Toyama Tatsuya

トオヤマタツヤ | Toyama Tatsuya

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.med.nagoya-cu.ac.jp/mammal.dir/index.html

Research field (1)： General surgery, pediatric surgery

Research keywords (1)：乳癌

Research theme for competitive and other funds (27)：

2023 - 2027 Innovative smartphone psychotherapy targeting both fear of recurrence and persistent chronic pain after curative cancer resection
2022 - 2027 致死性疾患の術後遷延痛と再発不安に対する「オンライン集団ACTプログラム」の開発
2022 - 2025 アミノ酸トランスポーターを標的としたホルモン抵抗性乳がんに対する新規治療法の開発
2021 - 2024 ミトコンドリア呼吸調節因子を標的とした乳がんに対する革新的治療法の開発
2019 - 2022 Discovering novel mechanisms of taxane resistance in human breast cancer

2018 - 2021 Research on novel therapeutic methods for breast cancer based on glucose metabolism

2017 - 2020 TP53INP1 gene in estrogen receptor alfa-positive breast cancer patients

2017 - 2019 Investigating roles of regulatory T cells in inducing anti-tumur immunity and developing immunotherapy in head and neck cancer

2016 - 2019 Exome sequencing of human breast cancer tissues resistant to taxanes.

2016 - 2019 The elucidation of the metastasis in bone marrow mechanism in hormonal therapy-resistant breast cancer and development of the new molecular target drug

2015 - 2018 Treatment strategy of breast cancer using micro RNA-1290

2015 - 2018 Diagnostic approach to breast cancer patients based on target metabolomics in saliva

2014 - 2017 Establishment of estrogen receptor positive breast cancer risk model consisting of genetic polymorphisms and serum biomarkers

2013 - 2016 The target therapy for LMTK3 in hormone receptor-positive breast cancer

2012 - 2015 New treatment strategy for triple-negative breast cancer targeting micro RNA

2011 - 2013 Estrogen receptor positive breast cancer risk score constructed by genetic factors and endogenous hormones

2011 - 2012 Analysis of microRNAs and development of novel therapeutic strategies in breast cancer

2010 - 2012 The role of cathepsin E in mammary carcinogenesis and prognosis in breast cancer

2009 - 2011 Estrogen receptor knock down therapy using microRNA for breast cancer patients

2008 - 2010 Development of new biomarkers in breast cancer by glycomic profile analyses

2004 - 2005 乳癌におけるStat5を標的とした分子標的治療および乳癌予防薬開発の可能性の検討

2002 - 2004 Clinicopathological and Functional Analysis of Hormone Related Gene in Breast Cancer

2002 - 2003 The role of co-factor of estrogen receptor alfa in breast cancer cells

2001 - 2002 Analysis of role of Stat5 in breast cancer

2000 - 2001 Analysis of the candidate tumor suppressor ING1 gene in neuroblastoma.

2000 - 2001 乳癌における癌抑制遺伝子候補 ING1 遺伝子の解析

1999 - 2000 Analysis of the Estrogen Receptor α cofactors with reference to Hormone Dependency of Breast Cancer

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Papers (293)：

Maho Kusudo, Mitsuo Terada, Nari Kureyama, Yumi Wanifuchi-Endo, Takashi Fujita, Tomoko Asano, Akiko Kato, Makiko Mori, Nanae Horisawa, Tatsuya Toyama. Characterizing user demographics in posts related to breast, lung and colon cancer on Japanese twitter (X). Scientific reports. 2024. 14. 1. 6485-6485
Tatsuo Akechi, Toshiaki A Furukawa, Hisashi Noma, Hiroji Iwata, Tatsuya Toyama, Kenji Higaki, Hiromichi Matsuoka, Sadamoto Zenda, Tsuguo Iwatani, Kazuhisa Akahane, et al. Optimizing smartphone psychotherapy for depressive symptoms in patients with cancer: Multiphase optimization strategy using a decentralized multicenter randomized clinical trial (J-SUPPORT 2001 Study). Psychiatry and clinical neurosciences. 2024
Mitsuo Terada, Aki Ito, Yuichiro Kikawa, Kei Koizumi, Yoichi Naito, Tatsunori Shimoi, Mikiya Ishihara, Takashi Yamanaka, Yukinori Ozaki, Fumikata Hara, et al. The Japanese Breast Cancer Society Clinical Practice Guidelines for systemic treatment of breast cancer, 2022 edition. Breast cancer (Tokyo, Japan). 2023. 30. 6. 872-884
Nari Kureyama, Mitsuo Terada, Maho Kusudo, Kazuki Nozawa, Yumi Wanifuchi-Endo, Takashi Fujita, Tomoko Asano, Akiko Kato, Makiko Mori, Nanae Horisawa, et al. Fact-Checking Cancer Information on Social Media in Japan: Retrospective Study Using Twitter. JMIR formative research. 2023. 7. e49452
Akiko Kato, Naoto Kondo, Yumi Wanifuchi-Endo, Takashi Fujita, Tomoko Asano, Tomoka Hisada, Yasuaki Uemoto, Mitsuo Terada, Hiroyuki Kato, Masayuki Komura, et al. Low TINAGL1 expression is a marker for poor prognosis in breast cancer. Journal of cancer research and clinical oncology. 2023. 149. 8. 4771-4782

