DNA mismatch repair genes using DNA derived from peripheral blood of patients with endometrial cancer : epimutation in endometrial carcinogenesis(Group 2 Oncology 2,International Session Award Candidate) :. 2016. 68. 2. 457-457

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Lectures and oral presentations (58)：

ヒト子宮体癌由来培養細胞を用いたReprogrammed-Cancer cellの作成
(日本産科婦人科学会雑誌 2019)
【婦人科がん(第2版)-最新の研究動向-】子宮体がん子宮体癌の発生子宮内膜癌(類内膜癌)のゲノム解析
(日本臨床 2018)
CIMP-H子宮体癌患者の末梢血を利用したTargeted bisulfite sequencing
(日本癌学会総会記事 2016)
子宮体部明細胞癌に対するARID1Aタンパクの発現解析卵巣明細胞癌との比較
(日本産科婦人科学会雑誌 2016)
メトホルミンとジエノゲストの併用はDNAのメチル化を変化させ子宮体癌細胞の増殖を抑制させる
(日本産科婦人科学会雑誌 2015)

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Education (2)：

2013 - 2017 筑波大学生命環境科学生物科学
2006 - Keio University Graduate School, Division of Medicine 医科学

Professional career (2)：

修士(医科学) (Keio University)
博士(理学) (筑波大学大学院)

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