Rchr
J-GLOBAL ID：200901075783647034
Update date: Nov. 11, 2025
Hayakawa Sumio
ハヤカワ スミオ | Hayakawa Sumio
Affiliation and department：
Job title：
Senior Assistant Professor
Homepage URL (1)：
https://www.nms.ac.jp/college.html
Research field (5)：
Cell biology
, Molecular biology
, Medical biochemistry
, Immunology
, Food sciences
Research keywords (2)：
分子生物学、自然免疫、食品栄養科学
, Food and Nutritional Sciences
Research theme for competitive and other funds (16)：
- 2025 - 2028 口腔を起点とした生体防御メカニズムの解明とその応用にむけた基盤研究
- 2024 - 2027 Fundamental Research on the Role of Ketone Bodies and Their Control Methods in Eating Disorders
- 2024 - 2027 茶カテキン酸化物に特異的な生理活性に及ぼす茶飲料中ビタミンCの影響に関する解析
- 2021 - 2025 細胞内コレステロールを基軸とした炎症慢性化の基盤的研究
- 2021 - 2025 細胞内コレステロールを基軸とした炎症慢性化の基盤的研究
- 2020 - 2024 超分子を用いた腫瘍随伴マクロファージのリプログラミングと腫瘍成育微小環境の破壊
- 2016 - 2019 Analysis of lipid metabolism regulation through chronic inflammation
- 2014 - 2017 Activation of innate immune response by DNA from food
- 2013 - 2017 Novel mechanisms of cellular antiviral defense through the PARP-13 shorter isoform, ZAPS
- 2011 - 2013 The study of activation of innate immune response by dietary nucleic acids via oral mucosa
- 2011 - 2012 Analysis of the innate immune response to nucleic acids in tumor cells.
- 2008 - 2009 Basic studies of protective immunity and immune response on catechins.
- 2006 - 2008 Application of oxidation reaction using an assembly of catechol-coppermolecular oxygen toward fine chemistry
- 2006 - 2007 Proteomic a-myofibroblastnalysis of activated- and inactivated
- 2004 - 2006 Research for the medical treatment of organic fibrosis by controlling the protein interacting with connective tissue growth factor
- 2004 - 2006 肺線維化における細胞活化抑制メカニズムの解析
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Papers (43)：
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Azusa Honda, Hiroyuki Koike, Teruyuki Dohi, Eri Toyohara, Sumio Hayakawa, Kazuyuki Tobe, Ichiro Manabe, Rei Ogawa, Yumiko Oishi. CD206+ macrophages facilitate wound healing through interactions with Gpnmbhi fibroblasts. EMBO Reports. 2025
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Asako Narai-Kanayama, Sumio Hayakawa, Takayuki Yoshino, Futa Honda, Hiroko Matsuda, Yumiko Oishi. Differential effects of theasinensins and epigallocatechin-3-O-gallate on phospholipid bilayer structure and liposomal aggregation. Biochimica et biophysica acta. Biomembranes. 2024. 1866. 5. 184312-184312
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Mai Kato, Momoka Yamaguchi, Akira Ooka, Ryota Takahashi, Takuji Suzuki, Keita Onoda, Yuko Yoshikawa, Yuta Tsunematsu, Michio Sato, Yasukiyo Yoshioka, et al. Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice. Scientific reports. 2023. 13. 1. 8924-8924
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Yinglan Cheng, Ichiro Manabe, Sumio Hayakawa, Yusuke Endo, Yumiko Oishi. Caspase-11 contributes to site-1 protease cleavage and SREBP1 activation in the inflammatory response of macrophages. Frontiers in Immunology. 2023. 14
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Anna Nakagawa, Sumio Hayakawa, Yinglan Cheng, Azusa Honda, Ryo Yuzawa, Rei Ogawa, Yumiko Oishi. Cyclic stretch regulates immune responses via tank-binding kinase 1 expression in macrophages. FEBS Open Bio. 2022
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MISC (14)：
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早川清雄, 奈良井朝子, 亀山武志. 茶カテキンによる免疫機能活性化における基盤的研究. 日本栄養・食糧学会大会講演要旨集. 2024. 78th
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新谷雄太郎, 早川清雄, 大倉定之, 田村篤志, 大石由美子, 佐藤卓. Intracellular cholesterol regulation contributes to the anti-HSV-1 activity. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2024. 71st
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安岡璃奈, 銭博聞, 早川清雄, 佐藤卓. 炎症応答におけるマウスNEDD4の機能解析. 日本医科大学医学会雑誌. 2024. 20. 4
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早川清雄, 大石由美子, 大石由美子. 細胞内コレステロールはマクロファージの炎症応答を制御する. New Diet Therapy. 2024. 40. 2
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大山覚照, 大山覚照, 坂井敦, 早川清雄, 内山翔太郎, 内山翔太郎, 荒川亮介, 舘野周, 高岡晃教, 岸泰宏, et al. 神経炎症におけるオレキシンシステムの役割. 総合病院精神医学. 2024. 36. Supplement
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Books (3)：
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Tea, Coffee and Health Benefits Bioactive Molecules in Food
Springer International Publishing AG 2018
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Health benefits of tea consumption, Beverage Impacts on Health and Nutrition
Springer International Publishing, Switzerland 2016
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栄養 評価と治療/緑茶成分によるアポトーシス関連分子の発現調節
メディカルレビュー社 2003
Lectures and oral presentations (23)：
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Cholesterol Accumulation Mediates Inflammation and Promotes HSV-1 Replication: Implications for Atherosclerosis
(18th Asian Pacific Society of Atherosclerosis and Vascular Disease Congress 2025)
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炎症応答に関与するマウスNEDD4の機能的役割の解析
(第93回 日本医科大学医学会総会・学術集会 2025)
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異物を認識する生体防御の最前線・自然免疫応答とそのシグナル経路
(第38回 文京脳腫瘍研究会 2025)
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細胞内コレステロールの制御による抗HSV-1効果の解析
(第71回日本ウイルス学会学術集会 2024)
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Immune Function Activation by Green Tea Catechin
(12th Annual Meeting of the International Cytokine & Interferon Society (ICIS) 2024)
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Education (1)：
- 1999 - 2002 University of Shizuoka Graduate School of Nutritional and Environmental Sciences
Professional career (1)：
- Doctor of Food and Nutritional Sciences (University of Shizuoka)
Work history (6)：
Awards (2)：
- 2017/03 - 東京医科歯科大学 免疫学・病態生化学領域合同シンポジウム 優秀若手研究奨励賞
- 2012/06 - 北海道大学人獣共通感染症リサーチセンター 第1回 人獣共通感染症研究拠点シンポジウム 優秀発表賞
Association Membership(s) (5)：
The Japanese Society for Virology
, The Japanese Society of Clinical Nutrition.
, Japan Society of Nutrition and Food Science
, Japanese Association for Food Immunology
, The Japanese Biochemical Society
