Rchr
J-GLOBAL ID：200901075811337267   Update date: Apr. 12, 2024

Kajimoto Shinji

カジモト シンジ | Kajimoto Shinji
Affiliation and department：
Tohoku University Graduate School of Pharmaceutical Sciences

About Tohoku University Graduate School of Pharmaceutical Sciences


Homepage URL  (2)： https://www.tohoku-biostructchem.com ,  http://db.tohoku.ac.jp/whois/e_detail/73176a7722ea1edebf5017f99fbc7786.html
Research field  (6)： Biophysics ,  Bio-, chemical, and soft-matter physics ,  Molecular biology ,  Structural and functional materials ,  Basic physical chemistry ,  Nanostructure chemistry
Research keywords  (11)： Physical chemistry ,  Biophysical chemistry ,  cell ,  in situ intracellular spectroscopy ,  live cell imaging ,  Raman microscopy ,  laser chemistry ,  nanoparticle synthesis ,  phase separation ,  Raman spectroscopy ,  super-resolution microscopy
Research theme for competitive and other funds  (20)：
  • 2024 - 2027 生細胞内を実験場とした疾患関連タンパク質の相挙動定量解析
  • 2024 - 2025 疾患関連タンパク質ataxin-3の細胞内相挙動
  • 2024 - 2025 細胞内生体分子濃度定量法の確立と液液相分離への応用
  • 2024 - 2025 インジェクションーラマン/ブリルアン顕微鏡による細胞内タンパク質相挙動の定量解析
  • 2020 - 2024 細胞内の水を用いた細胞内微小環境の定量評価法の確立と応用
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Papers (59)：
  • Keisuke Koga, Shinji Kajimoto, Yuta Yoshizaki, Hiroaki Takahashi, Lisa Kageyama, Tomohiro Konno, Takakazu Nakabayashi. Establishment of a Method for the Introduction of Poorly Water-Soluble Drugs in Cells and Evaluation of Intracellular Concentration Distribution Using Resonance Raman Imaging. The Journal of Physical Chemistry B. 2024. 128. 6. 1350-1359
  • Hiroyuki Yamakoshi, Daiki Shibata, Kazuki Bando, Shinji Kajimoto, Aki Kohyama, Syusuke Egoshi, Kosuke Dodo, Yoshiharu Iwabuchi, Mikiko Sodeoka, Katsumasa Fujita, et al. Ratiometric analysis of reversible thia-Michael reactions using nitrile-tagged molecules by Raman microscopy. Chemical Communications. 2023
  • Kohei Yokosawa, Mitsuki Tsuruta, Shinji Kajimoto, Naoki Sugimoto, Daisuke Miyoshi, Takakazu Nakabayashi. Quantification of the concentration in a droplet formed by liquid-liquid phase separation of G-quadruplex-forming RNA. Chemical Physics Letters. 2023. 826. 140634-140634
  • Shogo Moriyama, Miyu Mae, Daiki Shibata, Hiroyuki Yamakoshi, Shinji Kajimoto, Takakazu Nakabayashi, Takayoshi Ishimoto, Kaiki Mogi, Hironao Sajiki, Shuji Akai, et al. Multiple deuteration of triphenylphosphine and live-cell Raman imaging of deuterium-incorporated Mito-Q. Chemical Communications. 2023. 59. 81. 12100-12103
  • Ren Shibuya, Shinji Kajimoto, Hideyuki Yaginuma, Tetsuro Ariyoshi, Yasushi Okada, Takakazu Nakabayashi. In situ Quantification of Biomolecular Concentration of Cytoplasmic Membraneless Organelles in a Living Cell. 2023
ｍore...
MISC (16)：
  • Takakazu Nakabayashi, Shinji Kajimoto. ラマンイメージングを用いた細胞内の水・夾雑環境の理解. 2022. 100. 7. 367-370
  • Takakazu Nakabayashi, Shinji Kajimoto. ラマン分光による細胞の中の水の計測と分子夾雑環境・温度イメージングへの応用. 2022. 51. 238-242
  • Takakazu Nakabayashi, Kunisato Kuroi, Shinji Kajimoto. ラマン顕微鏡によるラベルフリーなタンパク質液滴定量法. Journal of Japanese Biochemical Society. 2022. 94. 3. 444-448
  • Takakazu Nakabayashi, Shinji Kajimoto. ラマン散乱で細胞の中の水を見る. 2022. 75. 3. 209-209
  • 村上一輝, 梶本真司, 中林孝和. ラマン顕微鏡を用いた疾患関連タンパク質の液-液相分離の定量評価. 細胞. 2021. 53. 8. 548-551
ｍore...
Books (5)：
  • フロントランナー直伝 : 相分離解析プロトコール : 今すぐ実験したくなる、論文にはないコツや技
    羊土社 2022 ISBN:9784758122597
  • ラマン分光スペクトルデータ解析事例集
    技術情報協会 2022 ISBN:9784861048722
  • Multi-Parametric Live Cell Microscopy of 3D Tissue Models
    Springer 2017
  • 東北大学自然科学総合実験2013
    東北大学出版会 2013 ISBN:9784861632204
  • Advances in Bio-Imaging: From Physics to Signal Understanding Issues, State-of-the-Art and Challenges
    Springer 2012 ISBN:9783642255465
Lectures and oral presentations  (82)：
  • In situ quantification of biomolecular concentration in stress granules formed via LLPS in a living cell
    (International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan 2023)
  • Quantification of LLPS of neurodegenerative disease-related proteins by Raman/Brillouin imaging
    (第11回 創生応用医学研究センター オンラインセミナー 2022)
  • Raman and Brillouin microscopy as a tool for quantitative study of LLPS
    (Symposium on Phase Separation by Biopolymers: Basics and Applications in 第60回日本生物物理学会年会 2022)
  • ラマンイメージングを用いた神経変性疾患関連タンパク質の液液相分離の定量解析
    (2022)
  • Label-free visualization of intracellular temperature by Raman imaging of water in a cell
    (Chemistry Symposium on 25th Anniversary of Dalian University of Technology and Tohoku University 2022)
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Education (2)：
  • 2002 - 2007 Tohoku University Graduate School of Science Department of Chemistry
  • 1998 - 2002 Tohoku University Faculty of Science Department of Chemistry
Professional career (1)：
  • 理学博士(化学) (Tohoku University)
Work history (5)：
  • 2021/03 - 現在 Tohoku University Graduate School of Pharmaceutical Sciences Associate Professor
  • 2016/09 - 2021/02 Tohoku University Graduate School of Pharmaceutical Sciences Senior assistant professor
  • 2007/08 - 2016/08 Tohoku University Graduate School of Science Assistant professor
  • 2011/03 - 2013/03 Tohoku University Center for the Advancement of Higher Education Assistant professor
  • 2007/04 - 2007/07 Institute for Molecular Science
Committee career (1)：
  • 2011 - 2015 日本化学会 新領域研究グループ 液相高密度エネルギーナノ反応場 メンバー
Awards (3)：
  • 2022/07 - Graduate School of Pharmaceutical Science, Tohoku University 研究科長賞
  • 2021/07 - Graduate School of Pharmaceutical Science, Tohoku University 研究科長賞
  • 2019/07 - Japanese Society for Photomedicine and Photobiology 奨励賞
Association Membership(s) (7)：
Japanese Society for Photomedicine and Photobiology ,  International Association of Colloid and Interface Scientists ,  Japan Society for Molecular Science ,  The Japanese Photochemistry Association ,  The Chemical Society of Japan ,  The Pharmaceutical Society of Japan ,  THE BIOPHYSICAL SOCIETY OF JAPAN
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