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MISC (87)：

Yutaka Yamamoto, Hiroji Iwata, Taira Naruto, Norikazu Masuda, Masato Takahashi, Tetsuhiro Yoshinami, Takayuki Ueno, Tatsuya Toyama, Takashi Yamanaka, Toshimi Takano, et al. A randomized, open-label, phase III trial of pertuzumab re-treatment in HER2-positive, locally advanced/metastatic breast cancer patients previously treated with pertuzumab, trastuzumab, and chemotherapy: The Japan Breast Cancer Research Group-M05 (PRECIOUS) study. CANCER RESEARCH. 2021. 81. 4
Shinichi Baba, Masataka Sawaki, Yukari Uemura, Tsuyoshi Saito, Kokoro Kobayashi, Hiroaki Kawashima, Michiko Tsuneizumi, Noriko Sagawa, Hiroko Bando, Masato Takahashi, et al. A cohort study to evaluate the efficacy and safety of postoperative adjuvant therapy in HER2-positive elderly breast cancer patients (RESPECT-cohort study). CANCER RESEARCH. 2020. 80. 4
Yuichiro Kikawa, Kentaro Sakamaki, Tomomi Fujisawa, Kazuhiro Araki, Takayuki Iwamoto, Takafumi Sangai, Tadahiko Shien, Shintaro Takao, Reiki Nishimura, Masato Takahashi, et al. HEALTH-RELATED QUALITY OF LIFE IN 2ND-LINE ENDOCRINE THERAPY FOR PATIENTS WITH ACQUIRED ENDOCRINE-RESISTANT POSTMENOPAUSAL ER-POSITIVE, HER2-NEGATIVE METASTATIC BREAST CANCER: THE HORSE-BC STUDY. BREAST. 2019. 48. S72-S73
的場拓磨, 今井優樹, 大倉永也, 川北大介, 伊地知圭, 遠山竜也, 森田明理, 村上信五, 坂口志文, 山崎小百合. 頭頸部癌における制御性T細胞の新たな特徴. 耳鼻咽喉科免疫アレルギー. 2019. 37. 2. 72-73
的場拓磨, 今井優樹, 大倉永也, 川北大介, 伊地知圭, 遠山竜也, 森田明理, 村上信五, 坂口志文, 山崎小百合. 頭頸部癌における制御性T細胞の新たな特徴. 耳鼻咽喉科免疫アレルギー. 2019. 37. 2. 72-73

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Lectures and oral presentations (403)：

Single-Agent Activity of U3-1402, a HER3-Targeting Antibody-Drug Conjugate, in Breast Cancer Patients: Phase 1 Dose Escalation Study.
(The 53th Annual meeting of American Society of Clinical Oncology (ASCO) 2018)
TransNEOS: Validation of the Oncotype DX Recurrence Score testing core needle biopsy samples from NEOS as predictor of clinical response to neoadjuvant endocrine therapy for postmenopausal ER+, HER2-negative breast cancer patients.
(2017 Annual San Antonio Breast Cancer Symposium (San Antonio, U.S.A) 2017)
NEOS: A randomized, open label, phase 3 trial of adjuvant chemotherapy for postmenopausal breast cancer patients who responded to neoadjuvant letrozole: First report of long-term outcome and prognostic value of response to neoadjuvant endocrine therapy.
(2017 Annual San Antonio Breast Cancer Symposium (San Antonio, U.S.A) 2017)
The prognostic impact of Retinoic Acid-Induced 2(RAI2) expression in ERα-positive breast cancer patients.
(2017 Annual San Antonio Breast Cancer Symposium (San Antonio, U.S.A) 2017)
Everolimus (EVE) + letrozole (LET) in patients (pts) with estrogen receptor_positive (ER+), human epidermal growth factor receptor 2_negative (HER2-) advanced breast cancer (ABC): subgroup analysis of first line (1L) progression-free survival (PFS) by rac
(ESMO (European Society for Medical Oncology)-Asia2017 Congress, 2017)

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Education (1)：

1983 - 1989 Nagoya City University Faculty of Medicine

Professional career (1)：

医学博士 (名古屋市立大学医学部)

Work history (8)：

2016/06 - 現在 Nagoya City University Graduate School of Medical Sciences Department of Breast Surgery Professor
2012/10 - 2016/05 Nagoya City University Graduate School of Medical Sciences, Department of Oncology, Immunology and Surgery
2009/10 - 2012/09 Nagoya City University Graduate School of Medical Sciences, Department of Oncology, Immunology and Surgery
2007/04 - 2009/09 Nagoya City University Graduate School of Medical Sciences, Department of Oncology, Immunology and Surgery
2005/10 - 2007/03 Nagoya City University Graduate School of Medical Sciences, Department of Oncology, Immunology and Surgery

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Committee career (6)：

2018 - 現在日本癌治療学会教育委員
2016 - 現在日本乳癌学会診療ガイドライン委員会委員
2016 - 現在日本乳癌学会乳癌診療ガイドライン・薬物療法小委員会委員長
2018 - 2020 日本乳癌学会地方創生委員会 [中部地区]事務局長
2015 - 2020 日本乳癌学会試験問題作成委員会副委員長

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Awards (2)：

2007 - 第45回日本癌治療学会総会優秀演題賞
2000 - 第6回日本乳癌学会研究奨励賞

Association Membership(s) (5)：

日本臨床腫瘍学会 , 日本癌治療学会 , 日本外科学会 , 日本乳癌学会 , 日本癌学会

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